In addition, we noted significantly higher levels of CD107a in PBMC CD8 + -T EMRA and approaching significance in IFN-γ in PBMC CD8 + -T EM as compared with their LPMC counterparts in unvaccinated volunteers ( Table 1 ; blue highlights).
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R-MG group had significantly shorter drug reducing duration than NR-MG, and there were numerical trends of less duration from steroid initiation to stable status, lower accumulated steroid doses before stable status and higher steroid-reducing speed in R-MG group, which were approaching significance, whereas no statistical difference was found in clinical characteristics.
Changes in coherence across therapy were linked with children’s post-intervention behavioural symptoms and were approaching significance for internalizing problems, but were not associated with externalizing problems.
For all analyses, we defined significance using an alpha level of 0.05 and define differences that yield p -values in the range of 0.05 ≤ p < 0.07 as statistical trends approaching significance.
Delayed EP treatment also suppressed nitrite levels induced by LPS, and decreased Inos transcript levels with a p -value approaching significance ( Supplemental Figure 3 ).
Relational Outcomes Even though few studies assessed dyadic or relational outcomes, programs that assessed relational health showed improvement in parent–child interaction following program participation, with effects approaching significance.
Vegetable intake (10 oz) was shown to be a significant parameter in the GR LOO model, whereas the interaction of MTHFR 677 with overweight BMI) was approaching significance with a p value of 0.059.
As for the smoking-related variables, the negative associations (approaching significance) between urinary cotinine (and craving) scores and WB SUV are consistent with prior research [ 37 , 38 ] whereby variables indicating greater cigarette smoke exposure were associated with lower levels of the neuroinflammation marker.
Pairwise contrasts, adjusted for multiple comparisons using the sequential Bonferroni correction, did not identify any significant difference between any conditions; however, non-significant trends for increased EMG were observed in the VR environment, with both VRL (3.8%; t (76) = 2.49; p = 0.075; CI: 0.000 – 0.004) and VRH (3.9%; t (76) = 2.557; p = 0.075; CI: 0.000 – 0.004) approaching significance compared to baseline (REO) ( Figure 3 ).
If these were removed, the correlation was no longer approaching significance (see Fig. 2 for scatterplots).
After 3 months, group therapy outperformed standard individual therapy ( d =1.270, p<0.001), with the difference approaching significance 1 year after therapy onset. 43 The trial involved children aged 3 years to 6 year and 11 months, corresponding to the age range of the present study.
Other factors approaching significance in the model include number of video/study guide views, the number of lectures attended, SAT scores, and year in school.
Other correlations with differences approaching significance existed between extent of resection and CD8+ TILs, sex and Foxp3+/CD8+ ratio.
S9 ), and after adjusting the P value using the Benjamini‐Hochberg correction, no differences between ethanol‐fed and control mice were observed (false discovery rate [FDR] corrected P < 0.05); however, calorie intake in weeks 3‐5 was slightly higher in control‐fed mice and approaching significance.
Specifically, they found 28 neonates to be positive for BE (in the range of 716–5440 ng/g), and compared with 33 control infants, they described ‘a negative correlation approaching significance (...) between BE and head circumference’.
However, we observed a difference approaching significance for WASO, in which there was a lower percentage of the mean absolute difference for a 14-day set than for a 7-day set ( Table 2 ).
Two miRNAs, miR-27b-3p and miR-17-5p, were downregulated 2.207- and 1.448-fold, respectively, approaching significance.
Adolescents with ADHD reported higher levels of substance use approaching significance in spring 2020 ( d = 0.22) and significant during summer 2020 ( d = 0.35) relative to adolescents without ADHD, despite similar mean levels on retrospective report of substance use three months prior to COVID (ADHD: M = 3.19, SD = 0.76; without ADHD: M = 3.33, SD = 1.19; t (260) = 1.04, p = 0.303, d = 0.13).
Although the changes did not reach significance in the khat or atorvastatin groups, the khat + atorvastatin group exhibited a higher value approaching significance, as seen in Figure 4 .
Figure 3 shows the correlations of PTBE volume with factors that were significant or approaching significance on univariable linear regression.
Effects of time and its interaction with treatment were displayed only when statistically significant or approaching significance.
[ 85 ], who found an association between sedentary behavior and higher BMI percentiles in children aged 9–15, our results indicate that ST was never a significant determinant, approaching significance only for the increment in FFM (negative association).
However, the observed p -value (0.08) approaching significance indicates the possibility of an association that might not have been detected due to the low event rates of stillbirth across the included studies.
The only interaction effects approaching significance were observed between the intervention and the comparison groups in social awareness among the younger age group in Latvia, and in self-management in Lithuania.
Scores of >2 indicated significant changes whereas scores of 1 to 2 showed changes approaching significance.