“highly significant”

An identical and highly significant pattern ( p < .001 for all inter-group comparisons) was observed for F. nucleatum (SDF: 6.33% ± 0.58%; CHX: 33.33% ± 4.73%; PBS: 75.67% ± 8.74%), A. actinomycetemcomitans (SDF: 6.67% ± 1.53%; CHX: 29.33% ± 4.04%; PBS: 83.33% ± 7.37%) and the multi-species biofilm (SDF: 8% ± 1.00%; CHX: 31.33% ± 2.52%; PBS: 74.67% ± 6.66%).

Although ADAS‐Cog scores in the metformin group improved from 16.9 ± 6.1 at baseline to 11.9 ± 3.7 at the 1‐year endpoint ( p < 0.001), the difference between the two treatment arms was highly significant ( p < 0.001), as no comparable benefit was observed in the acarbose–donepezil group (17.0 ± 5.9 to 15.9 ± 3.9, p = 0.295). 15 Daphnetin is a natural coumarin derivative with multiple pharmacological activities, including antioxidant, anti‐inflammatory, and anti‐apoptotic effects. 16 It provides “triple protection” for the blood, vascular endothelium, and ischemic tissues by inhibiting inflammation, anticoagulation, and thrombosis; preserving endothelial integrity; and regulating vasoactive substances.

Regarding soil properties, soil As content exhibited a highly significant positive correlation with CEC ( p < 0.001), and significant positive correlations with gravel (volume percentage), clay, calcium carbonate (CaCO 3 ), water-soluble nitrogen (WSN), distance to habitation (DH), silt, and TEB ( p < 0.01 or p < 0.05).

14 , 15 DM, by contrast, was characterized by near-universal skin involvement (100%) with Gottron papules in 83.3% and heliotrope rash in 41.7% — findings highly significant across subtypes (p < 0.001) and clinically valuable for early subtype identification at bedside.

The association between PNI and NKX3.1 staining score was highly significant (chi-square = 17.731, p < 0.001; Cramer V = 0.558).

The relative direct effect was also significant ( c’ 2 = 0.751, p = 0.008), and the relative total effect was also highly significant ( c 2 = 1.761, p < 0.001).

Variations in amino sugars and MNC content in soil LMM analysis showed that land-use type had a highly significant main effect on all four amino sugars ( p < 0.001), whereas soil depth alone had no significant main effect on any of them.

Comparisons between exposed populations and controls were highly significant ( p < 0.001) for Sedayu and Kemejing, significant for Kembaran ( p = 0.001), and Wadas showed no significant difference ( p = 0.297), indicating limited exposure (Table 4 ; Fig. 5 ).

Moreover, a highly significant association was observed between higher bipolar voltage and a greater prevalence of ROIs, including both rotational and focal activities ( p < 0.001), and between a higher percentage of vLVZs and fewer ROIs and fewer focal/rotational activities ( p < 0.001).

A highly significant, moderate positive scaling was observed between HIR and the ultimate 90-day mRS score (r = 0.496, p < 0.001; Figure 3A ).

Highly significant main effects of PGR type (df = 2, Wald χ2 = 20538.041, P < 0.001; df = 2, Wald χ2 = 75.219, P < 0.001; df = 2, Wald χ2 = 1961.779, P < 0.001) and PGR concentration (df = 3, Wald χ2 = 7854.678, P < 0.001; df = 3, Wald χ2 = 186.271, P < 0.001; df = 3, Wald χ2 = 1570.579, P < 0.001) were detected for callus induction rates.

Keywords dairy farm milk-quality milk-yield vaccine-coverage NORAD RADO/EXTERNAL/SS0027/2024 However, a highly significant association was found between current vaccination status and the immediate effect of vaccination on milk yield, as confirmed by Fisher’s exact test ( p < 0.001), and the relationship between prior vaccination and the perceived change in milk yield postvaccination was also statistically significant ( χ 2 = 32.67, p < 0.001), as shown in Table 3 . 3.3.

Statistical significance levels were defined as follows: p > 0.05 (ns; not significant), p < 0.05 ( significant), p < 0.01 ( highly significant), and p < 0.001 ( extremely significant). 3.

Within-group improvements were highly significant in both groups (Group A, nab-paclitaxel: baseline vs 6 m p = 0.001, baseline vs 12 m p = 0.001, 6 m vs 12 m p = 0.001; Group B, sb-paclitaxel: baseline vs 6 m p = 0.001, baseline vs 12 m p = 0.001, 6 m vs 12 m p = 0.01).

Panel C reveals a concentration of strong correlations near r ≈ ±1 with corresponding significance thresholds; several life histories have highly significant r values ( p < 0.001).

The optimal SARIMA model describing the monthly time series also supported a significant 12-month seasonal pattern: the seasonal autoregressive term (estimate ± SE = − 0.37 ± 0.10) was highly significant ( p < 0.001).

The test of moderators revealed a highly significant effect of region (Test of moderators, p < 0.001).

Although the acetone and ethanol extracts resulted in slightly lower larval mortality rates of 84% and 88%, respectively, their toxic effects were still highly significant when compared to the negative controls, which exhibited only 4% mortality ( F = 45.78; df = 6, 28; P < 0.001).

100-Seed weight (swg) showed highly significant variation among EMS treatments (P < 0.001).

The Moran’s I indices for elevation, slope, and vegetation coverage display highly significant positive spatial autocorrelation, reaching peak values ( P < 0.001) during the Yuan Dynasty.

There is a highly significant association between article type and journal category (χ 2 = 527.15, P < 0.001), with collaborative articles being predominantly published in nonplastic surgery journals (n = 1534; 77.4%), whereas noncollaborative articles were almost exclusively published in plastic surgery journals (n = 2803; 99.6%).

Among survivors aged 60 years or older, survival declined stepwise from robust to pre-frail to frail, with highly significant between-group differences (log-rank P < .001; Fig. 3 B).

Subgroup analyses were conducted for repeat PDT (Re-PDT) and secondary choroidal neovascularisation (CNV). Results Overall, PDT led to a significant improvement in visual acuity (p = 0.041) and a highly significant reduction in both CRT and SRF (each p < 0.001).

Intra-group analysis demonstrated highly significant reductions in CRP from baseline to Week 8 (Del-Immune V: p < 0.001; Control: p = 0.001).

Importantly, our multivariate analysis already adjusted for all major clinicopathological confounders (age, gender, smoking status, clinical stage, PD-L1), and the association between Ki-67 and MPR/pCR remained highly significant (adjusted OR per 1% increase = 1.069, P < 0.001), suggesting that the observed predictive value is robust against measured confounding.