“did not reach statistical significance”

Of five cell lines tested (IGROV1 cells did not form spheroids at all), we observed significantly increased numbers of spheroids in the SP fraction of four models (i.e., A2780, A2780V, B16/92, B17/92), whereas in the fifth cell line (i.e., B2/92) we could only detect a slight trend that did not reach statistical significance (Fig. 3C + 3D).

In this study, glycopyrronium showed a trend towards reduction in the risk of exacerbation both in terms of rate and time to first moderate and severe COPD exacerbations, although this finding did not reach statistical significance.

The association of the area of RPE atrophy with SYN 3 showed a trend, but did not reach statistical significance ( p = 0.07).

A permanova-based test showed a trend toward a difference between all EoE and non-EoE control esophageal samples in community proportions which did not reach statistical significance (weighted UniFrac distances; Adonis P values for EoE versus non-EoE control subjects: P = 0.06).

The kinetics of inactivation for the E443A and E443A-E445A-E447A mutant channels demonstrated a strong trend to decrease the inactivation rate but did not reach statistical significance.

Although a numerical trend indicated that the ear contralateral to the lesion scored more poorly than the ear ipsilateral to the lesion did, this difference did not reach statistical significance ( Table 3 ).

64 – 66 One such study showed a trend toward improvement in insulin sensitivity after CPAP therapy using the hyperinsulinemic–euglycemic clamp; however, the degree of improvement did not reach statistical significance. 67 It is possible that the failure to obtain a statistically significant result was because mean nightly usage of CPAP in that study was only 3.6 hours.

Recently, one study found that the presence of NAFLD showed a favorable trend on survival rates in CRC patients, although the data did not reach statistical significance ( P = 0.079), perhaps in part due to the small number of patients (227 patients) and poor statistical power. 20 Therefore, we aimed to design a large and more statistically robust cohort study to investigate the impact of NAFLD on the prognosis of patients with CRC.

However, analyses revealed a positive trend that did not reach statistical significance for either pCR or tpCR.

The wild-type 7D8 showed a trend of activity, but did not reach statistical significance compared to controls.

Sensitivity analysis for unobserved confounding The difference-in-difference analysis showed a trend towards more emergency admissions among intervention patients than controls, but the effect size was smaller than in the primary analysis and did not reach statistical significance (difference 0.10 admissions per head, 95% CI −0.06 to 0.26, p=0.220) (see online supplementary table S1 and figures S1 and S2).

Expression of CD32 on CD141 + DCs showed a decreasing trend already after 8 weeks, but this change did not reach statistical significance (p = 0.0651; S3 Fig ).

The corresponding OR of failure of SLNM showed a trend with 3.8, but Chi-Square test did not reach statistical significance in this subset of patients (p = 0.09).

Finally, the counts of lymphocytes and white blood cells showed a slight trend to diminution, but the final effect with this limited number of subjects did not reach statistical significance ( Fig 4C ).

Endothelin System Genes Expression in Lungs and Heart Lung and heart preproET-1 mRNA levels exhibited an increasing trend 2h after exposure at the highest dose of AEOL 10150, but the changes did not reach statistical significance ( Fig 3A and 3B ).

ROS production was also reduced, except in control and IL-10-treated cells, where the CRAC blocker showed a trend toward a decrease that did not reach statistical significance.

There is a clear trend toward increased complication rates when thicker ADMs were chosen; however this did not reach statistical significance.

During the three months follow-up, there was a notable trend of lower mortality in patients who received a cementless THA (8.8%) compared to the cemented group (16.5%), but it did not reach statistical significance ( p = 0.06).

While the difference in reactivity to K5Me2 between SLE patients with high and low IFN signatures did not reach statistical significance by ELISA, there was still a strong trend toward greater reactivity in patients who had high IFN signatures.

The patients tested on the binocular rivalry task showed a pattern of percept duration distributions that was similar to their performance on the SFM task ( figure 5 c ), and the mean percept durations for all three bistable stimuli showed a trend towards being correlated with each other, although this did not reach statistical significance (rotating sphere-binocular rivalry, r = 0.61; rotating sphere-dot quartet, r = 0.13; figure 5 d ).

Using the NCEP ATP III criteria, there was a strong trend of higher proportion of MS (44.15%) in COPD as compared to non-COPD (31.16%); however, the difference did not reach statistical significance ( P < 0.096).

Also, there was a strong trend for higher numbers of cFos+ neurons in the BLA in the Ext-RC group as compared to the Ext-Ext group ( Figure 3C ), but this did not reach statistical significance.

In the 500 IR group, all main and subdomains showed a trend of improvement but did not reach statistical significance.

Hepatic iron content was higher than humanized controls in control thalassemia and iron-loaded animals while splenic iron showed an increasing trend but the results did not reach statistical significance.

However, immigrant children showed a trend toward a higher proportion of both TST positivity and active TB, even though the latter did not reach statistical significance likely due to the small sample size.