Barely Significant
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did not reach statistical significance

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In the literature

Efficacy ORR was 82.5% (95% CI, 76.9-87.2) in the once-weekly KRd56 group vs 86.3% (95% CI, 81.1-90.5) in the twice-weekly KRd27 group (risk ratio [once-weekly KRd56/twice-weekly KRd27] = 0.954 [95% CI, 0.882-1.032]; P = .0666; Table 2 ), which did not reach statistical significance for noninferiority at the prespecified alpha threshold of P ≤ .025, 1-sided.
It was also noted that the changes in several ABPM indicators of the ALI/AML group did not reach statistical significance compared to the AML group (except for changes in the daytime DBP between the two treatment groups, p = 0.0309).
In the present study, the effects of upper- and lower-body exercise trials on fat oxidation rates on day 2 were comparable, although differences between the lower-body exercise and control trials did not reach statistical significance (upper-body exercise trial: ES = 0.459, 95%CI 0.00 to 0.03, P = 0.031; lower-body exercise trial: ES = 0.436, 95%CI –0.03 to 0.00, P = 0.061).
The median decreases were 78.1%, 78.5% and 43.5% in patients with CR/VGPR, PR and PD, respectively, but the Kruskal–Wallis test on the three groups did not reach statistical significance possibly because of the high variability of the data, and the only faintly significant difference ( p = 0.0315) appeared between patients with CR/VGPR and those with PD when analysed separately by the Mann–Whitney test (Figure 2A ).
Although the anteroposterior thoracic diameter did not reach statistical significance in multivariate analysis, it still showed a similar trend for PPCs in univariate analysis (OR = 1.763, 95% CI: 1.050–2.961, p = 0.032), possibly due to a limited sample size.
Although CHA2DS2-VASc score categories did not reach statistical significance, a 1-point increase in the score was associated with a lower probability of favorable outcomes at 1 month (OR = 0.73, 95% CI 0.55–0.97, p < 0.033).
The magnitudes of mean UACR change from baseline with saxagliptin were greater in the eGFR < 30 and 30–50 ml/min/1.73 m 2 subgroups at − 245.2 mg/g and − 105.0 mg/g, respectively, although in the former subgroup it did not reach statistical significance; a smaller but significant improvement in UACR (− 19.3 mg/g; P = 0.033) was observed in the eGFR > 50 ml/min/1.73 m 2 subgroup [ 58 ].