“extremely significant”

The tumor size and weight of the H + AB@Cu-MOF + NIR group were significantly lower than those of all other groups with extremely significant differences compared with the control group (*** p < 0.001), which fully proves that AB@Cu-MOF nanocomposite hydrogels can achieve prominent synergistic enhancement of PTT-TDT-CDT under NIR irradiation and greatly improve in vivo anti-tumor efficacy.

Student’s t -test was used for the statistical analysis, and a value of P < 0.05 was considered statistically significant (*), P < 0.01 as highly significant (**) and P < 0.001 as extremely significant (***). .

The results showed that the difference is extremely significant (F = 5.925, p<0.001) (see Table 2 ).

Statistical differences are considered significant at a p < 0.05 significance level and marked with “∗”, very significant at p < 0.01 and labeled with “∗∗”, and extremely significant at p < 0.001 and labeled with “∗∗∗”.

While supplementation of aqueous rosemary extract with acrylamide led to an extremely significant increase in body weight with age ( P <0.001) when compared with acrylamide-treated rats.

Extremely significant differences were found in the mRNA expression levels of FSHR ( P = 0.001), IGF-1R ( P = 0.001), and CYP19A1 ( P = 0.001) between the 2.5% dose group and the control group ( P < 0.01), and no difference was found between the 2.5% dose group and the NOR group.

Two-sided p values less than 0.001 were regarded as statistically extremely significant (*** p < 0.001).

Additionally, concentrations of 5 mg/L and higher for more than 4 days exhibited a significant inhibitory effect on the growth of Foc TR4 mycelia, with the inhibitory effect being extremely significant at concentrations of 40 mg/L and higher ( p < 0.001).

Differences were considered statistically significant at * p < 0.05, very significant at ** p < 0.01, extremely significant at *** p < 0.001, and very extremely significant at **** p < 0.0001.

The percentages of IDS activity expressed in transfected COS-7 cells of individual novel missense mutations for c.137A>C, c.311A>T, c.454A>C, c.797C>G, c.817C>T, c.998C>T, c.1106C>G, c.1400C>T, c.1402C>T, and c.1403G>A ranged from 0% to 2.2%, and were extremely significant compared to the wild type ( p <0.001).

“*” represents significant ( P < 0.05), “**” represents very significant ( P < 0.01), and “***” represents extremely significant ( P < 0.001). 3.

Boosting with VLPs resulted in increased antibody titers, with final antibody titers reaching extremely significant (p< 0.001) values over the negative control mice.

The difference between means is significant if p value < 0.05 (*), very significant if p value < 0.01 (**), extremely significant if p value < 0.001 (***) or if p value < 0.0001 (****).

For a differential characterization the following additional designations were chosen: p ≤ 0.01: highly significant; p ≤ 0.001: extremely significant.

The positive control, 160 μM MMS, induced an extremely significant (p < 0.001) genotoxic effect compared to the control group with a TAU mean value of 554.2 ± 9.9.

Distance to old oil palm plantations is an extremely significant variable (p < 0.001) having a negative effect on forest conversions to oil palm plantations during both time periods (pre-2000 and post-2000) and could be considered the most important determinant of forest conversion to oil palm plantations.

In contrast, the group treated with silymarin showed extremely significant ( P < 0.001) decreases in direct bilirubin, SGOT, SGPT and ALP values toward normalization.

However, statistical analysis showed the differences between PTSm and PTX, PTX + S-HM-3 and PHTSm were significant ( P <0.05), while that of PTX and PHTSm was extremely significant ( P <0.001).

The strength of statistical significance was defined using the following thresholding system: ns (Not significant): p ≥ 0.05, * (Significant): 0.01< p < 0.05, ** (Very significant) 0.001< p < 0.01, *** (Extremely significant) 0.0001< p < 0.001, **** (extremely significant) p < 0.0001.

Similarly, BLG was the major allergen for serum number 9 and 10 with extremely significant differences ( *** P < 0.001); it was also one of allergens for serum number 7, 8 and 11 with varying degrees of differences (serum number 7 and 11, * P < 0.05; serum number 8, ** P < 0.01).

On the regression model, was extremely significant (P < 0.001), but the ANOVA for lack of fit was insignificant (P > 0.05).

It can also be subdivided into three groups, such as 2-Vinyl-4H-1, 3-dithiine and allyl methyl disulfide were extremely significant positive correlation with W5C and W3C ( p < 0.001), this analysis was similar to the research results of Guo et al.

10 The overall meta-analysis study was extremely significant with a P value < 0.001 with a pooled estimate of 7.987 and CI (5.334, 10.639), confirming the significance of the results and the presence of the real effect of the use of the particulate systems on the pharmacodynamic responses of the investigated drugs, as revealed by AUEC.

It was further differentiated between extremely significant (***, p < 0.001), very significant (**, p = 0.001 to 0.01) and significant (*, p = 0.01 to 0.05) results.

The statistical analysis of independent sample t-tests revealed that compared with the baseline YOLOv5s, all four key metrics of the improved model showed extremely significant differences ( p < 0.001), and the large effect sizes (Cohen’s d = 4.29–6.82) indicated strong practical significance.