The latter metric was even highly significant (** p = 0.008) when calculated using an unpaired two-tailed t-test.
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The linear model was highly significant in all 18 regressions (maximum p -value = 0.008).
Additionally detected focal CNAs showed a highly significant enrichment for known cancer driver genes ( n = 38, P < 0.008).
Molecular assay As illustrated in Figure 6a , the colon cancer induced group showed highly significant increase (P=0.008) in level of TP53 gene expression as compared to control group.
The difference between NR/ACR30 and ACR50/ACR70 in pre-MTX samples was highly significant (1495ng/ml vs 2705ng/ml, p=0.008).
At 12 months, the GLP-1 cohort demonstrated a highly significant increase in the RD of 0.014 with a 95% CI of 0.004 to 0.024 in nonunion/malunion compared with the control group ( P = .008) ( Table 3 ).
No significant differences in the mean values of the KTW nor FGG shrinkage% across six time points ( p < 0.05) were observed, whereas highly significant differences in the mean values of GTT across six time points (F = 3.32; p = 0.008) were observed.
The log-likelihood ratio test results comparing the piecewise model to the simple linear model were highly significant ( p = 0.008).
The difference between the unaided and the aided condition was highly significant and clinically relevant in both groups ( p < 0.008).
The interaction between teamwork and job engagement is highly significant, b = 0.01, 95% CI (0.003, 0.02), t = 2.69, p = 0.008, indicating that the relationship between job engagement and job satisfaction is moderated by teamwork.
Compared to the null model (which included only the intercept term, assigning all patients the same baseline risk of 23.2%), the 24-week GPR model demonstrated highly significant reclassification improvement.: continuous NRI = 0.972 (95% CI: 0.000–1.160, P = 0.008), categorical NRI = 0.486 (95% CI: 0.259–0.711, P < 0.001), IDI = 0.024 (95% CI: 0.010–0.040, P = 0.002).
The positive correlations between resin collection and pathogen loads were highly significant for colonies with additional propolis (Kendall’s rank correlation: V. destructor : z = 2.43, r = 0.47, p = 0.008; DWV: z = 2.58, r = 0.5, p = 0.005), but weaker (Kendall’s rank correlation: V. destructor : z = 1.89, r = 0.37, p = 0.029) or not significant (Kendall’s rank correlation: DWV: z = 1, r = 0.20, p = 0.16) for propolis removed colonies ( Figure 3 a).
The decrease in NIHSS on day 5 compared to day 1 was highly significant in patients with ischemic stroke (mean change −0.447, P = 0.008) as compared to hemorrhagic stroke (mean change −0.370, P = 0.096).
In PC patients with a Gleason score of > 7, the inverse correlation was highly significant between baseline or radiation-induced NPB frequency with TL (r = −0.404; p = 0.008; r = −0.403; p = 0.008, respectively; Figure 3 E,F).
The p-values of coefficients for these three variables were highly significant (p ≤ 0.008), and thus we presume the regression model to be valid.
For heavier type 2 diabetics (BMI > 75 th percentile) there was a highly significant predictive power of the two genotypes for BMI (p = 0.008), with the presence of the T1431 allele being associated with an increased BMI (β = 2.9 kg/m 2 , p = 0.002) and the Ala12 allele showing a trend to reduced BMI (β = -1.7 kg/m 2 , p = 0.072).
Both the EFS and OS were highly significant across the three risk groups ( p = 0.008 and p = 0.004, respectively).
A correlational analysis between coach rated game intelligence and DF-total correct demonstrated a highly significant and moderate relation between the two factors ( r = 0.37, p = 0.008).
(Smoothed maps of the annualized, age-adjusted prostate cancer rates for all males in Virginia 1990–99 are shown in Figure 1 .) Statistical testing for global clustering was highly significant for the entire time period (Tango's Maximum Excess Events Test, p < 0.008) and for 1990–94 and 1995–99 separately (p < 0.001 for both).
The presence of aggregates at baseline was a highly significant predictor of the clinical response to anti-TNF treatment ( P = 0.008), demonstrating that RA patients with synovial lymphocyte aggregates may have a better response to Infliximab treatment than those with only diffuse leucocyte infiltration [ 59 ].
There are 3 highly significant SNPs ( p ‐value < 0.008) in both the arithmetic and percentage change models: rs2230433 within the Integrin Subunit Alpha L gene ( ITGAL ) [OMIM#153370], rs17844444 in Protocadherin Beta 6 gene ( PCDHB6 ) [OMIM#606332] and rs3733694 in Protocadherin Beta 7 gene ( PCDHB7 ) [OMIM#606333].
In the winter, these observed spatial distinctions were maintained and further expanded by an additional, highly significant divergence between the IPs and PLSs (F = 53.019, p = 0.008).
To eliminate possible discrimination due to outliers, a Spearman’s test was performed, confirming a highly significant correlation with β2M ( p = 0.008), plasma cell percentage ( p = 0.035), C-reactive protein ( p = 0.043), and serum calcium levels ( p = 0.038), as shown in Figure 3 A.
This highly significant difference in the measuring of the vaginal length (p = 0.008) was however not surprising: besides the ‘observer-bias’ there is also an important influence of the circumstances and environment.
Serum Claudin-1 (but not IL-17A) levels show a highly significant difference ( p = 0.008) between early-onset and late-onset psoriasis patients (Figures 1(b) and 1(e) and Supplementary Table 3 ).