“highly significant”

Night-time sleep disturbance There were highly significant reductions in night-time sleep disturbances (Fig. 4a ), with the median baseline VAS of 71 (21·75–78·5) being reduced to 10 (0–25·25) ( P = 0·001) by levocetirizine plus hydroxyzine and 17 (0–24·75) ( P = 0·002) by levocetirizine monotherapy.

In the RMS model, total RMS was not associated with BCVA (β ≈ 0.00 logMAR per μm, p = 0.997), whereas the time effect remained highly significant (β ≈ −0.97, p = 0.001).

In the CALLY analysis, the low-CALLY group had a markedly shorter median survival (20.1 months, 95% CI: 20.1–56.7) compared with the high-CALLY group (89.0 months, 95% CI: 89.0–111.3), with a highly significant difference (log-rank p < 0.001).

In fact at 5 min, the difference in mean TER (% of control value) between butaprost and AH6809 treated group (85% vs 116%) was highly significant (p<0.001).

The competence dimension, reflecting the students’ belief in their capabilities to perform effectively, was markedly higher among the trained group (18.77 ± 2.09) compared to the control group (15.82 ± 4.38), with a highly significant difference (t = 3.81, p < 0.001).

There was a difference between performance on the first 5 s of the SSB recordings and the last 5 s that was highly significant ( t = 8.186, p < 0.001).

There was a highly significant correlation between the extent of CAD and low HDL-C ( P < 0.001), [ Table 2 ], old age ( P = 0.003) and male sex ( P = 0.02) [ Table 3 ]. 21 (7.1%) patients were asymptomatic, 110 (37.3%) had stable angina, 127 (43.1%) had NSTE-ACS, 20 (6.8%) STEMI and 17 (5.7%) had HF.

In group B, out of 15 patients, 12 patients had attained normal skin color, which was statistically highly significant at the level of P < 0.001, also one patient had mild improvement and two patients have moderate improvement.

A highly significant difference was observed between the different age groups and the mean DMFT ( p < 0.001) ( Table 2 ).

This moderator had a strong and highly significant effect (F (1,160) = 11.19, p = 0.0010).

In terms of how well the PHQ-9, and GAD-7 total scores were associated with the two criterion instruments, the correlations were all highly significant (p <.001).

Dietary levels had highly significant (p<0.001) on percentage of DM, moisture, ash, protein and fat.

Results Overall, the FHSQ pain subscale exhibited the highest responsiveness, as evidenced by a highly significant paired t -test ( p <0.001), Cohen’s d = 0.63 (medium effect size), SRM = 0.50 (medium effect size) and Guyatt index = 1.70 (huge effect size).

There was also a highly significant association of high FAK expression with lymphovascular invasion (LVI) (p = 0.001) (Table 2 ).

Three results were highly significant (p-value<0.001) but there nevertheless is a risk of Type I errors.

With a large sample size (n = 500), the p-value for the difference between the experimental and control groups was highly significant (p < 0.001), suggesting that meditation reduced anxiety.

A preliminary experiment comparing the estimation of polyhedra in a series of dilutions by the above method and by haemocytometer count indicated a highly significant regression coefficient ( P < 0.001).

We make note of this result even though it exceeds our 0.005 cutoff because the main effect for Asian individuals compared to White individuals was highly significant (AOR = 0.10, p < 0.001).

Nonetheless, even with conservative adjustments, the findings would remain statistically significant as all main outcomes were highly significant ( P < .001).

Presence of step parents and substance use in the family was seen to be a risk factor for substance abuse and the association was highly significant ( P < 0.001).

abdominal pain, nausea, belching, bloating and flatulence, were all highly significant (Somer’s d (t) = 6.43 – 40.05, p <0.001), and interestingly the weakest correlation was found for abdominal pain (t = 6.43).

Within-subjects effects: The effect of life epoch was highly significant (F(3, 261) = 23886.217, P < 0.001).

The overall knowledge score improved in the high score group from 11.6 (1.4) to 12.0 (1.9) and in the low score group from 7.2 (1.0) to 9.9 (2.3), and the difference in learning outcome was highly significant (p<0.001).

The confidence level of study was proposed to be 95%; hence, p-value < 0.05 has been considered significant, p-value < 0.01 has been considered highly significant and p-value <0.001 has been considered very highly significant.

Clonidine at doses of 37.5 μ g/kg and 65 μ g/kg induced a highly significant [ F ANOVA (3, 20) = 90.46; P < 0.001] decrease in the mean hind limb withdrawal time (Fig. 2 ).