Barely Significant
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did not reach statistical significance

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In the literature

At the protein level, BDNF exhibited a trend of upregulation consistent with mRNA changes but did not reach statistical significance. p-TrkB protein levels were reduced in CRS mice ( p < 0.05 vs. control), and BDT treatment significantly reversed this decrease ( p < 0.01 vs.
a trend towards significancep > 0.051.0× alpha
showed a trendp > 0.051.0× alpha
did not reach statistical significancep > 0.12.0× alphaplainly factual
Both correlations were classified as moderate, and respectively did not reach statistical significance ( t = 1.89, df = 7, p > 0.1) or showed a trend towards significance ( t = 2.33, df = 7, 0.1 > p > 0.05).
Neuronal apoptosis in PVN specimens from model and sham-operated rats Immunochemistry, western blot and real-time PCR showed that cleaved caspase-3 and Bax amounts in PVN from model rats were significantly higher compared with the values obtained for sham-operated rats Bcl-2 expression was reduced in the model rats, both at the gene and protein levels, although the latter did not reach statistical significance (Figures 3A–D , p < 0.05).
Subgroup analyses based on different follow-up duration showed no significant differences at less than 3 months (WMD = −0.19; 95% CI: −0.84 to 0.46; p = 0.57) and at 3 months it showed a borderline improvement favoring punctal plugs, though this did not reach statistical significance (WMD = 1.72; 95% CI: −0.04 to 3.48; p = 0.05).
did not reach statistical significancep = 0.0511.0× alphaplainly factual
showed a trendp = 0.0511.0× alpha
In contrast, although patients with high miR-1321 expression showed a trend towards decreased overall survival, this association did not reach statistical significance ( p = 0.051), Overall, these findings indicate that increased expression of specific miRNAs is associated with unfavorable prognoses in glioma patients ( Figure 5 ). 4.