“highly significant”

Finally, a highly significant upregulation of renal versican, i.e. 8.0 fold (p<0.001) increase over control, was observed in rats with Passive Heymann Nephritis (PHN) - a severe model of proteinuric nephropathy which partly resembles human membranous nephropathy (MN) - studied at 6 months.

Although this increase was small, it was highly significant ( P <0.001).

The ANOVA revealed a highly significant difference in 2 h HPF intake in the 4 groups of rats ( F (3, 26) = 19.32; P < 0.001).

Results Chemical Parameters Fresh litter material showed distinctly higher contents of total phenolics in dwarf shrubs than in herbaceous plants (F 1 , 22 = 57.10, p<0.001), differences between plant species were highly significant (F 7,16 = 61.55, p<0.001) ( Table 1 ).

PF Ang-2 levels were higher than serum Ang-2 levels in patients with pleural exudates and patients with transudates and that was highly significant ( P <0.001)( Table 3 ).

Moreover, even though all three experiments were carried out under the same greenhouse conditions, ANOVAs showed highly significant differences ( p < 0.001) between the replications.

Moreover, highly significant differences were found when comparing accumulation of each HM in snail hepatopancreas with that in foot (Cu, Zn, Cd, Pb: p < 0.001).

The log-rank test for equality of survival curves was highly significant at P = 0.001.

In girls the difference was highly significant (18.3% of the 11 yo, vs. 25.5% of the 15 yo; p<0.001 among age groups).

Conclusions Our study shows an important, highly significant accumulation of the heterogeneous genotype of the Sirt1 SNP A2191G (Ile → Val) when compared with healthy controls ( P <0.001).

Changes in these renal hemodynamic parameters were all highly significant after the addition of ramipril, and the decline in RVR was exaggerated compared with the response to aliskiren monotherapy (repeated-measures ANOVA, P < 0.001; Table 3 ).

The combination of P276-00 and gemcitabine showed highly significant apoptosis of 25.4% and 73% at 96 h and 120 h respectively as compared to either drug alone ( p < 0.001).

The differences are significant: likelihood ratio tests for models of b t , including a random effect to capture mouse to mouse variation, and accounting for temporal autocorrelation (fitted with lme in the nlme package in R) reveal a highly significant interaction between ‘day’ and ‘clone’ (likelihood ratio test: χ 2 = 2410, d.f. = 119, p < 0.001).

For a set of oocytes from a single frog, sustained inward current after washout of AM546 for K69C expressing oocytes averaged −129±13 nA (N = 9), which was a highly significant increase (p<.001, Paired T-test, final vs. initial holding current).

Therefore, we pooled mild and severe group together and compared with asymptomatic control, which came out to be highly significant [χ 2 1 = 35.8; OR = 3.566, 95% CI = 2.348–5.416 p<0.001] ( Table 4 ).

Brain size and tool use We find a highly significant correlation between body mass and brain size in Corvus (P < 0.001 Figure 3 ) both for the combined dataset and when analyzing the individual datasets from Mlikovsky [ 47 ] and Iwanuik & Nelson [ 48 ].

As for KRAS , such a heterogeneous distribution of PIK3CA mutations was found highly significant [p<0.001 (OR, 2.45; 95% CI, 2.36-2.55); p normalized scientific notation = 5.9 x 10 -4 ].

In particular, the differences between the negative control and the positive control, intravenous PGE2, and intraligamentous PGE2 groups were highly significant ( p < 0.001), while the difference between the negative control and the submucosal PGE2 groups was less pronounced ( p < 0.05).

Pain assessment in patients showed highly significant change from baseline VAS score to 4 th week of the therapy in gabapentin groups ( P <0.001) as compared to placebo.

When the whole group was divided according to a positive or negative Rigiscan a highly significant difference was found (p < 0.001) (Fig. 1 ) between age, degree of cavernosal fibrosis, and total and free testosterone levels.

Highly significant improvements (p<0.001) were found on each side when the second tests were compared with the original observations (Figures 4 and Figure 5 ).

In epicardial fat tissue we found a strong correlation between C16:0-CoA content and HOMA-IR ( r = 0.73, p < 0.001). Associations Between Bioactive Lipids and Cardiac Structure Alterations We found highly significant ( p < 0.001 in all cases) correlations between the content of some lipid species determined in adipose tissue samples and the left ventricular end-diastolic diameter (LVEDd) of the heart.

Results Range dynamics After removing the possible effects of geography, the difference in the current climatic niches of cinerea and coryphaeus was highly significant (PC1 climate : F 4, 53 = 24.77, P < 0.001; PC2 climate : F 4, 53 = 25.94, P < 0.001).

Seasonal SST trends There were highly significant interactive effects of time (half decade) and location on SST during all seasons (spring, n = 10,944, MS = 16.357, df = 21, F = 2.614, P < 0.001, Fig. 3 a; summer, n = 11,021, MS = 13.070, df = 21, F = 6.009, P < 0.001, Fig. 3 b; autumn, n = 10,745, MS = 27.592, df = 21, F = 3.054, P < 0.001, Fig. 3 c; and winter, n = 10,356, MS = 20.833, df = 21, F = 15.397, P < 0.001, Fig. 3 d).

As predicted, there was a highly significant interaction between Object valence and Scene component, [ F (1, 42) = 60.1 p < 0.001], which confirms the existence of the trade-off 24 h post-encoding (Figure 4 ).