“did not reach statistical significance”

While combined methods showed a trend toward improvement (RR = 1.06, 95% CI: 0.98–1.15), this did not reach statistical significance (P = 0.657), with no heterogeneity (I2 = 0%).

Although a strong trend of increase was shown for platelet rGSK‐3β(T/S9), the difference did not reach statistical significance between T2DM‐MCI and T2DM‐nMCI groups (GSK‐3β‐Total: p = 0.760; GSK‐3β: p = 0.237; rGSK‐3β: p = 0.122) (Figure 3a‐c ).

However, there was a slight trend in the favoring paracetamol over indomethacin in terms of primary PDA closure [RR, 1.01 (95% CI, 0.91–1.12), P = 0.88] and overall PDA closure [RR, 1.02 (95% CI, 0.94–1.11), P = 0.88] ( Table 6 ), but the difference did not reach statistical significance.

While copper showed a positive trend toward association with T2D risk, it did not reach statistical significance ( P = 0.922).

Urinary incontinence outcomes did not reach statistical significance; however, a positive trend was observed.

Post hoc analysis indicated that CEM at 100 μL/L significantly increased the number of arm entries ( p < 0.01), while CEM at 150 μL/L showed a trend toward improvement that did not reach statistical significance ( Figure 1 B).

And the gene expression levels of Cxcl12, Flt1, and Kdr were also significantly increased in the P-EVs group compared with the EVs group ( P < 0.05), while Tgfbr1 also showed an increasing trend, though this did not reach statistical significance (Figure 7 E).

Likewise, the corn cereal group demonstrated a decreasing trend in GQ values from baseline (85.39 ± 11.98) to post-intervention (78.26 ± 12.42), although this difference did not reach statistical significance ( p = 0.060).

Serum OPN concentrations also showed a trend toward being lower in patients with decreased ALM/W index values, although this difference did not reach statistical significance ( p = 0.060). 4.

After excluding patients with mantle cell lymphoma, we analyzed OS in the remaining 409 patients with indolent NHL: the patients in the high BMI group showed longer OS with 85.0% of patients alive at 5 years versus 70.2% in the low BMI group (HR 0.581; 95%CI 0.331–1.022; p = 0.059). Of interest, there was a slight trend for longer PFS in the high BMI group when compared to the low BMI group, which however did not reach statistical significance (HR 0.798; 95%CI 0.586–1.087; p = 0.152), with 42.5% of patients without progression after 5 years in the high BMI group versus 32.9% in the low BMI group (Fig. 1 b).

As shown in Figures 6d and 6e , lysosomes from nfe2l2 -KO mice showed a trend toward reduced RNASE uptake in comparison with Nfe2l2 -WT littermates, although it did not reach statistical significance.

Survival analysis showed a trend toward decreased overall survival in patients with tumors located in eloquent areas compared to non-eloquent areas, although this difference did not reach statistical significance. 3.5 Correlations Normal distribution was tested using the Kolmogorov-Smirnov test, and age and VtFLAIR were found to be normally distributed ( Fig.

Further subgroup analysis by clinical diagnosis and CRP levels showed a trend toward increased antibiotic use in children with ARI and AFI when CRP was elevated, although these did not reach statistical significance.

The GluN2A subunit also showed a trend toward a decrease, but this difference did not reach statistical significance.

Compared with the baseline data, we found that the CD8 + T-cell percentage (paired t test, P = 0.5063) and CD45RO + CD8 + T-cell percentage (paired t test, P = 0.5319) showed an increasing trend, but the difference did not reach statistical significance (Fig. 3 A, B ).

Analysis of the complete blood count showed a trend toward reduced circulating monocyte and neutrophil counts with BHB treatment; but these differences did not reach statistical significance.

AS alone resulted in weight loss comparable to sham and TBI alone, whereas the combination of TBI + AS showed a numerical trend toward nearly doubled weight loss compared with single AS or TBI exposure; however, this difference did not reach statistical significance (Fig. 4 A).

The expansion of activated memory B cells observed at M2 negatively correlated with CD4 T-cell frequency (p = 0.022), positively correlated with CD8 T-cell activation (HLA-DR+CD38+ cells, p = 0.033), and showed a positive trend with VL that did not reach statistical significance.

Although the difference between the combined model and the SAA kinetics model at 12 months did not reach statistical significance, the p value was borderline (0.051), suggesting a strong trend toward improved prediction.

NP-led MET calls showed a trend toward decreased mortality within 24 h of index MET call, but this did not reach statistical significance (3.4% vs. 7.2%, 0.47 (0.21–1.05); p = 0.06).

However, according to CAP, GLP-1RAs only showed a trend of better effects than TZDs and did not reach statistical significance.

In the multivariable Cox regression analysis, PAL showed a trend toward an increased risk of severe exacerbations (adjusted hazard ratio (aHR), 1.81; 95% CI, 0.99–3.32), although this did not reach statistical significance ( Table S7 ).

Epinephrine showed a trend toward association with SA-AKI, though it did not reach statistical significance ( p = 0.067). 3.2.

In the complete case analysis, long shifts showed a trend toward increased sleep-aid use but did not reach statistical significance (OR 1.64, 95% CI 0.99–2.66) ( Data Supplement 3 ).

Although symptom duration < 24 h and age > 75 years showed a trend toward increased odds of successful conservative management, these associations did not reach statistical significance. 4.