“did not reach statistical significance”

AFP also reduced serum endotoxin levels and showed a trend towards upregulating intestinal ABCG2 mRNA expression, though this did not reach statistical significance ( p > 0.05).

In the spleen, the rAAV6-SapM group showed a trend toward fewer CFUs compared with rAAV6-vector controls, although this difference did not reach statistical significance ( Figure 4 B).

The breed × sex interaction showed only a marginal trend after size correction but did not reach statistical significance (R 2 = 0.02779, F = 1.4914, p = 0.089).

An analysis based on the Korean National Health and Nutrition Examination Survey (KNHANES) showed a negative trend between green tea intake and COPD risk among smokers, but the association did not reach statistical significance and detailed stratification by tea type or consumption pattern was lacking ( 26 ).

SRS-22 scores showed a trend toward improvement but did not reach statistical significance.

Stratified analyses according to antiplatelet regimen In the SAPT subgroup, G4 showed a trend toward a higher 1-year risk of MACE compared with G1, although the association did not reach statistical significance (adjusted OR = 2.42, 95% CI 0.69–8.35, P = 0.154).

The M-HDAC3 −/− retinas showed a trend toward a decrease in Iba-1 count after crush; however, this did not reach statistical significance (Fig. 1C ).

The expression of Prdm16 showed an increasing trend but did not reach statistical significance.

Within the population with T2DM (N = 180), contrary to our initial hypothesis, metformin treatment showed a numerical trend towards shorter PFS, though this did not reach statistical significance (HR = 1.41, 95% CI [0.97–2.05], p = 0.069).

The urinary catheter removal time was significantly longer in the SLND group (β = + 1.24, 95% CI: 0.90–1.59, P < 0.001), while the time to first flatus showed a trend toward delay but did not reach statistical significance (β = + 0.35, 95% CI: − 0.01 to 0.70, P = 0.058).

No significant difference emerged in illness duration ( p = 0.383), while years of education showed a trend toward lower levels in the apathy group, though this did not reach statistical significance ( p = 0.057).

A higher LMR (≥ 3.0) showed a positive trend but did not reach statistical significance in adjusted models.

For 1‐year MACCE, GBM yielded an AUC of 0.7475 compared with 0.667 for TCAB, suggesting a favorable trend though the difference did not reach statistical significance.

However, drug use showed a lower P = 0.109, hinting at a possible trend, though it did not reach statistical significance.

Notably, Angle α and Angle β , which directly characterize the acuteness of the Cupid's bow apex, showed a decreasing trend post‐treatment (from 126.5° ± 14.0° to 120.8° ± 5.5°, and from 120.5° ± 10.9° to 116.6° ± 7.7°, respectively), though these changes did not reach statistical significance ( p > 0.05). 3.4 Different Age Group Lip Cases These three cases illustrate how identical treatments yield distinct outcomes based on age‐specific anatomical needs (Figures 5 , 6 , 7 ).

The standard-intensity group showed a trend toward increased risk, but this did not reach statistical significance (HR = 3.876, 95% CI: 0.846–17.758, P = 0.081).

Although MFN1 showed a trend toward increased expression with GDF15 treatment, these changes did not reach statistical significance.

Of note, the blastocyst formation rate exhibited a decreasing trend with higher TyG quartiles; in Q4 compared with Q1, the adjusted difference was − 2.37% points (β = − 2.37; 95% CI, − 4.78 to 0.03), which did not reach statistical significance, and other quartile contrasts were likewise non-significant.

Camre-chemo also showed a strong trend toward prolonged PFS (HR = 0.31, 95% CrI: 0.06–1.66), although this did not reach statistical significance due to wide credible intervals.

Compared to the ICL group, the PSS group showed a trend toward reduced microbial diversity; however, this difference did not reach statistical significance (Shannon index: p = 0.065; Simpson index: p = 0.066).

Kaplan–Meier analysis for overall survival showed a trend toward poorer survival in the high-risk group but did not reach statistical significance (log-rank p = 0.2; Fig. 10 C).

Serum RNASE1 levels were significantly higher in patients with severe disease activity compared with those with inactive disease, whereas patients with mild or moderate activity showed a trend toward increased RNASE1 levels that did not reach statistical significance ( Figure 2C ).

Short-term fasting (≤3 days; k = 15) showed a trend toward reduced triglyceride levels (g = −0.335; 95% CI: −0.684 to 0.013), although this effect did not reach statistical significance.

Correlation of PIK3CA mutations with outcome Patients enrolled in the G3 trial who had tumours with PIK3CA mutations showed a trend towards worse invasive disease-free survival (iDFS) compared to those with PIK3CA wild-type tumours, although this difference did not reach statistical significance (HR 2.1 (95%CI 0.95–4.78); p = 0.066) (Fig. 4 ).

Although OWDTO groups demonstrated a slight trend toward greater PTS increases, these differences did not reach statistical significance (Table 3 ).