“did not reach statistical significance”

In addition, FGFR4 overexpression showed a trend toward better overall survival, but it did not reach statistical significance (HR 0.610, 95% CI 0.370–1.008, P = 0.054) (Table 1 ).

In the subsequent years, a segment with a decreasing trend was identified during 2007–2017 with an APC of -10.6 (95% CI, -13.6 - -7.6; p = < 0.001) and another segment with an increasing trend during 2017–2021 with an APC of 7.2 (95% CI, -6.2–22.5), although the latter did not reach statistical significance as indicated by the confidence interval.

Although there was a decreasing trend in overall appropriateness over the monitoring time ( Figure 6 ), this trend did not reach statistical significance. 4.

Furthermore, patients with elevated chromogranin A (CgA) or high Ki67 showed a trend to poorer OS; however, these differences did not reach statistical significance (log-rank test p = 0.07).

A new left bundle branch block (LBBB), the most common conduction disturbance after TAVI, showed a trend toward a lower PPM stimulation rate in our data but did not reach statistical significance.

Three analyses demonstrated a trend toward significance, though they did not reach statistical significance ( p = 0.056–0.066).

On the other hand, after Ang II treatment, Apelin KO mice showed a trend of decreased expression of ACE2 in the heart, but this did not reach statistical significance ( Figure 2 B).

A numerical trend for higher 30-day mortality with TAVI compared with medical therapy did not reach statistical significance, neither in the individual studies nor in random-effects meta-analysis (8.0% versus 4.8%; RR 1.66; 95% CI 0.90 to 3.08; I 2 = 0%).

Paternal BMI in overweight/obese ASD children also showed an increasing trend, but did not reach statistical significance.

The Withdrawn ratings showed a trend in the same direction as the PDP ratings, but did not reach statistical significance.

History of prior abdominal surgery showed a trend toward more postoperative flap complications but this did not reach statistical significance ( P < 0.15).

No differences emerged between T1 and T2, although fathers showed a trend with increased stress scores—from session one to session six—that did not reach statistical significance.

Age showed a trend toward significance but did not reach statistical significance.

Radiotherapy showed a trend towards reduced risk but did not reach statistical significance (OR = 0.49, 95% CI: 0.21–1.13, p = 0.094).

Conversely, PDIA6 overexpression showed a trend towards decreased apoptosis in A549 cells, although this did not reach statistical significance (Fig.

A Danish randomized controlled trial in which vitamin D3 (1200 IU daily) was administered to patients with CD showed a trend towards lower rates of clinical relapse compared to placebo, although it did not reach statistical significance [ 114 ].

[W2]PTH(1-33)-CBD showed a trend towards decrease in tumor burden but did not reach statistical significance.

Having an elevated BMI showed a trend toward an association with developing postoperative infection but did not reach statistical significance (adjusted OR = 1.025, 95% CI = 0.999-1.052, P < .056).

Although there was a strong trend towards reduced 90-day mortality (PCC, 19% versus FFP, 35%), it did not reach statistical significance likely related to the small sample size [ 28 ].

in a comparison of FD to PRN regimens showed a trend toward better visual outcomes in FD group at the end of 1 year although the difference did not reach statistical significance.

Our study showed a trend towards higher IgA levels in the NTG group but this did not reach statistical significance.

The difference in PFS in this indirect comparison showed a trend favouring trabectedin, but did not reach statistical significance with a p value of 0.074.

Overall, survival analyses showed a trend toward better OS for HPV-positive (67% survival) compared to HPV-negative (27% survival) patients but that did not reach statistical significance ( p = 0.12), most probably due to the small number of HPV-positive cases ( Figure 4 A). 2.3. p16Ink4a Protein Immunohistochemical (IHC) Staining In view of the small number of HPV-positive HNSCC patients found in this cohort, and the limited amount of pathological materials available, a subset of 50 representative specimens were processed for p16 protein IHC staining.

Although these associations were nominally significant, they did not reach statistical significance after applying the Bonferroni multiple corrections, potentially due to the limited sample size.

Although there was a positive trend for improvement in leg pain for those with a shorter duration of symptoms, this did not reach statistical significance in our study.