“an increasing trend”

During the analyzed period, an increasing trend in the use of contraception before hospital discharge was observed (Cochran-Armitage test: z = 6.07; p < 0.01), as well as a trend of increased insertion of IUD (Cochran-Armitage test: z = 8.07; p < 0.01).

From 2005 to 2020, the height, weight, and BMI of both males and females showed an increasing trend with time ( P <0.01).

In the unadjusted analyses, there was an increasing trend in the annual rate of NF cases over time (1.9 cases/year, 95% CI: 0.7 to 3.1; p < 0.01; R 2 = 0.60; Fig. 3 A).

The CD4/CD8 ratio of schizophrenia patients in the 9 studies showed an increasing trend compared with the control group (SMD=0.38, 95%CI: 0.19–0.56, P <0.01, I 2 =34%).

Throughout the aging process, the SP content of oat seeds exhibited an increasing trend, with highly significant differences observed in the SP content of the two varieties ( P < 0.01).

The percentage of elastic fibers, micro-arterial wall thickness, and micro-arterial area showed an increasing trend ( p < 0.01) from 0.5-year-old yaks to 2.5-year-old yaks and then to 4.5-year-old yaks.

During the summer nighttime, the warming effect shows an increasing trend of 0.040 K/decade ( p = 0.01), but the magnitude is only about one-fifth of the daytime ΔLST s negative trend (−0.188 K/decade, p = 0.01) (Fig. 1c ).

Only one allergen, p ‐phenylenediamine, gave an increasing trend with age ( p < 0.01).

With the increase of fertilization level F 0 to F 2 , the GP and GR of WL354HQ and Xinmu No.4 alfalfa showed an increasing trend, and the GP was highest in F 2 W 2 treatment (0.83% and 0.83%), which were 33.87% and 31.75% higher than that of F 0 W 1 , respectively ( P < 0.01).

There were 1761 (5.1%) pre-emptive kidney transplantations over the entire period, with an increasing trend in both absolute (4.7% in 1991–1995 to 7.5% in 2016–2021, P < .01) and relative (5.2 pmp in 1991–1996 to 8.7 pmp in 2016–2021) terms (Table 3 ).

After 24 h of treatment with different concentrations of CUR, the apoptosis rate showed an increasing trend with higher drug concentrations, reaching a statistically significant difference at 25 μmol/L ( p < 0.01).

THA was the preferred treatment for patients in the 55–64 years and 65–74 years age classes, with an increasing trend ( p < 0.01) over the 23 observed years in both classes.

In addition, the mRNA expression level of triacylglyceride lipase ( ATGL ) and lipoprotein lipase ( LPL ) genes was an increasing trend in overexpression of GPX2 ( P < 0.01) ( Fig 2D ).

Additionally, ALB levels exhibited an increasing trend in the ARNI group and were notably higher than at baseline after treatment in the ARNI group [37.5 ± 4.7 g/L vs. 39.3 ± 5.4 g/L, P < 0.01].

The proportion of total outpatient visits of member public hospital has shown an increasing trend by 0.063% before the reform ( p < 0.01), and decreased by 0.089% per month ( p < 0.05) after the reform, while the change of member private hospital showed no significant change.

The first cases appeared in 2018 (0.01/1000 patient-days), increasing to 0.10–0.16/1000 patient-days in subsequent years—an increasing trend in 2018–2024 (average +0.02/1000 patient-days per year; p = 0.01).

The Cochrane-Armitage test indicates a declining trend in HGVBP (P = 0.01) and an increasing trend in SR (P < 0.01).

As shown in Table 1 , there was an increasing trend in BMI, SBP and DBP with the severity of disease, and the highest values were observed in the sPE group ( P < 0.01).

In contrast, brodifacoum residues showed only an increasing trend over time ( p -value = 0.01; R 2 = 0.196) ( Figure 3 b).

Although HPV52 showed an increasing trend (Z = 2.797, p < .01), no discernible upward or downward trend was observed for total high-risk HPV (Z = 0.637, p > .05).

Furthermore, in 2009, 2012 and 2018, the percentage of drugs prescribed from the essential medicine list was 66.50%, 78.50% and 80.34%, respectively, and the percentage of drugs prescribed using generic names was 61.29%, 70.90% and 70.65%, respectively, all of which initially showed an increasing trend and then stabilised (p<0.01) ( table 3 ).

In the GG, the scores for happiness, appetite, hygiene, general health and owner pain showed an increasing trend starting from D2 ( P < 0.01); the mobility score decreased at D1 ( P < 0.01), followed by an increase at D3 ( P < 0.01), and the vet pain score exhibited a decreasing trend at D1 ( P < 0.01), followed by an increase starting from D2 ( P < 0.01).

Allogrooming and self-grooming did not have an increasing trend over the study period, but d 94 had the highest frequency of both allogrooming ( p < 0.01) and self-grooming ( p < 0.05) compared to the other assessment days.

Notably, the incubation period and SI of the five had both a progressive shortening trend ( p < 0.001); Moreover, R 0 of the five were 2.39 (95% CI: 1.30–4.29), 3.73 (95% CI: 2.66–5.15), 5.28 (95% CI: 3.52–8.10), 5.54 (95% CI: 2.69–11.17), 7.39 (95% CI: 2.97–18.76), with an increasing trend gradually ( p < 0.01); HSAR of the five were 25.5% (95% CI: 20.1–31.7%), 27.4% (95% CI: 22.0–33.4%), 42.9% (95% CI: 34.3–51.8%), 53.1% (95% CI: 45.0–60.9%), 41.4% (95% CI, 25.5–59.3%), also with an increasing trend ( p < 0.001).

7.6 %, p < 0.01) showed fluctuating utilization rates for ARAs between 2008 and 2020, whereas female patients showed an increasing trend in utilization rates (6.6 % vs. 8.9 %, p < 0.01), similar to the trend observed in the main analysis ( Fig. 3 ).