Efficacy ORR was 82.5% (95% CI, 76.9-87.2) in the once-weekly KRd56 group vs 86.3% (95% CI, 81.1-90.5) in the twice-weekly KRd27 group (risk ratio [once-weekly KRd56/twice-weekly KRd27] = 0.954 [95% CI, 0.882-1.032]; P = .0666; Table 2 ), which did not reach statistical significance for noninferiority at the prespecified alpha threshold of P ≤ .025, 1-sided.
← all phrases
“did not reach statistical significance”
In the literature
did not reach statistical significancep -value = 0.025
We also found that CD14 monocytes (also known as classical monocytes) were expanded in the ALS blood, however, our analyses did not reach statistical significance after correction for multiple comparisons (fold change = 1.48; p -value = 0.025; adj. p -value = 0.36).
On the basis of protocol-prespecified Hochberg step-up multiplicity adjustment, the primary end point did not reach statistical significance ( P < .025).
They also showed more interest in constructive and creative activities such as model airplanes and Legos (48.93% vs 6.66%), although this difference did not reach statistical significance after applying the Bonferroni correction (p=0.025).
Gentle parents reported more satisfaction ( M = 4.15, SD = 0.96) than did non-gentle parents ( M = 3.73, SD = 0.92), although the difference did not reach statistical significance with the Bonferroni correction, t (98) = 2.26, p = 0.026.
At 0.55T, however, greater error for the ST segment did not reach statistical significance after Bonferroni correction (0.14 mV ST error vs. 0.07 mV PR error, p = 0.026).
Moreover, the HLA-DR score for UM with no-low pigmentation was lower than in moderately pigmented and heavily pigmented UM, even though the latter comparison did not reach statistical significance (no-low vs. moderate pigmentation: p = 0.027, no-low vs. heavy pigmentation: p = 0.053) ( Supplementary Figure S1e ).
While attendance at DBS-related activities did not reach statistical significance, a positive correlation was found between knowledge scores and specific DBS experiences, such as having referred a patient for DBS ( P = 0.028) ( Table 6 ).
did not reach statistical significancep = 0.0288
The interactions for time*trial ( F = 1.541, p = 0.2225), group*trial ( F = 4.158, p = 0.0556), and time*trial*group ( F = 0.192, p = 0.9421) did not reach statistical significance; however, there was a significant time*group interaction ( F = 2.863, p = 0.0288) (Figure 4c ).
When stratified by study design (RCT or OL), the CES of RCT studies tended towards symptom improvement; however, it did not reach statistical significance (Hedges g = 0.35, 95% CI = −0.04 to 0.74, p = 0.03, I 2 = 53.79%; Fig. 3 - Blue Dots).
In the 24-h social recall test, the preference of Tg(Kat6b) mice for a novel mouse over a familiar mouse did not reach statistical significance, whereas Kat6b +/+ mice showed the expected preference for the novel mouse ( p = 0.03; Figure 3 M).
While the difference in NPY expression between BP and PIN did not reach statistical significance, NPY EI was significantly higher in PCa than BP ( p = 0.03) and NPY expression in PIN did not differ significantly from invasive cancer ( p > 0.99, Fig. 6 ).
Although this did not reach statistical significance, when WAI variables were transformed to correct for skewness, the interaction was significant ( p = .03).
A similar trend was observed in AML (22.7% vs 18.7%; P = .58) but did not reach statistical significance in part due to the higher prevalence of seropositive RA in AML compared with MDS (78% vs 29%; P = .03), and the lack of association of seropositive RA with IDH mutation.
Children from middle SES families had lower alpha asymmetry (i.e., reduced right hemisphere alpha power) compared to low SES children, but this did not reach statistical significance ( p = .030).
did not reach statistical significancep = 0.0301
Even though the interim OS results of MONARCH-3 did not reach statistical significance (HR = 0.754, 95% CI 0.584–0.974, p = 0.0301), its absolute value is also very impressive, reaching 67.1 months.
did not reach statistical significancep = 0.0309
It was also noted that the changes in several ABPM indicators of the ALI/AML group did not reach statistical significance compared to the AML group (except for changes in the daytime DBP between the two treatment groups, p = 0.0309).
In the present study, the effects of upper- and lower-body exercise trials on fat oxidation rates on day 2 were comparable, although differences between the lower-body exercise and control trials did not reach statistical significance (upper-body exercise trial: ES = 0.459, 95%CI 0.00 to 0.03, P = 0.031; lower-body exercise trial: ES = 0.436, 95%CI –0.03 to 0.00, P = 0.061).
The result for SNP rs1063320 in human leukocyte antigen G ( HLA-G ) gene did not reach statistical significance after correcting for multiple testing (uncorrected one-sided p-value, p = 0.031; FDR-corrected one-sided p-value, p = 0.198) ( Table 2 ).
did not reach statistical significancep = 0.0315
The median decreases were 78.1%, 78.5% and 43.5% in patients with CR/VGPR, PR and PD, respectively, but the Kruskal–Wallis test on the three groups did not reach statistical significance possibly because of the high variability of the data, and the only faintly significant difference ( p = 0.0315) appeared between patients with CR/VGPR and those with PD when analysed separately by the Mann–Whitney test (Figure 2A ).
Although the anteroposterior thoracic diameter did not reach statistical significance in multivariate analysis, it still showed a similar trend for PPCs in univariate analysis (OR = 1.763, 95% CI: 1.050–2.961, p = 0.032), possibly due to a limited sample size.
did not reach statistical significancep = 0.0326
The differences shown in both scores did not reach statistical significance ( p = 0.0326 and p = 0.3526, respectively).
Although CHA2DS2-VASc score categories did not reach statistical significance, a 1-point increase in the score was associated with a lower probability of favorable outcomes at 1 month (OR = 0.73, 95% CI 0.55–0.97, p < 0.033).
The magnitudes of mean UACR change from baseline with saxagliptin were greater in the eGFR < 30 and 30–50 ml/min/1.73 m 2 subgroups at − 245.2 mg/g and − 105.0 mg/g, respectively, although in the former subgroup it did not reach statistical significance; a smaller but significant improvement in UACR (− 19.3 mg/g; P = 0.033) was observed in the eGFR > 50 ml/min/1.73 m 2 subgroup [ 58 ].
A cluster from SRT 82-184 ms showing the control curve higher than the PD curve also trended towards but did not reach statistical significance ( p = 0.034, cluster sum=105.67).