The analysis showed an increasing trend in the risk of all-cause mortality across CAD-RADS categories (Regression co-efficient = 0.046; 95% CI: 0.008-0.084; p = 0.018).
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There was an increasing trend in ISSSF in BBFP children (APC 0.46%, p = 0.018).
The trend of increases in plasma S1P with complications is further detailed in Table 5 , where they were all significantly higher than in patients without complications, with an increasing trend from ophthalmopathy ( p = 0.018), neuropathy ( p = 0.007), nephropathy ( p = 0.004), and mixed complications ( p < 0.001).
Evidence showed an increasing trend across WC tournaments, indicated by a significant linear relationship between RAE effect size and year of tournament from 1997 to 2015 (Spearman’s φ = .72, p = .018, strong association ).
No significant change in circulating B cell levels or their subsets was detected at any time point post-infection, except for an increasing trend in CD21 − B cells at 2 dpi ( p = 0.0183) ( Figure 7 ).
The seasonal Mann-Kendall test revealed an increasing trend (although with a small slope value) in Changjiang River discharge ( n = 732, R 2 = 0.002, p = 0.0190) during the past several decades (see the blue line in Fig. 2 a), probably corresponding to combined effects of climate change, land-use management change, and ongoing vegetation greening over the river basin (Piao et al. 2015 ; Chen et al. 2019a ).
After the intervention, there was a decreasing trend in the IAC of meropenem (coefficient = −0.03, p = 0.008) but an increasing trend for imipenem (coefficient = −0.02, p = 0.019).
On analysis, there was an increasing trend toward recurrence in patients with hypertension (OR: 3.72; 95% CI: 2.78-5.13; p = 0.019).
The relative abundances of Bacteroidota, Proteobacteria, and Spirochaetes were lower in the RT group than in the CON group, with a decrease observed in Bacteroidota in the RT group on days 7 and 28 after rumen fluid transplantation ( p = 0.013), while Proteobacteria showed a decreasing trend in the CON group and an increasing trend in RT; however, this was only at day 4 ( p = 0.019).
An increasing trend in Ct values for ORF1b/N (SARS CoV-2), M1/NS2 (Flu A/B), M (RSV A/B) was found from T1 to T3, reaching statistical significance for the SARS-CoV-2 RdRp ( p = 0.0199) (Fig. 2 ).
Serum Ang-1 levels did not change significantly in cholecalciferol group (mean change: 1.36 ng/ml; 95% CI: -2.39 to 5.11 ; p = 0.280; Table 3 ) while in placebo group showed an increasing trend (mean change: 5.63 ng/ml; 95%CI: 0.51 to 10.75; p = 0.020).
Variation in the abundances of these taxa was best explained by HFF behaviors, with an increasing trend in microbial abundances indicated in HFF-low risk (coordinate = 1.43, p = 0.02; Fig. 1B ).
The maximum daily fraction of western US grid cells with simultaneous PM 2.5 /ozone co-occurrence during July to September has more than doubled (from 18.9 to 44.6%) over the past two decades, with an increasing trend of ~1.35% per year ( P = 0.02) ( Fig. 1D ).
Ranging from complete tumor regression (pathological tumor regression grade 0; pTRG0) to poor regression (pTRG3), the ctDNA clearance rate during nCRT showed a significant decreasing trend (95.7%, 77.8%, 71.1%, and 66.7% in pTRG 0, 1, 2, and 3 groups, respectively, P = 0.008), while the detection rate of acquired mutations in ctDNA showed an increasing trend (3.8%, 8.3%, 19.2%, and 23.1% in pTRG 0, 1, 2, and 3 groups, respectively, P = 0.02).
After the implementation of ISM policy, the total weight decreased immediately and an increasing trend change was found ( β 2 = − 3719.05, p = 0.02; β 3 =250.13, p = 0.003).
From year 2013 onwards, the rate of the 0 to 17-year-old population referred to child protection services showed a significant decrease in RD (AAPC = −6.9; 95% CI: −10.8,−2.8; p = 0.013) compared to an increasing trend in the whole country (AAPC = 1.9; 95% CI: 0.6, 3.3; p = 0.020) (AAPC difference = 8.9; 95% CI: 6.2, 11.5; p < 0.001).
An increasing trend in annual positivity was significant only for big brown bats ( P = 0.02), and was circumstantially linked to a geographic cluster.
We found a significant association between NC and an increasing trend of homeostasis model assessment of insulin resistance (HOMA-IR), adjusting for age and other cardiometabolic risk factors, in both men ( P = 0.02) and women ( P = 0.004).
In contrast, whereas 11 (8—16) million in 1990 were affected with an ASYLDsR of [242 (162—344) per 100,000 people] (Table 2 ). The ASIR of neck pain between 1990 and 2021 showed an increasing trend globally, AAPC = 0.04 (95% CI, 0.01 to 0.07, P = 0.02).
For MMT clinics receiving PMES only, there was an increasing trend before the intervention in the average 3-month retention rate in the overall MMT clinics (baseline slope = 0.07%, p = 0.02), with similar point estimates failing to reach statistical significance in individual scales of MMT clinics.
There was an increasing trend of the virological response with time since the cessation of thymosin treatment (p = 0.02) [ 23 ].
The event rate showed an increasing trend, with 3.7%, 7.0%, and 13.0% in Group 1, Group 2, and Group 3, respectively (log‐rank P =0.02) (Figure 5 ).
Payments to teaching hospitals ranged from 0.01% (in “Research”) to 0.19% (in “Education and training” and “Space rental and facility fee”) of net US revenue and payments in “Education and Training” showed an increasing trend ( p = 0.02), while payments in “Direct payments” showed a decreasing trend over time ( p = 0.02).
As O-DMA concentrations increased, the FT3/FT4 ratio demonstrated a decreasing trend (Standardized β = − 0.003, P = 0.04), while TFQI exhibited an increasing trend (Standardized β = 0.019, P = 0.02).
From November 2023, SCFA-producing genera showed an increasing trend ( p = 0.02; Fig. 1 B).