When stratified by study design (RCT or OL), the CES of RCT studies tended towards symptom improvement; however, it did not reach statistical significance (Hedges g = 0.35, 95% CI = −0.04 to 0.74, p = 0.03, I 2 = 53.79%; Fig. 3 - Blue Dots).
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While the difference in NPY expression between BP and PIN did not reach statistical significance, NPY EI was significantly higher in PCa than BP ( p = 0.03) and NPY expression in PIN did not differ significantly from invasive cancer ( p > 0.99, Fig. 6 ).
Although this did not reach statistical significance, when WAI variables were transformed to correct for skewness, the interaction was significant ( p = .03).
A similar trend was observed in AML (22.7% vs 18.7%; P = .58) but did not reach statistical significance in part due to the higher prevalence of seropositive RA in AML compared with MDS (78% vs 29%; P = .03), and the lack of association of seropositive RA with IDH mutation.
Children from middle SES families had lower alpha asymmetry (i.e., reduced right hemisphere alpha power) compared to low SES children, but this did not reach statistical significance ( p = .030).
did not reach statistical significancep = 0.0301
Even though the interim OS results of MONARCH-3 did not reach statistical significance (HR = 0.754, 95% CI 0.584–0.974, p = 0.0301), its absolute value is also very impressive, reaching 67.1 months.
did not reach statistical significancep = 0.0309
It was also noted that the changes in several ABPM indicators of the ALI/AML group did not reach statistical significance compared to the AML group (except for changes in the daytime DBP between the two treatment groups, p = 0.0309).
In the present study, the effects of upper- and lower-body exercise trials on fat oxidation rates on day 2 were comparable, although differences between the lower-body exercise and control trials did not reach statistical significance (upper-body exercise trial: ES = 0.459, 95%CI 0.00 to 0.03, P = 0.031; lower-body exercise trial: ES = 0.436, 95%CI –0.03 to 0.00, P = 0.061).
The result for SNP rs1063320 in human leukocyte antigen G ( HLA-G ) gene did not reach statistical significance after correcting for multiple testing (uncorrected one-sided p-value, p = 0.031; FDR-corrected one-sided p-value, p = 0.198) ( Table 2 ).
did not reach statistical significancep = 0.0315
The median decreases were 78.1%, 78.5% and 43.5% in patients with CR/VGPR, PR and PD, respectively, but the Kruskal–Wallis test on the three groups did not reach statistical significance possibly because of the high variability of the data, and the only faintly significant difference ( p = 0.0315) appeared between patients with CR/VGPR and those with PD when analysed separately by the Mann–Whitney test (Figure 2A ).
Although the anteroposterior thoracic diameter did not reach statistical significance in multivariate analysis, it still showed a similar trend for PPCs in univariate analysis (OR = 1.763, 95% CI: 1.050–2.961, p = 0.032), possibly due to a limited sample size.
did not reach statistical significancep = 0.0326
The differences shown in both scores did not reach statistical significance ( p = 0.0326 and p = 0.3526, respectively).
Although CHA2DS2-VASc score categories did not reach statistical significance, a 1-point increase in the score was associated with a lower probability of favorable outcomes at 1 month (OR = 0.73, 95% CI 0.55–0.97, p < 0.033).
The magnitudes of mean UACR change from baseline with saxagliptin were greater in the eGFR < 30 and 30–50 ml/min/1.73 m 2 subgroups at − 245.2 mg/g and − 105.0 mg/g, respectively, although in the former subgroup it did not reach statistical significance; a smaller but significant improvement in UACR (− 19.3 mg/g; P = 0.033) was observed in the eGFR > 50 ml/min/1.73 m 2 subgroup [ 58 ].
A cluster from SRT 82-184 ms showing the control curve higher than the PD curve also trended towards but did not reach statistical significance ( p = 0.034, cluster sum=105.67).
In addition, the SOFAS score showed a discernible trend suggesting a potential association with the number of training sessions, although it did not reach statistical significance after FDR correction ( β = 0.246, CI = [0.043, 0.448], p = 0.034, pFDR = 0.070).
Through logistic analyses, we found that the association between serum lipid levels and the ORR did not reach statistical significance (Supplementary Table 1), but we found that LDL-C and non-HDL-C were reliable predictors of the DCR (HR: 16.309, 95% CI:1.207–220.326, p = 0.036; HR:34.484, 95% CI: 1.840–646.378, p = 0.018) (Supplementary Table 2).
Of note, the viral RNA load in the lungs of female mice was lower than that in male mice at comparable ages at 3 dpi, although the difference did not reach statistical significance except in 16-month-old mice ( p = 0.036) ( Figure 2B ).
Ruxolitinib treatment alone resulted in a 20% reduction in NHO volumes at day 7 and 35% at day 21, but this did not reach statistical significance by one-way ANOVA (significant by Mann-Whitney test at day 21 p = 0.037) ( Figures S6 C and S6D).
Considered individually, miR-320a-5p showed a statistically significant AUC score, while as miR-21-3p did not reach statistical significance (AUC = 0.647, p = 0.037 and AUC = 0.453, p = 0.058, respectively).
Although the results of the log-rank analysis did not reach statistical significance, the Wilcoxon analysis showed that SCs therapy had a positive impact on survival during the early stage of follow-up (P = 0.038).
The patency rates for fistula failures presenting with stenosis were slightly better than those presenting with thrombosis, but they did not reach statistical significance (67% vs. 52% at 12 months; P = 0.038).
3.67%), the difference did not reach statistical significance ( p = 0.039).
Subgroup analysis stratified by treatment regimen revealed that the same cutoff value predicted a trend toward longer survival in patients receiving combination therapy; however, the results did not reach statistical significance for OS (PFS: p = 0.04, OS: p = 0.06).
Adverse events and procedure times were lower in the FTRD ® group, although these differences did not reach statistical significance (4.44% vs. 15.5%, p = 0.04 and 25.6 ± 10.6 min vs. 76.7 ± 26.4 min, p ≤ 0.01).