“highly significant”

Highly significant differences were observed for PCA in PC1 (p < 0.0001) and for PCoA (p < 0.0001).

The least square (LS) mean differences compared with placebo in SPID6 values for the 62.5, 125, 250-mg, and combined DFN-15 groups were −756.6, −1120.7, −1355.1, and −1076.9, respectively, which were statistically highly significant for all comparisons ( P < 0.0001, ANCOVA model).

The effect of the factor ‘year’ was highly significant ( P < 0.0001).

For the primary variable GIS the difference between placebo and verum after 28 days of treatment showed a highly significant (p < 0.0001) difference between placebo and verum (6.7 resp. 4.7 points).

Consistent with our previous reports, while Pter treatment alone led to decreased angiogenesis in tissues (CD31 staining), combination treatment showed highly significant ( p < 0.0001) reduction in vessel formation and secretion of VEGF‐c and IL‐1 β levels in serum compared to all other groups.

Looking at the association between BCR reactivity of DLBCL cells and the presence of hypophosphorylated Ars2 isoform overall, considering data from both cell lines and cases with cryospecimenderived recombinant Fab, the association was statistically highly significant (Fisher exact t -test: two-tailed P <0.0001).

The heterogeneity in the studies was highly significant with I 2 value of 78.36% and the corresponding p-value < 0.0001.

However, it should not pass without notice that many of the incremental reductions in Table 4 are highly significant ( p < .0001) up to about n -5.

In replicated hydroponic experiments showing highly significant differences in seminal root length ( P < 0.0001) between 1RS and 1RW, we analyzed the aerial part of the plants.

The Analysis of Variance on memory performance on the three word categories across the two participant groups revealed a highly significant main effect of word category in both ISR ( F (2, 40) = 33.9, p < 0.0001) and DSR ( F (2, 34) = 48.4, p < 0.0001).

Results Plasma 5‐hydroxyindoleacetic acid (5‐HIAA), the major metabolite of serotonin (5‐HT), was significantly higher in delirious and non‐delirious cognitively impaired subjects as compared to control individuals without delirium and cognitive impairment ( p < 0.001 and p = 0.007), which remained highly significant after excluding patients taking psychotropic medication ( p < 0.0001 and p = 0.003).

MUAC was the variable with the highest area under the receiver operating characteristic (ROC) curve, 0.76 (95% CI 0.70 to 0.83), and was highly significant (p<0.0001).

The analysis of variance for stem rust reaction showed highly significant differences ( P < 0.0001) among accessions included in the whole collection, the durum sub-sample and Q2 group.

The antibody increase was highly significant ( p < 0.0001), with a 28-fold GMC increase (95% CI: 17–43-fold) ( Figure 2 B).

19 The effect of albumin concentration on clearance was small (~ 3% increase over the range of albumin concentrations—17–53 g/L—in the dataset) but was highly significant ( P < 0.0001) and was thus kept in the model.

Incubating the cells for 24 h with LDC-3 displayed a significant decrease in the PTPIP51/PTP1B complex formation for 0.5 μM and 5 μM LDC-3 (0.5 μM: p < 0.05; 5 μM: p < 0.001) and a highly significant increase of interactions at concentrations from 25 μM to 60 μM being at 25 μM ( p < 0.0001), at 50 μM ( p < 0.001) and at 60 μM ( p < 0.0001) ( Figure 6 ).

The differences between the 3 strata for all-cause mortality was highly significant for all participants ( P < .0001) and when restricted to participants with CD4 ≤100 cells/mm 3 ( P < .0001).

The LOD scores obtained for the QTL in both families were highly significant ( p < 0.0001).

As shown in Figure 1 a,b, there was a highly significant correlation between results from the sVNT and the live-virus NTs for both variants (Spearman’s r = 0.92 and r = 0.80 for WT and Omicron, respectively, both p < 0.0001).

A highly significant correlation was observed between nuclear matrix protein level and 8-OHdG, highest in SA for BLCA-4 ( R = 0.583, p = 0.0001) ( Table 6 ).

Notably, the region was highly significant ( p < 0.0001), with substantial variation observed across different geographic areas.

From a technical point of view, we achieved a highly significant intra‐ (Spearmans ρ = 0.8729, P < 0.0001***) or interobserver (Spearmans ρ = 0.8577, P < 0.0001***) agreement of manual GAM quantification.

The primary endpoint was archived by 53% of the patients in the rhPTH(1-84) group compared with only 2% in the placebo group, which was a highly significant difference ( P <0.0001).

A highly significant variation ( p < 0.0001 ) was observed for the genotype, environment, and G × E interaction in all the studied traits.

ANOVA results indicated a highly significant model, as demonstrated by an exceptionally high F-value of 644.09 and a low probability value (p-value < 0.0001), underscoring the reliability of the developed model (Table 5 ).