The unadjusted HR was 2.248 with a 95% CI of 2.105 to 2.401, which was highly significant ( p -value < 0.0001).
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In each subject large off–axis placement of the laser beam caused a highly significant (p < 0.0001) RNFL thickness measurement artifacts in almost all sectors.
3.5 Impedance drop AI was found to have a highly significant but weak correlation with impedance drop that was similar in the protected group and the control group ( ρ = 0.16 – 0.25, p < 0.0001; Figure 4 ). 3.6 Lesion‐to‐lesion progression There was a closer spatial relationship between consecutive lesions (not necessarily adjacent lesions) in the protected group in the posterior part of the PV encircling lesion set but with no statistically significant difference (5.4 [IQR = 3.6 – 9] mm vs. 5.5 [IQR = 3.7 – 9.3] mm, p = 0.051).
However, final infestation levels showed highly significant differences among treatments ( p < 0.0001), with T1, T2, T3, and sublimated oxalic acid (T4) significantly reducing mite infestation compared with the control.
We conducted a sphere formation assay on agarose-coated plates, which minimized cell adherence to the surface, and observed a highly significant increase ( p < 0.0001) in the number of spheres formed in the groups; BDFO and BNFO, respectively, as compared to the control group, BNFN whereas FDBO and FNBO cells did not show any considerable change (Fig. 4 a, b ).
Results showed a highly significant positive correlation between average promoter CpG methylation and IFNG RT-qPCR ΔCt (Spearman R = 0.67, p < 0.0001, Figure 2C ), demonstrating increased IFNG promoter methylation is associated with decreased IFNG RNA expression.
The analysis revealed a highly significant difference in symptom severity distribution (χ2 = 18.13, p = 0.0001, and degrees of freedom = 2).
Mixing was a relatively sensitive method of detecting the most highly significant changes (p < 0.0001) (86% of changes detected), however it was not very specific; as many as one third of gene expression changes showing p < 0.05 in mixed samples were not confirmed by individual profiles.
The highest percentage of kidney pathology in PCR‐positive fish was detected in the 0+ fish age class (85%), this category shows a highly significant difference compared with age categories 1+, 2+ and 3+ ( p < 0.0001), whereas no significant differences were detected among the remaining groups (Table 1 ).
The Kaiser-Meyer-Olkin measure of sampling adequacy was .94, and the Bartlett’s test of sphericity was highly significant (chi-squared = 1399.29, df = 44, p < .0001).
All comparisons revealed highly significant differences (p < 0.0001), with GN and FZ consistently exhibiting stronger inhibition than THC.
There was a highly significant difference between level of income of countries and the rate of beginning implementation (LRS 27.2; 3 d.f.; P < 0.0001), this difference being almost entirely accounted for by the difference between high income countries and the others.
At 4 wpi, the mean plasma viral load was 4.0 × 10 6 copy eq./mL A multivariate analysis of variance (MANOVA) was performed for all metabolites across all time points and brain regions, and highly significant differences were found (P < 0.0001).
Eighty-seven per cent of markers in the CEPH data and 83 per cent of markers in the NASC data had greater heterozygosity than the corresponding marker in the Samoan data; a sign test showed that both of these differences were highly significant ( p < 0.0001 for both tests).
This difference in the survival rate was highly significant in comparison to both the control Vehicle treated group (p<0.0001) and the PLX-Mat group (p<0.005).
In both cases, the differences between the genotypes are highly significant (accelerated: P <0.0001; rocking: P <0.0001, two-way ANOVA).
The differences in Kiss1 mRNA levels between hpg and age-matched WT females and males were found to be highly significant by two-way ANOVA (P<0.0001, both female and male) from day 30 onward (P<0.05; Bonferroni post-hoc).
Although highly significant (chi-square test, p<0.0001), the rather low fraction may indicate competition between CLK:BMAL1 and NPAS2:BMAL1 for binding sites.
Despite Fisher’s exact test showing a highly significant result ( p -value < 0.0001), the low phi coefficient suggests that this significance was likely due to the gender imbalance in the schizophrenia group, particularly the lower number of female participants.
The doe parity effect was highly significant ( p < 0.0001) on TD and DMY, while it was non-significant ( p > 0.05) on UW, UD, UC, UDG, and UV.
This highly significant bootstrap P -value ( P < 0.0001) suggests that right-hemisphere dominance is a robust and consistent feature of the neural response to DAF.
The influence both of cellular age and of radiation dose onto the number of micronuclei was highly significant (ANOVA test p < 0.0001).
Results from the analysis of variance and the F-test indicate a highly significant F-value ( p < 0.0001), suggesting that both variables contribute meaningful information to the model.
As indicated in Supplementary table 7 , the regression model was highly significant ( P < 0.0001), while the lack-of-fit term was not significant ( P = 0.4145).
The median values of t 90 were the longest in smokers and the shortest in nonsmokers and this effect was highly significant (p <0.0001).