Barely Significant
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did not reach statistical significance

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In the literature

This outcome, whose individual components did not reach statistical significance, occurred in 35.5% of patients on treatment vs. 38.5% in the placebo group [relative risk (RR), 0.90; 95% confidence interval (CI), 0.82–0.98; P = 0.02]; 16.4% of patients on treatment and 17.5% of patients in the placebo arm died of cardiovascular causes (RR, 0.93; 95% CI, 0.81 to 1.06); 27.4% of patients on treatment and 29.6% in the placebo group were hospitalized for HF (RR, 0.90; 95% CI, 0.81–1.00).
Heart failure therapy: the fifth card.
Eur Heart J Suppl · 2023 · PMC10120986
Although SIRT1 levels were increased in the Se group compared to the control group, it did not reach statistical significance. In the CS group, an increase in Bax expression and a decrease in Bcl-2 and PGC1-α expressions were observed compared to the control group ( p = 0.023, p = 0.011, p = 0.003; respectively).
Efficacy ORR was 82.5% (95% CI, 76.9-87.2) in the once-weekly KRd56 group vs 86.3% (95% CI, 81.1-90.5) in the twice-weekly KRd27 group (risk ratio [once-weekly KRd56/twice-weekly KRd27] = 0.954 [95% CI, 0.882-1.032]; P = .0666; Table 2 ), which did not reach statistical significance for noninferiority at the prespecified alpha threshold of P ≤ .025, 1-sided.
It was also noted that the changes in several ABPM indicators of the ALI/AML group did not reach statistical significance compared to the AML group (except for changes in the daytime DBP between the two treatment groups, p = 0.0309).
In the present study, the effects of upper- and lower-body exercise trials on fat oxidation rates on day 2 were comparable, although differences between the lower-body exercise and control trials did not reach statistical significance (upper-body exercise trial: ES = 0.459, 95%CI 0.00 to 0.03, P = 0.031; lower-body exercise trial: ES = 0.436, 95%CI –0.03 to 0.00, P = 0.061).