Endothelial function showed a trend towards improvement but did not reach statistical significance (max. dilation p = 0.072), whereas the pulse wave velocity, a marker for the vessel stiffness, decreased significantly in the intervention group.
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“did not reach statistical significance”
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a clear trendgold
SP-A showed a clear trend, but the difference in SP-A levels between NPH subset and control group did not reach statistical significance ( p = 0.052).
The children with active disease showed a trend toward higher numbers of time-intensity-curve shapes 3 and 4 compared to the children with inactive disease, but did not reach statistical significance ( P = 0.310 and P = 0.166).
Expression of the Gal ABC transporter spd_0088 gene showed a trend identical to that of the Leloir pathway genes, but the differences did not reach statistical significance ( Fig. 7A ).
There was an overall trend toward a higher percentage of patients reaching the primary end points in the CEST group, but the differences did not reach statistical significance.
5 , 6 , 24 Although it did not reach statistical significance, we noted a nonsignificant trend toward fewer complications among our MIE patients.
Another non-randomized study showed a trend toward mortality benefit with liposomal doxorubicin as compared to bleomycin plus vinblastine, vincristine or ARV monotherapy alone, although this did not reach statistical significance[ 52 ].
The proliferation showed a trend to correlation with patch test score (Figure 1 B) although there was substantial variability in the proliferation observed in patients with high score, such that the correlation did not reach statistical significance with this number of patients.
Although an increasing trend can be observed in DRD1 and DRD2, it did not reach statistical significance.
Patients in the higher risk stratum of the CARRS score showed a trend towards lower survival, but this did not reach statistical significance (p = 0.411, Fig. 2 ).
While patients with higher expression of both BMI1 and CK2α showed a trend towards shorter progression free survival, the data did not reach statistical significance likely due to the limited sample size (Additional file 1 : Figure S2).
However, these recommendations were based mainly on 3 studies: a single randomized trial [ 22 ] which had a high risk of bias by the Cochrane risk assessment tool; a meta-analysis by Berger et al [ 7 ] that showed a trend of reduction in the composite of MI, nonfatal stroke, and cardiovascular death with aspirin that did not reach statistical significance; together with older evidence from the Antithrombotic Trialists’ Collaboration (ATC) meta-analysis [ 4 ].
However, immigrant children showed a trend toward a higher proportion of both TST positivity and active TB, even though the latter did not reach statistical significance likely due to the small sample size.
Results of the qualitative analysis did not reach statistical significance for the motivational and learning decision making components considered, but approached significance for the attentional component for elderly versus young normals, suggesting a possible decrease in the ability to maintain sustained attention during complex and prolonged tasks as the putative deficit underlying impaired decision making in normal aging.
Although cortisol concentrations during the ACTH test showed a trend towards decrease after seven days, they did not reach statistical significance.
The mtp53 cell line BE showed a trend toward Nutlin-3-dependent IGF-1R degradation in the presence of IGF-1 but only displayed a 20% decrease at 1 μ M Nutlin-3 concentration, which did not reach statistical significance.
Although SERCA activity showed a trend toward inhibition in diabetic human VSM cells, this did not reach statistical significance ( Figure 9(e) ).
Redirected splicing resulted in a significant prolongation of twitch half relaxation time and a strong trend toward increased peak twitch force and peak calcium, although these changes did not reach statistical significance ( Figure 9C ).
Higher epithelial GLI3 expression in the tumor showed a trend towards a better prognosis although this did not reach statistical significance in this cohort ( p = 0.092) (Fig. 4 ).
In the beating-heart CPB and off-pump technique groups, the levels of troponin I had an increasing trend post-surgery, but did not reach statistical significance.
We observed a slight trend towards lower PTH rates in the TE mic group but the differences did not reach statistical significance.
Results showed a trend for improved OAS in patients treated with metformin vs the controls, which approached but did not reach statistical significance ( p = 0.06).
Interim OS showed a trend in favor of T-VEC; HR 0.79 (95% CI 0.61, 1.02) which did not reach statistical significance.
One‐year mortality did not reach statistical significance, although a positive trend towards a reduction with levosimendan was noted.
Another systematic review by the same author addressed the effectiveness of supplementation on ROP and found a positive trend towards a beneficial effect, although it did not reach statistical significance [ 52 ].