Notably, a large-scale historical cohort study of Israeli diabetic patients ( n = 145,617) revealed through analysis with advanced statistical models that the association between metformin exposure levels and prostate cancer risk is not fixed but may exhibit dynamic characteristics: short-term exposure (in the first year) even showed an increasing trend in risk, whereas long-term exposure (2–7 years) exhibited a potential protective effect, with an overall inconsistent association [ 26 ].
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“an increasing trend”
Sighted at
p<0.09
In the literature
2022 ), even though this study did demonstrate an increasing trend in WSS for PAH.
A Taiwan National Database analysis showed an increasing trend, from 21.8 per 100,000 in 2002 to 40.2 per 100,000 in 2013, suggesting greater recognition and diagnosis over time ( Chung et al., 2013 ).
The prevalence of GERD in China is approximately 1.9%−7.0% ( 1 ), showing an increasing trend year by year.
Fe content did not decrease after digestion under any of the applied cooking methods; on the contrary, it generally exhibited an increasing trend, indicating effective release of iron into the soluble fraction during digestion, thereby confirming liver as a valuable dietary source of this mineral.
Two large population-based studies demonstrated the high frequency of polypharmacy in the ASD population, sitting at around 30%, and confirmed that SSRIs account for a relevant percentage of prescriptions (5.6% for fluoxetine and 5.5% for sertraline) with an increasing trend over the years 25 , 26 Why It Is Important To Do This Review To date, a Cochrane Systematic review published in 2013 27 has examined the efficacy of 4 SSRIs (fluoxetine, fluvoxamine, fenfluramine and citalopram) in both adult and children populations.
The average age of patients showed no significant change, while the proportion of advanced maternal age cases exhibited an increasing trend, which may be associated with postponed childbearing intentions.
The discrepancy may indicate an increasing trend in mental health service utilization in recent years, but it may also reflect a true rise in the prevalence of mental disorders.
However, for positive sounds, higher suggestibility was associated with both an increasing trend for dispersion (pd = 0.92) and a steeper distance-dispersion slope (pd = 0.95), suggesting that suggestible individuals showed greater and more distance-dependent variability for positively-valenced stimuli.
We can expect an increasing trend not only in Slovakia but also worldwide. 4.
Similarly, percutaneous techniques accounted for 1.6% of all cases in the 2011 survey and showed an increasing trend as reported by Ishii et al. 13 ) .
Of note, quartile analysis demonstrated that UF risk generally exhibited an increasing trend with higher TyG and UHR levels.
Conclusion This study showed an increasing trend in stunting and obesity among school-aged children over three years.
[ 17 ] reported that supplementing 0.45 g/kg and 0.6 g/kg GML to the diet of yellow-feathered broilers exerted no significant effects on the serum contents of TG, LDL-C, and HDL-C, with only an increasing trend in TG content observed.
For instance, a slight decrease in prevalence was observed in Sicily between 2020 (25.4%) and 2021 (21.6%) [ 35 ], whereas an increasing trend was reported in Portugal, where prevalence doubled over a 10-year period [ 27 ].
Both curves show an increasing trend which means that the model is getting better with time.
Both WUE (WUE) and agronomic nitrogen use efficiency (AEN) showed an increasing trend followed by a decline as N input increased, while nitrogen use efficiency (NUE) declined with higher N rates, indicating diminishing returns and potential N losses at excessive application levels.
The results showed that 2-dehydropantoate 2-reductase (EC:1.1.1.169), which participates in pantothenate/coenzyme A biosynthesis, was slightly higher in the PH group than in the NC group, and that alkanesulfonate monooxygenase (EC:1.14.14.5), which is related to organosulfonate degradation and sulfur metabolism, also exhibited an increasing trend in the PH group.
TCM syndrome scores exhibited an increasing trend over time in both groups, suggesting a progressive worsening of the spleen-kidney deficiency syndrome throughout chemotherapy.
It was observed that the uptake showed an increasing trend at the highest air velocity and exhibited slight variations depending on the tray position.
An increasing trend of ADR reports from consumers was already observed from 2008 onwards, especially after 2012.
The bolt connection stress show an increasing trend during the unloading phase, reflecting an enhancement in the bolt clamping effect.
The MSP results also showed that after 24 h of treatment with 100 or 125 μM ω‐3PUFAs, the methylation level of the STK31 promoter region in NOZ and GBC‐SD cells exhibited an increasing trend (Figure 3B,C ).
According to official statistics from the Food and Agriculture Organization of the United Nations (FAO), global cucumber production reached approximately 98 million tons in 2023, indicating an increasing trend and underscoring the significance of this crop 4 .
Although no significant differences were observed across N stages, the LINC01117 expression levels showed an increasing trend with advancing N stage ( Fig. 2I ).