Although the frequencies of binucleated cells and micronuclei did not reach statistical significance between groups, the DNA damage index (assessed by the comet assay; visual score; Figure 2 ) was significantly higher in the exposed group ( p < 0.001), supporting the genotoxic potential of Mancozeb in real-world occupational conditions.
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Hemoglobin levels (43.8 versus 65.3 g/L; P = 0.094) and hematocrit (14.3% versus 20.7%; P = 0.150) were lower in the autologous blood group, and white cell count was higher (0.15 × 10 9 /L versus 0.06 × 10 9 /L; P = 0.071), despite using identical volumes of PRBCs, but this did not reach statistical significance; platelet counts were however statistically lower in the banked blood group (45.0 × 10 9 /L versus 0.9 × 10 9 /L; P < 0.001).
SAT showed a decreasing trend in the highest tertile, although the between-group difference did not reach statistical significance. vBMD demonstrated consistent decreasing trend with rising TyG levels ( p < 0.001).
However, MR-Egger, simple mode, and weighted mode methods showed similar coefficient trends but did not reach statistical significance The CAUSE method further validated the causal relationship between Aβ accumulation and CSF pTau levels ( p =0.001).
C3a-desArg levels in the 4 mM citrate group tended to be lower as compared to the 3 mM citrate group, but the difference did not reach statistical significance (main effect of time p < 0.001, citrate group p = 0.107 and interaction effect p = 0.246).
Analysis of the little data available on endothelial function [ 11 , 12 , 34 ] seems to confirm a beneficial effect of continuous treatment with PDE5i, although the data were almost entirely derived from ED patients [ 54 , 55 ], the effects did not reach statistical significance in patients with left heart disease, and there was very high heterogeneity (I 2 = 99%, P <0.001).
Although this difference did not reach statistical significance, a significant main effect of time was observed (F(1, 28) = 15.00, p < 0.001, ηp 2 = 0.349; Figure 6 ), accompanied by a moderate effect size.
For AVR and AVT, between-group comparisons did not reach statistical significance, though the observation group showed changes in AVR ( P = 0.001) and AVT ( P < 0.001) compared to their own baseline measurements ( Figure 3 ).
Effects of VIL and NWT-03 supplementation in ZDF rats ( Table 2 ) GLP-1 levels trended higher (∼1.4-fold) after NWT-03 treatment (although this difference did not reach statistical significance), and were profoundly increased (∼5-fold, p<0.001) by VIL.
However, specific organ affection by systemic emboli did not reach statistical significance between groups, with the exception of pulmonary embolism, associated with Staphylococcal IE ( p = 0.001).
Although the improvement in NRI compared to the APPLE score in the training cohort did not reach statistical significance, the nomogram significantly outperformed the three scores on all metrics in the validation cohort (all P < 0.001).
However, after two-stage propensity score calibration ( Table 4 ), the impact of SAMA on stroke risk did not reach statistical significance, while the adjusted HR for stroke was increased to 1.67 (95% CI 1.45–1.91, p < 0.001) with the use of SABA.
The analyzed group of new-borns did not reach statistical significance, 108 out of 113 new-borns (first 28 days of life) showed no discrepancies and only five cases were discrepant (P < 0,001).
For all three markers, we found higher levels of staining extent in dense as compared to non-dense tissue, though for CD24 and ALDH1A1 the difference did not reach statistical significance (CD44, 6.3% vs. 2.0%, p < 0.001; CD24, 8.0% vs. 5.6%, p = 0.10; and ALDH1A1, 0.5% vs. 0.3%, p = 0.12).
borderline significancep = 0.055
Significant differences were observed between Grade 2 and Grade 4 in VAS ( p = 0.013), ICOAP-constant pain score ( p = 0.041), ICOAP-total score ( p = 0.047), TUG ( p = 0.025), and KOS-ADLS ( p = 0.055, borderline significance), while quadriceps muscle strength of the affected knee did not reach statistical significance in this comparison ( p < 0.001 indicates strong significance depending on direction) (Table 3 ).
3 E), while GFAP did not reach statistical significance ( R = 0.532, p < 0.001, Fig. 3 F).
The survival of EP patients was better than EPC patients but did not reach statistical significance and, in the Cox multivariate analysis only age had statistically significant effect (HR 1.061, 95% CI 1.026–1.099, p < 0.001).
did not reach statistical significancep = 1.2 ⋅ 10 -3
A slight downregulation of AT5G17700 in atml1 mutants (1.9-fold higher expression in Col_WT versus atml1 ) did not reach statistical significance ( p = 1.2 ⋅ 10 -3 , but padj = 1 after multiple testing correction).
did not reach statistical significancep = 0.0012
In the spleen, while there was a general tendency for the increase in parasite burden between day 15 and day 60, in the case of IMT-151 this increase (0.3 log on average) did not reach statistical significance, while ITMAP-263 and IMT-202 exhibited a 0.7 log increase in spleen parasite burden in the same time interval ( p = 0.0012 and p = 0.0008 between day 15 and day 60, respectively for each parasite strain) (Fig. 3b , d and f ).
did not reach statistical significancep = 0.0014
When comparing the caudal directed CSF velocities, we found an increase of 2–11% in caudal iCSF which did not reach statistical significance, and a decrease of 43–78% in caudal rCSF velocity with statistical significance for DAB (78%, p = 0.0014) and DDB (68%, p = 0.0074).
did not reach statistical significanceP = 0.0014
Protein episcores and CRC overall survival In Cox regression models adjusted for age at diagnosis, the Protein EpiScores for LGALS3BP and VEGFA appeared associated with higher mortality risk, but these associations did not reach statistical significance after adjustment for multiple comparisons (LGALS3BP, HR: 1.61, 95% CI 1.20, 2.15, P = 0.0014, FDR = 0.15; VEGFA, HR: 1.62, 95% CI 1.20, 2.19, P = 0.0016, FDR = 0.17) (Fig. 3 ).
did not reach statistical significancep = 0.001482
In the SM group of patients, this allele is also more prevalent, but the association did not reach statistical significance ( p = 0.001482, Table 2 ).
did not reach statistical significancep = 0.0018
In adjusted Cox regression analysis, children 6–10 years had a higher mortality risk compared with infants but did not reach statistical significance (adjusted HR 7.33, 95% CI 2.09–25.68, p = 0.0018) (Table 3 ). 4.
did not reach statistical significancep < 0.0019
aureus isolates for all sample types except for biopsies and other samples, for which the p-value did not reach statistical significance after adjustment for multiple testing (i.e. p < 0.0019) (Fig. 1 , lower panel).
did not reach statistical significancep = 0.0019
Other women also had higher rates of positive TBI screen on the BTBIS than White women; however, differences did not reach statistical significance after correction for multiple comparisons (26.4% vs. 15.1%, p = 0.0019).