“highly significant”

A highly significant difference (p < 0.0006) was observed when we plotted and compared the fold regulation of STAT1-dependent genes vs .

A comparison of the mEHT-treated and nontreated patients with the same stage brain tumors in the same research group in Italy [ 74 ] showed a highly significant ( p = 0.0006) response rate compared to the conventional control and also for GBM ( p = 0.026).

More formally, using a mixed linear effects logistic regression model that treated dataset as a random factor (which also controlled for SNP platform because dataset was nested within each platform), the overall association between schizophrenia and Froh in the combined sample was highly significant (β = 16.1, z = 3.44, p = 0.0006 in the imputed data, and β = 17.98, z = 3.89, p = 0.0001 in the raw data).

This showed that pollen expression levels of the CCP proteins was very highly significant ( p = 0.0006).

The difference was highly significant for total species richness ( χ 2 = 11.921, P = 0.0006) and exclusive species richness ( χ 2 = 42.667, P = 0.0001) but was not significantly different for the richness of plant families ( χ 2 = 1.463, P = 0.2265, Figure 3 ).

The first primary outcome variable tested, the difference between groups in TBUT, was in fact, highly significant (p=0.0006), and it is worth noting that the difference between groups for the second primary outcome, OSDI, did not approach statistical significance (p=0.9843).

However, in the peritoneal cavity, a major anatomic residence of B-1 cells, neonatal SpA treatment resulted in a highly significant mean 78% reduction ( P = 0.0006) in the frequency of V H T15 transgene–expressing peritoneal B-1 cells (Mac-1 + B220 + ) (7.9 ± 1.1%, n = 7) compared with control treated mice (36.5 ± 3.2%, n = 6) ( Fig. 7 A).

Although Cox proportional hazards regression does not provide a simple statistic (like R-square) to measure the percentage of the total variance in switching explained by the model, the relative "fit" of the model, as assessed by comparing the model with versus without the six predictor variables, indicated a highly significant fit (likelihood ratio = 23.836, p = .0006).

The effect of combination therapy was highly significant with regard to resistance suppression, as shown in Fig. 3 ( P = 0.0006; Breslow-Gehan test).

The difference in survival between the vehicle-treated control group and the NEO212-treated group was highly significant ( p = 0.0006).

This difference in curvature is somewhat subtle, but was very highly significant ( p = 0.0006, permutation test).

While no such association was observed for older males, a highly significant sex-specific effect was observed when comparing female with male G -allele carriers ( P = 0.0006).

Additionally, these correlation coefficients are highly significant, having p -values < 6 × 10 − 4 .

A t-test comparing RISKDIFF high revealed a highly significant difference between the two genotypes (5.0±1.3% for L/L versus −5.0±2.2% for S/L; t = 7.69, df = 5, p = 0.0006; Figure 3B ).

The differences in FLA value between alleles OsFLA6 AA and OsFLA6 GG were highly significant (Welch's t -test; P = 6.06E−04) ( Figure 3E ).

First, in our NSG study the difference between MmuPV1+DMBA and mock+DMBA groups was highly significant ( P = 0.00061), and no NSG mice treated with DMBA alone developed HSIL or cancer by the study endpoint.

As shown in Table 6 , for CVMI, the p-values were highly significant in females ( p = 0.00061) and males ( p = 0.00371).

The difference between experimental conditions was highly significant (W = 88, p = 0.00061).

In addition, when Subtype 2 was compared with all other subtypes combined, a highly significant survival difference is still observed (log-rank test, P = 0.00061).

Considering the polymorphic variants of SCN5A, rs1805124 (H558G), the G558 allele had similar frequencies in all studies (24.4%, 18.4% and 23.4%, respectively), with a highly significant association with the PR interval value ( p = 6.2 × 10 4 , heterogeneity of p = 0.09).

Plasma leptin levels follow the same pattern as body fat percent (AB interaction F 1,56 = 11.32, p = 1.39 × 10 -3 ), and fasting C-peptide levels also show a highly significant AB interaction term (AB interaction F 1,56 = 13.13, p = 6.29 × 10 -4 ) and a similar profile of dysregulation.

Even in the more challenging GSE59455 cohort, ICDRS still provided significant risk stratification ( P = 0.0089), and in GSE65904 the survival difference between high- and low-risk patients remained highly significant ( P = 0.00064).

The statistical comparability of the two clones revealed highly significant variations at all time points (day 1: p = 0.00064; day 2: p = 1.87E-06; day 3: 2.82E-17; day 6: 6.23E-06; n = 12) ( Fig. 1C ).

Additionally, Body Mass Index (BMI) categories demonstrated a highly significant association with readmission status (x 2 = 21.513, p = 6.4778 × 10 −4 ), characterized by a non-linear relationship where underweight patients exhibited the highest readmission rate (15.79%) and obese patients the lowest (11.49%). 4.2.

Using this approach, we found that a highly significant overrepresented upregulated pathway (p = 6.50E-04) was the Hsf1 ( heat shock factor 1 )-dependent transactivation pathway, with the following twenty upregulated transcripts supporting this pathway enrichment, including: Akt1s1 , Rptor , Tnfrsf21 , Serpinh1 , Hspa1b , Hspa1a , Col4a6 , Fkbp4 , Cryab , Mtor , Camk2b , Hsf1 , Ubb , Mlst8 , Hspb8 , Hspb1 , Hspb2 , Slc29a1 , Hspa2 , Dedd2 .