These associations, however, did not reach statistical significance ( p < 0.05) after multiple testing correction which may be due to the limited statistical power from the small dataset (Additional file 1 : Tables S9 and S10).
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Moreover, NK1R antagonist pretreatment showed a tendency to enhance the effect of SP since the escape latency was somewhat lower compared to the SP-injected group; however, it did not reach statistical significance ( P = .050).
CC), the combined frequency of heterozygous and homozygous mutant genotypes (CG + GG) was 48.39% in cases and 40.32% in controls, but this difference did not reach statistical significance ( p = 0.05; OR = 1.39, 95% CI = 1.01 to 1.91).
The association between BRAF V600E mutation and age did not reach statistical significance (OR=0.66; 95% CI=0.43-1.00; P =0.05) ( Figure 2 A , Table 1 ).
As shown in the figure, the CI values of all muscles exhibited changes before and after the intervention; however, these changes did not reach statistical significance ( p < 0.05).
However, VL responses that remained > 1,000 c/mL approached but did not reach statistical significance for developing a first new AE (RR 2.34–4.41; p = 0.05–0.14) for each individual 12 month interval after initiating therapy (Table 2 ).
While the reduction with the 100 mg/kg dose did not reach statistical significance (20.18 ± 2.856 nmol/g), the MDA levels significantly decreased with both the 250 mg/kg and 500 mg/kg FA treatments (17.1 ± 2.257 nmol/g; p < 0.05, 16.42 ± 1.81 nmol/g; p < 0.05, respectively).
However, the revision surgery group showed a higher proportion of osteoporotic patients compared to the conservative treatment group, although the difference did not reach statistical significance ( p = 0.05).
TNSr did not reach statistical significance between groups; only clinical muscle strength showed pronounced weakness in the combined protocol ( P <0.05).
Higher rate of stent thrombosis was found in DOAC-based DAT versus TAT but did not reach statistical significance [1.4 versus 0.9% 1.51 95% CI (0.99–2.31) P = 0.05] [ Figure 4 ].
We found that while all mice in the control group (4/4) developed detectable tumors by day 17 that progressed rapidly thereafter, tumors in the IGF-Trap-treated group were only detectable in 1/5 mice at that time, and the growth rate in the majority of treated mice was lower than in the control group, although the difference under these experimental conditions did not reach statistical significance (defined as P ≤ 0.05) ( Figure 3B ).
greater resorption of the EMD was seen in the mock transfected group when compared to the miR-153 transfected group), the difference did not reach statistical significance ( P < 0.05).
Of those with high intent, 43.7% favoured vaccination at their HSCT programme, compared with 29.6% at their GP surgery although these findings did not reach statistical significance (p=0.05).
Prolonged hospitalization (>3 days) was more frequent among vitamin-deficient patients (OR = 2.63, 95% CI 0.99–6.93) and those with insufficient vitamin D (OR = 1.50, 95% CI 0.57–3.80), although these associations did not reach statistical significance ( p = 0.05 and p = 0.41, respectively).
There was a trend towards an increase in the proportion of patients classified as sarcopenic; however, this did not reach statistical significance (OR = 2.4, 95%CI = [1.0, 6.0]; p = 0.05).
A similar direction and strength of association between t1⁄2SmO 2 and both relative RCV and relative tHb mass was observed, although the latter did not reach statistical significance ( r = – 0.45; p < 0.05 and r = – 0.45; p = 0.06, respectively).
Though the interaction did not reach statistical significance, a preplanned Bonferroni post-hoc test found this effect to be primarily driven by a reduction in ethanol consumption during the first hour of testing ( p < 0.05).
Statistically significant improvements were observed in all parameters for both groups, although certain sub-parameters of postural oscillation in the TC group did not reach statistical significance ( p < 0.05).
However, this difference did not reach statistical significance ( P = 0.05).
Although the reduction in IPSS did not reach statistical significance at Day 30, it was mostly driven by a 30.7% decrease (p < 0.05) in the nocturia sub-score compared with baseline.
Across all three datasets, higher levels of the NFκB and AP-1 upregulated genes were generally associated with worse outcome although the outcome differences between the high/low dichotomized cases often did not reach statistical significance (p < 0.05).
Serum asprosin levels tended to be higher in patients without axillary lymph node metastasis; however, this difference did not reach statistical significance ( p = 0.050).
Although there was a trend suggestive of a modest cold anti-hypersensitivity at 2 h following the FN1040 injections, the difference did not reach statistical significance ( p < 0.05 compared with saline).
Comorbidities were reported in 18.2% of women in the NON-COVID-19 group, whereas 53.3% of women in the COVID-19 group had at least one comorbidity, although this difference did not reach statistical significance ( p = 0.05).
Although the effects of age and gender independently did not reach statistical significance in the likelihood of job change, the interaction between these two variables did show a significant effect (F = 3.376; p < 0.05), indicating, for instance, that younger men may be particularly prone to job changes in the short term, while older women are more likely to remain in their current roles.