Barely Significant
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“did not reach statistical significance”

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Although the frequencies of binucleated cells and micronuclei did not reach statistical significance between groups, the DNA damage index (assessed by the comet assay; visual score; Figure 2 ) was significantly higher in the exposed group ( p < 0.001), supporting the genotoxic potential of Mancozeb in real-world occupational conditions.
Hemoglobin levels (43.8 versus 65.3 g/L; P = 0.094) and hematocrit (14.3% versus 20.7%; P = 0.150) were lower in the autologous blood group, and white cell count was higher (0.15 × 10 9 /L versus 0.06 × 10 9 /L; P = 0.071), despite using identical volumes of PRBCs, but this did not reach statistical significance; platelet counts were however statistically lower in the banked blood group (45.0 × 10 9 /L versus 0.9 × 10 9 /L; P < 0.001).
Analysis of the little data available on endothelial function [ 11 , 12 , 34 ] seems to confirm a beneficial effect of continuous treatment with PDE5i, although the data were almost entirely derived from ED patients [ 54 , 55 ], the effects did not reach statistical significance in patients with left heart disease, and there was very high heterogeneity (I 2 = 99%, P <0.001).
Significant differences were observed between Grade 2 and Grade 4 in VAS ( p = 0.013), ICOAP-constant pain score ( p = 0.041), ICOAP-total score ( p = 0.047), TUG ( p = 0.025), and KOS-ADLS ( p = 0.055, borderline significance), while quadriceps muscle strength of the affected knee did not reach statistical significance in this comparison ( p < 0.001 indicates strong significance depending on direction) (Table 3 ).
In the spleen, while there was a general tendency for the increase in parasite burden between day 15 and day 60, in the case of IMT-151 this increase (0.3 log on average) did not reach statistical significance, while ITMAP-263 and IMT-202 exhibited a 0.7 log increase in spleen parasite burden in the same time interval ( p = 0.0012 and p = 0.0008 between day 15 and day 60, respectively for each parasite strain) (Fig. 3b , d and f ).
Protein episcores and CRC overall survival In Cox regression models adjusted for age at diagnosis, the Protein EpiScores for LGALS3BP and VEGFA appeared associated with higher mortality risk, but these associations did not reach statistical significance after adjustment for multiple comparisons (LGALS3BP, HR: 1.61, 95% CI 1.20, 2.15, P = 0.0014, FDR = 0.15; VEGFA, HR: 1.62, 95% CI 1.20, 2.19, P = 0.0016, FDR = 0.17) (Fig. 3 ).
aureus isolates for all sample types except for biopsies and other samples, for which the p-value did not reach statistical significance after adjustment for multiple testing (i.e. p < 0.0019) (Fig. 1 , lower panel).