Furthermore, this cluster (identified as “cDC1c”) showed a trend of positive Hif1a mRNA expression that did not reach statistical significance (Supporting Information: Figure S4B , Table S2 ).
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In the literature
As shown in Figures 6d and 6e , lysosomes from nfe2l2 -KO mice showed a trend toward reduced RNASE uptake in comparison with Nfe2l2 -WT littermates, although it did not reach statistical significance.
Mostly the studies were conducted on small-sized populations and results did not reach statistical significance, some suggesting a possible trend.
The research findings revealed that the intervention group showed a significant decrease in UACR after treatment (t = 5.1, p = 0.0), while the control group exhibited a decreasing trend but did not reach statistical significance (t = 1.65, p = 0.052) (Fig. 6 ).
Average IL-6 mRNA ( Figure 2 A) and secreted protein levels ( Figure 2 B) showed a trend for elevated expression in the HER2 neg lines compared to the HER2 pos lines, but differences did not reach statistical significance.
Further, miR‐579‐3p showed a trend for an interindividual difference from the first to the second biopsy in patients with HCC compared to the cirrhosis cohort, although it did not reach statistical significance (most likely due to a small sample size) (Fig. 2D ).
Meanwhile, figure 4B showed an increasing trend in the risk of mortality in young COPD compared with the gender, age, race, smoking and occupational exposure matched population, but it did not reach statistical significance (HR=1.395, p=0.269).
One immunoglobulin dose-comparative study (400 mg/kg daily given for 3 days versus, for 6 days) showed a trend for greater benefit in the prolonged treatment course in terms of median time taken to be able to walk with aid, but this result did not reach statistical significance [ 53 ].
Relative to the non-targeting control (NTC), stable knockdown of DVL-1 in MCF7 cells showed a trend of higher E 2 production, although this did not reach statistical significance.
Consistent with the correlation analysis, the risk of death from both ED and CVD did not reach statistical significance, but still indicated a positive trend.
Although differences did not reach statistical significance, a trend towards significance was strongest for the left and right SLF parietal sections.
A study within a university-based family medicine practice showed a trend toward better blood pressure control in the highest continuity tertile compared to the lowest; however, this trend did not reach statistical significance (-0.2 mmHg, p = 0.2) [ 20 ].
An interesting trend was observed with gram-positive infections having higher levels of the anti-inflammatory cytokine interleukin (IL)-10 as well as IL-17A and vascular endothelial growth factor (VEGF) compared to gram-negative infections, although these differences did not reach statistical significance.
17 One study in which first-degree relatives of PD patients and controls were interviewed and screened for tremor showed a trend toward increased risk of ET among family members of patients with PD, with 4.8% of relatives of PD patients having ET versus 3.5% of controls, though this did not reach statistical significance (p = 0.08). 60 The risk increased with younger onset of PD (5.8% of relatives had ET when PD onset was ≤66 years p = 0.006) and with tremor-dominant or mixed forms of PD.
A higher hemoglobin level showed a trend toward longer OS in univariate analysis, but did not reach statistical significance (HR 0.90, 95%-CI: [0.80; 1.01], p = 0.079).
In contrast to the broadly described increase in the literature[ 34 , 35 ], lactate levels in our cohort showed a decreasing trend in tumors that did not reach statistical significance due to the high variability between patients.
Paternal BMI in overweight/obese ASD children also showed an increasing trend, but did not reach statistical significance.
The Withdrawn ratings showed a trend in the same direction as the PDP ratings, but did not reach statistical significance.
History of prior abdominal surgery showed a trend toward more postoperative flap complications but this did not reach statistical significance ( P < 0.15).
The TXA treatment group showed a trend toward lower blood transfusion rates over the peri- and postoperative period, though it did not reach statistical significance.
SARM1 +/− mice showed a trend toward acceleration that did not reach statistical significance (median survival, 171 dpi; Fig. 2 C ).
Despite a clear trend, tumor grade did not reach statistical significance ( Figure 1 E).
Further analysis with either anti-CD20- or anti-HER2-coated beads showed a trend for more rosettes and thus better binding with IgA compared to IgG, but this did not reach statistical significance ( Figures 3F,G ).
Then, HR remained stable throughout the experimental period in MAS + CBD whereas in MAS + VEH it was a numerical trend to a decrease in HR which did not reach statistical significance.
A positive trend occurred in other parameters of the muscular endurance in TCC but did not reach statistical significance.