aeruginosa showed an increasing trend over time ( Rs=0.738, P=0.037 ).
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Among all microvascular complications, there was an increasing trend in the proportions developing impaired eGFR (3.6 vs. 3.9 vs. 6.6%, trend P = 0.037) and ESRD (0 vs. 1.5 vs. 2.3%, trend P = 0.036) among those with 0, 1, or 2 copies of the HP 2 allele, respectively.
Secondary analyses An increasing trend of postpartum suicide attempt was indicated among adolescent fathers (aged 11–19 years) (IRR 1.06 (1.00–1.11), P = 0.037), but the association is no longer significant after adjusting for multiple comparison (adjusted P = 0.096).
The unit cost of high-risk population intervention showed a declining trend over the years (r=−0.791, p=0.034) (see online supplementary appendix C), while the unit cost of public awareness showed an increasing trend over the years (r=0.785, p=0.037) (see online supplementary appendix D).
An increasing trend of the AA/DHA ratio was observed across quartiles of the “Proteins and fatty acids with legs” dietary pattern ( p = 0.0378).
Despite representing only a small proportion of the total diagnoses, an increasing trend was observed each year ( P = 0.038).
The susceptibility of ampicillin showed an increasing trend (p=0.038), nevertheless it was only less than 40%.
Cytoplasmic PANK4 levels showed an increasing trend in aged WT mice [One-way ANOVA: F (2, 13) = 4.242, p = 0.0382; Figures 2D,G ], with significant reduction in Pank4-CKO versus 18M+WT ( p = 0.0488).
Similarly, the prevalence of UI exhibited an increasing trend in relation to percent total body fat and percent trunk fat ( P = .039 and P = .008, respectively).
Specifically, we observed an increasing trend in risk of migraine as COVID-19 genetically increased (β = 0.298, 95% confidence interval [CI]: 1.015-1.790, p = 0.039), and the data were robust without obvious bias.
During the study period, there was an increasing trend toward using MCS (Cohran Armitage P = 0.039).
The TTI rate among them was 4.76%, with an increasing trend ( b = 0.082; p = 0.039), even though we did not observe any changes in the number of donations.
Pre-pregnancy body mass index of reproductive-age women shifted from an increasing trend in the pre-epidemic period to a declining trend in the post-pandemic period (β=-0.05, 95%CI: -0.10 to -0.01, P = 0.039), in line with the accelerated decline of birth weight nine months later.
Using the RoB-2 tool, only 22 (23.9%) published trials had a low risk of bias (Figure S3), with an increasing trend over time (OR: 1.09; P = 0.039).
Three studies assessed changes in femoral neck BMD, and the random-effects model showed an increasing trend (SMD = 0.24, 95% CI: −0.01–0.49), but this did not reach statistical significance, with moderate heterogeneity (I 2 = 70%, p = 0.04).
The number of scholarly activities per resident also showed an increasing trend over time ( P = .04).
Our time-series analysis documented an increasing trend in the monthly rates of HIV tests per 1000 patient-visits before the policy change (average monthly increase of 0.19 [CI, 0.01–0.38], p = 0.04) ( Figure 1A ).
The average annual age-adjusted incidence of TAA repair was 3.5 per 100,000 person-years (95% confidence interval [CI]: 3.2-3.9), with an increasing trend over time ( P = 0.04; Table 1 ).
Among individuals under 19 years of age, an increasing trend in SLE prevalence was observed between 2010 and 2015 (APC=22.9%; p=0.0400), sustained from 2015 onwards.
An increasing trend in mortality HRs was observed with decreasing CD4% in the crude analysis, and adjusted for age, sex, and PVL ( p = 0.04).
However, for Hispanic or Latino patients, there was an immediate decrease in volume levels after the shutdown to approximately three quarters of its preshutdown level and an increasing trend over time after shutdown ( p =0.04 and 0.006, respectively) ( Figures 2 and 3 and Table 2 ).
Fluconazole-non-susceptible Candida isolates showed an increasing trend from 2021 ( p = 0.040), attributed to increases in C. glabrata and C. krusei BSIs ( Figure 1 and Supplementary Figure S1 ).
Kaplan-Meier analysis demonstrated an increasing trend in cumulative percentage of monthly admissions within 30-days of treatment ( P = .04); 6% (4 of 70) in December 2020, 8% (17 of 216) in January 2021, 11% (31 of 281) in February 2021, and 13% (11 of 82) in March 2021 ( Figure 1 ).
There was an increasing trend in the percentage of infants receiving multiple PND courses from 25% in 2010 to 34% in 2020 (p=0.04).
However, the frequency of NPBs shows an increasing trend with increasing GS ( p = 0.04; p trend = 0.01; Figure 2 B).