“highly significant”

In a multilevel model describing HbA1c as dependent variable, the predictor time was highly significant at all time points (p < 0.0001), using time as categorical variable (drop of HbA1c at: Visit 4 = -2.3308, Visit 3 = -2.3583, Visit 2 = -2.0816, Visit 1 = -1.2916) or as continuous variable (drop of HbA1c per time unit = -0.5964).

Wilcoxon signed rank testing revealed no significant difference between the A1 and O1 groups (P = 0.1810) but a highly significant difference between the A2 and O2 groups (P < 0.0001).

Approximately 33.3% of all MC17 isolates were resistant to 5FC and this was found to be highly significant ( p <0.0001, Chi-square; p = 0.0005, Fisher exact test) when compared to the presence of 3.9 and 9.5% of resistant isolates in MC8 and MC3, respectively.

A lower number of migrated cells can be observed in LIPUS-stimulated cells, and this difference was highly significant at 6 h ( p < 0.0001) (Fig. 4 C).

Comparison of CD3 staining within the spinal cord parenchyma, but not the meninges, across treatment groups revealed highly significant differences between all treatment groups and vehicle-treated controls (Table 3 One-way ANOVA parenchyma: F = 10.56, p < 0.0001).

aegypti genes are without introns compared to 33% of the EZGs, and this difference is highly significant (P<0.0001).

3.6 Relationship between SPT wheal size and sensitization There was a highly significant and strong positive correlation (r s = 0.90; p < 0.0001) between the average SPT wheal size of all pollen species and the number of pollen species with a positive SPT result.

In animals subjected to the streptozotocin protocol (STZ-DPN), there was a highly significant ( p < 0.0001) reduction (95%) in PWT (>0.12 g i.e., static mechanical allodynia) which was restored to a level that was comparable to the saline-treated group (>2.5 g) by the dose of gabapentin (75 mg/kg) as the positive control standard drug ( Figures 1A–C ).

Importantly, the interaction of Language Type and Order was very highly significant [ F (1, 38) = 60.56, p < 0.0001], because IF phrases abounded in OV, FI phrases in VO languages.

Differences between the two inhalers in PIF were highly significant in all five study groups (p ≤ 0.0001), while statistical significance (p < 0.05) was observed with maximum ∆P in the four patient groups.

Moreover, a drastic fall was observed in case of IgG4, where the difference became significant as early as on day 30 ( P = 0.0027) and was highly significant on day 365 ( P < 0.0001).

The absolute numbers of MAP determined by F57qPCR were approximately two log 10 greater than the CFU counts from culture at respective ODs (Figure 1 ) and a highly significant statistical difference ( P < 0.0001) between all the compared samples was observed.

hyodysenteriae WC antigen in the 20 pigs on the uninfected farm A did not show a significant change during the course of experiment, while there was a highly significant ( P < 0.0001) increase with time in the cohort on infected farm C (Figure 2 , panel A).

Figure 1 compares seropositivity rates between RA patients with and without shoulder pain, revealing a highly significant difference (p<0.0001).

When the association was analyzed using 500 kb genome windows, a highly significant and positive, but very weak, correlation was found; gene density explained only 3% of the variance in off-target site density ( Figure 2C ; r = 0.17, p < 0.0001). 3.2 Targeted sequencing depth To estimate the coverage depth obtained by the bait-capture targeted sequencing approach at off-target sites, we computed the depth of coverage at pre-filtered variant sites identified by Mutect2 ( Figure 3A ).

Spheroid ciliary beat frequency discriminated highly significant between healthy controls (9.3 Hz) and PCD patients (2.4 Hz) ( P < 0.0001).

When all species are considered there is a highly significant correlation between the mean number of binding sites per protein and biological complexity (r = 0.7000, P < 0.0001; Figure 4a ).

Immunophenotyping revealed marked increases in EVs derived from neutrophils (CD66 + , CD16 + ), T lymphocytes (CD3 + ), leukocytes (CD45 + ), platelets (CD41a + ), and endothelial cells (CD51/CD61 + ), all of which were highly significant ( p < 0.0001).

A highly significant trend emerges from the data (Cochran–Armitage Trend Test = −4.72, p < 0.0001): as the absolute value of the Tmax/Dmax ratio increases, the physiological outcome decreases, from 52.4% in the first quartile, 33.3% in the second quartile, 14.3% in the third quartile to 0.0% in the last quartile, respectively.

Similarly, NEAT1 and HOTAIR showed markedly higher expression levels in advanced-stage CRC, with highly significant differences between the two stage groups ( p < 0.0001 for both).

Indeed, a comparison between the times of peaks and troughs of conidiation showed large differences between these phase markers in a Δ frq strain, and a detailed statistical analysis (paired t -test) for peaks and troughs of conidiation confirmed that these differences are, with one exception, highly significant (paired t -test, P < 0.0001; see Table S2 for t - and P -values for all phase markers, T cycles, and strains analyzed).

Fisher's exact test indicated highly significant differences across all groups ( p < 0.0001), reinforcing the potential of epitope 5 as a reliable diagnostic marker.

In addition, when all cells were pooled and subsequently treated with puromycin, a strong and highly significant (2-tailed t-test, p< 0.0001) depletion of the barcode associated with the puromycin-less vector was detectable whereas all other barcodes remained unchanged ( Supplementary Fig. 6 ).

All groups, except angiosarcoma (p value = 0.386), retained a highly significant increase of serum DR6 compared to normal controls (p values<.0001–0.0044).

The Phase effect was highly significant [ F (3, 12) = 42.1, p < 0.0001] simply reflecting the fact that the different phase have different durations.