Barely Significant
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borderline significance

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borderline significancep = 0.051.0× alpha
For the secondary outcomes, there were significant reductions in fasting plasma glucose (−0.22 mmol/L; 95% CI: −0.39 to −0.04; p = 0.01; I 2 = 94%) and fasting insulin levels (−3.36 μIU/mL; 95% CI: −6.31 to −0.41; p = 0.03; I 2 = 97%), while a borderline significance in HOMA‐IR scores (−0.56; 95% CI: −1.12 to −0.01; p = 0.05; I 2 = 96%) but no significant differences in 2‐h OGTT or HbA 1 c measures.
borderline significanceP = 0.051.0× alpha
On Cox regression, LVH showed borderline significance for independent association with all-cause mortality (hazard ratio 1.57, 95% CI 1.01–2.44, P = 0.05) after adjustment for age (predictive of death with hazard ratio 1.09, 95% CI 1.07–1.11, P < 0.005) and sex (predictive of death with hazard ratio 1.68, 95% CI 1.19–2.38, P < 0.005) (Fig. 1 ).