“highly significant”

The effect of the fly strain on CCRT was highly significant (Kruskal–Wallis test, p < 2.2 × 10 −16 ).

There was a highly significant correlation (Spearman’s rho of 0.81, p < 2.2 × 10 −16 ) of the PBMC expression changes 6 h after HIIT and HBO 2 ( Figure 5 D).

In fact, the least significant (i.e., highest) p -value observed in any factorial ANOVA corresponded to a main effect term (intrinsic disorder in Plants: p = 4.13 × 10 −6 ), while all other terms across all analyses were highly significant ( p < 2.2 × 10 −16 ).

At the nucleotide level, the nonrandom distribution among these genomic categories is highly significant ( P < 2.2 × 10 − 16 in a χ 2 test for independence).

Despite major differences in experimental design, including the developmental stage of the worms, the overlap with the single-cell cis eQTLs was highly significant, with 335 cis eQTLs shared between the studies (OR = 7.2, p < 2.2×10 −16 , Fisher’s exact test) ( Figure 3C ).

Food Deserts: In stark contrast, the food desert index showed a strong and highly significant positive spatial autocorrelation (I = 0.4563, p < 2.2 × 10 −16 ).

A comparison of frequencies with Pearson's chi-squared analysis showed a highly significant increase of negative probes in the immune group ( p < 2.2e − 16).

The correlation coefficients were relatively low (0.325, 0.323, 0.321, 0.312 and 0.250 at the PARTE temperatures of 23, 30, 37, 55 and 75°C, respectively) but highly significant (all P -values < 2.2e-16).

The overlap between CNM genes and genes correlated with aging was highly significant (p < 2.2 × 10 –16 , Fisher’s exact test).

For all three species comparisons, a linear regression of %ID and log 2 hybridization ratio showed a strong and highly significant correlation ( D. sechellia : Multiple R 2 = 0.3257, P < 2.2e-16; D. simulans : Multiple R 2 = 0.2920, P < 2.2e-16; D. yakuba : Multiple R 2 = 0.4083, P < 2.2e-16) (Figure 2 ), with the data for D. yakuba showing the strongest correlation.

0.00276, Fisher's exact test p-value = 1.34e-05), there is a highly significant excess of sites supporting the species topology (0.00229 vs. 0.00210, Fisher's exact test p-value < 2.2e-16) and deficit of sites in these regions supporting ILS topologies (0.00042 vs. 0.00066, Fisher's exact test p-value < 2.2e-16, Fig 2B and 2C ), which suggests that the observed reduction of ILS is not the result of a lower mutation rate.

The investigation into the relationship between the effect sizes of ASVs and their respective taxonomic groups revealed highly significant results (Kruskal–Wallis test, P − value < 2.2 × 10 − 16 ) for both N conditions on all three days, suggesting a disproportionate enrichment of large effect ASVs within certain taxonomic groups.

These results show, that RNAs with diminished abundances in the mutant possess a particularly high amount of cleavage sites, which was also indicated as highly significant by hypergeometric test (enrichment over background distribution of cleavage sites: 6.23-fold; p-value <2.2 −16 ).

We observed a very weak but highly significant correlation in synonymous heterozygosity between species (Pearson’s r = 0.14, p<2.2e-16), consistent with some degree of conservation for genic parameters of mutation rates and/or selection at Drosophila synonymous sites [ 58 , 70 – 74 ].

We find a highly significant linear relationship between ψ and Fop ( F = 5325, P < 2.2 × 10 −16 ) as well as a strong positive correlation, measured as Spearman’s rank correlation coefficient (0.825).

For each month, the differences between soil and soil + root for COS and CO 2 were highly significant (Kruskal-Wallis rank sum test – p < 2.2e −16 ), with higher CO 2 and lower COS emissions in the soil + root chambers (except for February) (Fig. 3 ).

The model describing recovery rate ( rr ) was highly significant ( X 2 = 27,605,272, df = 23, P< 2.2e -16 ), with each term of the model being significant ( S2 Table ).

all clusters, and highly significant p-values for both directions (lesser and greater, p-value < 2.2e-16) are recorded.

Averaging power in this range across the entire cue presentation period revealed a highly significant difference between the six regions in the 3-s spatial working memory task (F 5,1096 = 19.98, p = 2.2E-16, effect size: η 2 = 0.09).

Remarkably, we observed a highly significant negative correlation between B cell levels and HEUScore among all immune cell subtypes ( r = -0.8857, P < 2.2e-16) ( Figure 5G ).

In both cases the difference in expression level was highly significant ( p < 2.2e-16) indicating that the coverage of those genes was too low for an assembly of at least 55% in one species.

These differences are highly significant (X 2 test p-value < 2.2e-16).

There was a highly significant effect of orchard on epiphyte species richness per tree ( F 4,607 = 358.17, p < 2.2 × 10 −16 ) and a highly significant effect of cultivar nested within orchard ( F 5,607 = 20.92, p < 2.2 × 10 −16 ; Appendix S2).

Wilcoxon rank sum test with continuity correction revealed highly significant changes for old versus young cortex and hippocampus circRNA TPM values ( P < 2.2 E-16) ( Fig. 2d ).

The analysis revealed a highly significant enrichment ( p < 2.2 × 10 −16 ) of QTLs within CNVRs.