“highly significant”

Its frequency was significantly higher in Rufiji than in Kilombero-Ulanga between 2001 and 2002, yet the increase of this allele during 2001- 2002 period was highly significant in both Kilombero-Ulanga (p ≤ 0.0001) and Rufiji (p ≤ 0.0001).

Strong and highly significant positive correlations were observed between IVS volume and both gestational age (Pearson’s r = 0.891, p < 0.0001; Spearman’s ρ = 0.920, p < 0.0001) as well as estimated fetal weight (Pearson’s r = 0.860, p < 0.0001; Spearman’s ρ = 0.927, p < 0.0001).

Therefore, iodized salt intake appeared to be related to a highly significant reduction in the incidence of thyroid nodules ( P < 0.0001 in a chi-squared analysis).

There were highly significant differences among the weights (wet) of the three life stages (ANOVA, F = 15.299, df = 62, 2, P < 0.0001).

The overall effect was highly significant ( Z = 9.00, p < 0.0001), confirming that elevated IAP is consistently associated with adverse clinical outcomes.

Highly significant levels of IBD were found across all catchments (North and South Islands) ( p < 0.0001), and when tests were conducted among the South Island populations (excluding Rotorua and Wairarapa), the IBD values remained significant ( p = 0.002; Figure S2 ).

When the mammary tumor survival data of all homozygous MMTV-BRCA1 and MMTV-BRCA1sv transgenic lines were compared against nontransgenic controls, a highly significant effect on mortality was noted (Fig. 7 A, P<0.0001 for both lines versus nontransgenic controls).

Highly significant differences ( p < 0.0001) were observed between the negative control and the IBV TW-II-infected group, and between the IBV TW-II-infected group and the groups treated with 50 mg/ml LF ( Fig. 12 B).

The increase was highly significant ( p = 0.0001) with both htyr doses at 24 h, coinciding with a complete closure of the cell-free space ( Figure 2 B).

Consumption of 15 g alcohol or more per day was associated with a relative risk of 1.6 (95% CI, 1.3 to 2.0) and there was evidence of a highly significant increase in risk with increasing reported alcohol consumption (Mantel extension χ for linear trend = 4.2, P <0.0001).

Nonetheless, just 9.2% (95% confidence intervals 7.3–11.2) of control women met the criteria for metabolic syndrome, more than five-fold fewer than our endometrial cancer patients, a comparison that was highly significant ( p < .0001), and mirrors previous work ( Rosato et al., 2011 ).

Highly significant association was found between naive CD4 T cells and CD4+ RTE (all p-values <0.0001).

The average opposite/same ratio was 0.517 (0.123 SD) for the participants with normal vision, and 1.043 (0.06 SD) for the participants with stereodeficient vision, and their difference was highly significant ( P < 0.0001, two-tailed t -test), even with our relatively small population size.

The pairs of the two variables, showing a very highly significant positive correlation ( P ≤ 0.0001) in all animals, indicate that the data profiles conjointly increase and decrease.

Kras Low mice exhibited ∼26% recombination, Kras Mod mice ∼46%, and Kras High mice nearly complete recombination (∼98%) with all comparisons highly significant ( P < 0.0001).

This difference between CD8 and CD4 was highly significant comparing all time points (10 d to 7 m) (p = 0.0001, Anova).

S3 and S5 gave highly significant increase in solubility with p < 0.0001 with no significant difference between them ( p = 0.6891, > 0.05), which means this method was more efficient in the complex formation.

3 Results 3.1 Effects of climate, geographic site, land-use system, and their interactions on tree diversity Among the factors tested, land-use system had a highly significant effect ( P < 0.0001) on tree species richness, abundance, evenness, and Shannon diversity indices ( Table 3 ).

Ordinary one-way ANOVA showed highly significant differences among the four severity groups for all three proteins (all P < 0.0001).

The results indicated that drug release from all the screened formulations was very highly significant compared to that from drug suspension ( P < 0.0001), thus suggesting a higher bioavailability potential of the drug.

One-way ANOVA revealed a highly significant difference between groups [ F (5,16) = 86.47, P < .0001, R 2 = 0.96], with significant variance heterogeneity detected by Brown-Forsythe ( P < .0001).

Statistical Analysis: Paired t -test analysis was used intragroup whereas unpaired t -test was used intergroup between experimental and control groups with significance at P = 0.05 and highly significant at P = 0.0001.

Repeated-measures ANOVA for condition type (reappraisal, suppression, view, and neutral) revealed a highly significant effect of condition [ F (3,72) = 104.16, P < 0.0001].

Beginning at doses >50 mg/kg, CSE reduced TGF-β levels toward those of the control group, while simultaneously restoring E-cadherin expression, with highly significant increases at 100 and 150 mg/kg ( p < 0.0001).

Temperature (T) and aging time (D) showed highly significant effects ( p < 0.0001), while humidity (H) also demonstrated a significant influence, with all three main factors falling below the 0.05 threshold.