However, in WT KRAS IHC‐positive samples we also observed difference between N cry and T2 ( p = 0.022) and a trend towards difference in staining intensity between the T1 and the T2; however, this did not reach statistical significance ( p = 0.050; Table 1 ).
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Later age of symptom onset (70+ years) was associated with lower odds of genetic testing completion (OR 0.23; 95% CI 0.12–0.43; P < 0.001) compared to the reference group (10–19 years), while early symptom onset (0–9 years) showed a trend toward higher odds of genetic testing completion that approached but did not reach statistical significance (OR 1.53; 95% CI 1–2.37; P = 0.05).
Although BDNF levels showed an increasing trend in the DLT-treated group, this change did not reach statistical significance ( p > 0.05; Fig. 2 E, F).
After confirming a successful silencing of TGFBR2 by using two independent shRNAs (shTGFBR2_B: ~42% decrease, P <0.0001; shTGFBR2_D: ~57% decrease, P =0.001), we saw a trend in lower intracellular TREM2 levels, although it did not reach statistical significance (shTGFBR2_B: ~16% decrease, P =0.05; shTGFBR2_D: ~19% decrease, P =0.09; Fig. 4 E middle panel, Fig.
Although downward trends with advancing age were observed for SOD1, SOD2, PRDX1, and SRXN1, these changes did not reach statistical significance, except for SOD2 in the 50–59 age group and SRXN1 in the 60–69 age group ( p < 0.05, Figure S2 ).
However, the adjusted hazard ratios (aHRs) for the comparison between the accelerated (Rabies+JE-Accelerated) and the conventional (Rabies+JE-Conventional) schedule did not reach statistical significance (p < 0.05), with aHRs of 1.34 (95% CI: 0.94–1.90, p = 0.1021) and 1.47 (95% CI: 0.98–2.22, p = 0.0620) in the FAS-2 and PPS-2, respectively ( Fig 4 and S2 Table ).
Additionally, SDNN and SD2, which indicate overall sympathetic and parasympathetic activity, were lower in the T1DM group but did not reach statistical significance ( p < 0.05).
Crucially, however, the analysis of variance revealed that the effects of the three tested factors—carbon source, nitrogen source, and inorganic salts—on the mycelial growth rate did not reach statistical significance at the p < 0.05 level.
Our findings show that although average concentrations of several autoantibodies were higher in CCP samples than in controls, most differences did not reach statistical significance, except for anti‐Ribosomal P autoantibodies ( p = 0.05).
However, the C group exhibited a higher relative abundance of Vibrio and Actinomyces species compared to the M group, although this difference approached but did not reach statistical significance ( p = 0.05).
Although there was a decreasing trend in triglycerides, it did not reach statistical significance (P>0.05).
Regions that did not reach statistical significance ( p < 0.05) included the FOrb (0.19 ± 0.27), hypothalamus (0.15 ± 0.45), and amygdala (0.18 ± 0.48).
Both PSI ICP and PSI B4C were the highest in patients after craniectomy, with PSI ICP being higher than PSI B4C , although this difference did not reach statistical significance ( p = 0.05) (see Fig. 4 ).
The multivariate regression modeling indicated that higher BMI and poor compliance were potential factors that might influence eradication outcomes, although these factors did not reach statistical significance ( P = 0.05).
Intervention patients were 1.77 (CI 0.94, 3.34, p = 0.078) times more likely than controls to be abstinent (12 versus 8%), a difference that approached, but did not reach statistical significance, and surpassed controls on number of days quit (18.4 versus 12.2, p < .05) but not on number of quit attempts.
It is noteworthy that in the GEO dataset, although the survival analysis results did not reach statistical significance ( P = 0.05), a trend was observed wherein patients in the high-risk stratification exhibited poorer survival outcomes (Fig. 3 C-D).
For vaccenic acid (18:1 n-7), the difference did not reach statistical significance ( p =0.05).
Although the difference in Mediterranean diet adherence scores between the groups did not reach statistical significance ( p = 0.050), a tendency toward higher adherence was observed among individuals without dementia.
PFS was also generally inferior in patients with elevated baseline CTCs, even though this finding did not reach statistical significance at the P < .05 level.
The risk of infection showed no significant associations with the TNF-α-238G>A and -863G>C SNP; carriers of the TNF-α-308A genetic variant were overrepresented among uninfected individuals, but the differences did not reach statistical significance (genotype comparisons, p = 0.05; allele comparisons, p = 0.07) (Table 2 ).
Osteopontin expression remained associated with RFS when corrected for age, sex and tumour site ( P =0.006), but after adjusting additionally for SNB status did not reach statistical significance at the P =0.05 level ( P =0.07).
30%) did not reach statistical significance (p < 0.05; chi-square and Fisher exact test), the relative risk and odds ratio for death were 1.83 and 2.85 times higher in open abdomen patients group.
However, this association did not reach statistical significance at the P <0.05 level.
No differences in survival were observed for patients treated with chemotherapy when stratified by Treg infiltration ( P = 0.565) CXCL12 expression does not differ between the different intrinsic subtypes, and is associated with longer survival Although a smaller proportion of basal-like (16/27, 59%) and HER2 tumours (25/47, 53%) was positive for CXCL12 expression compared with luminal tumours (102/138, 74%), this did not reach statistical significance ( P = 0.050) (Table 2 ).
Patients with LAA thrombus had a higher rate of MLVO (53% vs 40%) but this did not reach statistical significance ( p = 0.05; Table 1 ).