“an increasing trend”

We found an increasing trend in carbapenem resistance over the past ten years ( p = 0·009) (Fig. 4 , table S4).

In the 3-group comparison, neutrophils percentage ( p = 0.017), NLR ( p = 0.015) and MLR ( p = 0.021) showed an increasing trend from healthy controls to remitters then non-remitters, while lymphocytes percentage ( p = 0.009), platelet count ( p = 0.034) and red blood cell counts ( p <0.001) showed a decreasing trend.

Overall, we observed an increasing trend in the number of distinct STs over time ( p = 9.18 × 10 −3 , r Pearson = 0.69; Fig. 1c ).

Among males, an increasing trend was observed from 2013 to 2018 ( APC = 10.29%, P < 0.01), followed by a significant decrease starting in 2018 ( APC =−30.78%, P < 0.01).

However, following treatment with LTP and AP, the concentrations of ZO-1 and occludin in renal tissues showed an increasing trend ( P < 0.01) (Figure 3A and B ).

Strength-based subgroup analyses revealed that consumption of 75-mcg and 125-mcg preparations showed an increasing trend in subsequent periods compared to BfR ( p < 0.01 for all comparisons, Fig. 3 a).

3.3 Labor outcomes There was an increasing trend in the intrapartum cesarean section rates from 7.4% (2012) to 8.4% (2021); p < 0.01.

However, the HDRS scores at T2 showed an increasing trend compared to the T1 scores (Wilcoxon test, Z = −3.504, P < .01). 3.3.

Conversely, cyberbullying perpetration exhibited an increasing trend over time (Estimate = 0.05, SE = 0.01, P < .01).

Among the Access, Watch, and Reserve classification groups, the Watch group showed the highest usage; further, the Access group showed a decreasing trend, whereas the Watch and Reserve groups showed an increasing trend (p < 0.01).

Results The total incidence of HDP was 45.17 ‰ (95 % CI: 44.14‰–46.20 ‰), and the subtypes of HDP showed an increasing trend from 2012 to 2021 (all P < 0.01).

However, for Cat II-IV cesareans, there was an increasing trend in delays, as shown in Table 1 (Mantel-Haenszel p<0.01).

Results 76,873 patients were diagnosed with GBC with decreasing incidence rates in all races/ethnicities except NHB who experienced an increasing trend between 2001 and 2014 (APC = 2.08, p < 0.01) and plateauing afterward (APC = −1.21, p = 0.31); (AAPC = 1.03, p = 0.03).

In addition, the protein levels of COX-2 and iNOS in the liver tissue exhibited an increasing trend with the occurrence of acute ALD ( P < 0.01), but they were significantly reduced after administration of medium- and high-dose RDAE ( P < 0.05, P < 0.01) ( Fig. 7 A–G).

In the unadjusted analyses, there was an increasing trend in the annual rate of NF cases over time (1.9 cases/year, 95% CI: 0.7 to 3.1; p < 0.01; R 2 = 0.60; Fig. 3 A).

From 2005 to 2020, the height, weight, and BMI of both males and females showed an increasing trend with time ( P <0.01).

The first cases appeared in 2018 (0.01/1000 patient-days), increasing to 0.10–0.16/1000 patient-days in subsequent years—an increasing trend in 2018–2024 (average +0.02/1000 patient-days per year; p = 0.01).

ES features and in-hospital management The rate of VF demonstrated an increasing trend across STORM stages ( P -trend < 0.01), rising from 27.3% in STORM-1 to 57.1% in STORM-5 ( P < 0.01).

Throughout the aging process, the SP content of oat seeds exhibited an increasing trend, with highly significant differences observed in the SP content of the two varieties ( P < 0.01).

The TX90p (percentage of warm days) presents an increasing trend in the historical period (z = 2.87, p < 0.01) but shows fluctuations in the future.

As shown in Figure 5c and d, compared to the control group, the LPS group exhibited an increasing trend in the expression of SOD, CAT, Nrf2, and HO-1 (P < 0.01).

THA was the preferred treatment for patients in the 55–64 years and 65–74 years age classes, with an increasing trend ( p < 0.01) over the 23 observed years in both classes.

Authorship analysis showed an increasing trend in co-authorship ( P < 0.01), with the average number of authors per paper reaching 10.4 by 2024.

Concurrently, an increasing trend in the frequency of Foxp3 + Tregs was observed ( p < 0.01); however, given the limited sample size ( n = 5), this finding should be interpreted with caution and requires further validation in larger cohorts.

In addition, the mRNA expression level of triacylglyceride lipase ( ATGL ) and lipoprotein lipase ( LPL ) genes was an increasing trend in overexpression of GPX2 ( P < 0.01) ( Fig 2D ).