“an increasing trend”

During the five-year period, some diseases displayed an increasing trend, while others showed a declining trend.

Self-reported discomfort, pain, or adverse sensations were observed in some participants, particularly during early sessions, but did not show an increasing trend over time.

Supernatants from microglia exposed to EVs loaded with let-7e or miR-548b-3p showed an increasing trend of TNF release, however, those TNF release levels did not reach statistical significance.

orientale will show an increasing trend under both scenarios (SSP126 and SSP585) during the two future periods (2050s and 2090s).

While hsa-miR-9-5p exhibited an increasing trend, this difference lacked statistical significance ( Supplementary Table 6 ).

An increasing trend in prevalence was observed across all age groups over the past two decades, with the highest prevalence consistently observed in individuals aged ≥80 years.

Consistent with WFP, the proportions within patients aged 60–69 and ≥80 years exhibited an increasing trend.

It can be seen that with the increase of moisture content and interval time, the displacements of the pile tops and ground surface around piles both show an increasing trend.

When the measurement point is within a 20 m range from the total station, the mean square error of the deviation of the measurement point shows an increasing trend, with the value changing from 0.11 mm to 0.12 mm.

Across all ZS replacement levels, the compressive strength showed an increasing trend, reaching a maximum improvement of approximately 8% compared to the control.

An increasing trend in proline content was observed with rising salinity levels in both cultivars and across all bacterial treatments.

Hence, their fractions also seem to be on an increasing trend.

In addition, tissue immunofluorescence results showed that the expression of Caspase-1 and Asc in mice livers of HFD plus alcohol binge group showed an increasing trend compared with the normal group, while TYTWT reduced their expression in a dose-dependent manner with the most effective dose at 200 mg/kg ( Fig. 3 E and F).

This study revealed an increasing trend in TAZ/PIPC and carbapenem resistance across regions in Japan over time, highlighting the need for close monitoring in the future.

Opportunities for In‐Depth Mechanistic Studies and Precise Product Quantification Using Advanced In Situ Tools There has been an increasing trend in the development and implementation of in‐situ and operando techniques to characterize the evolution of electrocatalysts, and there is further scope for adopting more sophisticated and even hybrid analytical methods.

Notably, epidemiological studies have revealed an increasing trend in CRC incidence and mortality among younger populations, statistical projections indicate that by 2030, ~33% of colorectal cancer cases will occur in individuals <50 years of age ( 3 – 5 ), which is mainly associated with changes in dietary habits, environmental factors and unhealthy lifestyle choices, such as smoking, alcohol consumption and lack of exercise ( 6 – 9 ).

Across pooled samples, the pro-inflammatory cytokines TNF-α, IL-1β, IL-6, IL-8, and IL-1α exhibited an increasing trend congruent with the progressive enhancement of innate immune activation ( Kusiak and Brady, 2022 ; Van Dyke, 2017 ).

Both TPC and TFC showed an increasing trend with rising ethanol concentration, reaching their peak at 60% ethanol.

The moisture content of the coal sample showed an increasing trend.

5 A, our proposed CTRS effectively divided LUAD cases into two subgroups across all cohorts, with CTRS scores showing an increasing trend from low-to high-risk individuals.

Globally, the local drift in the DALYs rate attributable to high BMI in PCAD exhibited an increasing trend, with the rate of this increase gradually diminishing as age progressed (Fig. 4 A).

In Southeast Asia, Singapore reported an incidence of GERD at 10.5%, with an increasing trend over the years.

Background There is an increasing trend in the utilisation of mobile applications (apps) and smartphones in rehabilitation.

In our study, 36.2% of OPSCC were positive for p16 INK4a whilst 27.7% of OPSCC were positive for both p16 INK4a and HPVDNA, in contrast with a previously published study on Malaysian OPSCC cases identified over a 12-year period from 2004 to 2015 that showed that 25% of cases were p16 INK4a positive and 16.7% ( n = 10) of cases were positive for both p16 INK4a and HPV DNA (using in situ hybridization), highlighting an increasing trend of OPSCC cases attributable to HPV [ 5 ].

Furthermore, unlike the overall bacterial community diversity which peaked at the mid-wintering stage and then declined, the α-diversity of putative pathogens exhibited an increasing trend from mid-stage onward, potentially reflecting cumulative exposure effects resulting from complex anthropogenic contacts.