SPSS 27.0 independent-samples t tests revealed highly significant regional differences in fat, protein, and total-solid contents ( p < 0.001), whereas lactose levels were statistically equivalent; full results are presented in Table 1 .
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p < 0.05 was considered significant; p < 0.01 was highly significant; p < 0.001 was very highly significant. 3.
Notably, highly significant associations (FDR adjusted p < 0.001) were observed between S. undulatus and the dominant flea species, C. tesquorum and F. elatoides , with edge widths reflecting the high flea counts (620 and 560 individuals, respectively).
In contrast, Tg4510 mice treated with ACI‐16664 showed a highly significant ( p < 0.001) 51% reduction in aggregated hTau levels compared to vehicle‐treated controls.
Significant reductions were observed in the RFB group ( p < 0.05) and the MT group ( p < 0.01), while the CT group showed a highly significant decrease ( p < 0.001).
With respect to potential biological prognostic factors, highly significant correlations of moderate magnitude were observed between sβ 2 m and serum soluble CD30, serum interleukin-10 and serum ferritin ( p < 0.001 but Spearman’s rho 0.333–0.455), as summarized in Table 2 .
In this group, repeated measures ANOVA revealed a highly significant and robust main effect of time on the outcome measure (F (3, 15) = 198.98, p < 0.001), with a very large effect size (partial η 2 = 0.975).
The multivariate analysis of variance (MANOVA, Tables 4 and 5 ) revealed that the type of biodigestate used as feedstock for biochar production had a highly significant effect (partial η 2 = 0.52, 95% CI [0.41–1.00], p < 0.001) on all evaluated physiological variables in forage: fresh weight (MANOVA, F = 214.2, p < 0.001), dry weight (MANOVA, F = 140.0, p < 0.001), chlorophyll content (MANOVA, F = 376.4, p < 0.001), and moisture (MANOVA, F = 376.4, p < 0.001).
This was evidenced by their Childhood Autism Rating Scale (CARS), Social Responsiveness Scale (SRS), and Short Sensory Profile (SSP) scores (27.47 ± 7.95, 71.59 ± 11.55, and 156.47 ± 20.17, respectively), with a highly significant reduction in sensory hypersensitivity ( p = 0.001) compared to the WLT group, which presented more severe scores on CARS (35.89 ± 8.96), SRS (81.72 ± 7.68), and SSP (133.67 ± 11.65).
However, social norms were highly significant (p < 0.001).
Results: People with diabetes showed statistically highly significant less loss of axonal super‐excitability in both sensory and motor axons (SupEx isc motor −10.7 % vs. 1.3%, SupEx isch sensory −3.5 % vs. 13.9 %; p < 0.001).
The intercept showed a highly significant effect (F = 1092.113, Wilks' Λ = 0.012, p < 0.001), indicating a strong overall change in the dependent variables (PI and GI).
TNF-α levels showed a highly significant increase in the model group compared to the normal control group ( ### P < 0.001, Fig. 2 H).
All regression analyses were highly significant ( p ≤ 001).
Lower quartiles of GIPD demonstrated a highly significant association with increasing CMRs ( p < 0.001), as shown in Table 4 and Supplementary Figure 2 .
The Bartlett test of sphericity was highly significant (p < 0.001), which confirmed the prerequisite for factor analysis.
From the first session onward, significant differences began to emerge ( P = 0.016 for air blast; P = 0.038 for tactile), becoming highly significant in subsequent sessions ( P < 0.001).
This remarkable increase was quantitatively confirmed by a highly significant rise ( p < 0.001) in the fluorescence intensity of 2,7-DCFH-DA, a ROS-sensitive fluorescent probe.
In addition, the type of closure showed a highly significant difference ( P = 0.001), as extra-peritoneal closure was predominantly used in rectal tumors (78.8%).
The results showed that tobacco leaves from different regions in China exhibited highly significant differences in chemical composition (p-value ≤ 0.001), which may be attributed to the unique geographical locations and climatic conditions of each production area.
The three remaining predictors were highly significant (p < 0.001 for each parameter) and had regression coefficients comparable to those in the main model (surgical complications: 1.574 vs. 1.694; immediate urine production: −2.049 vs. −2.408; rate of change in serum creatinine: 0.233 vs. 0.233).
For breast cancer, the optimal ARIMAX model (0,0,1) identified a positive and highly significant association with PC1 at a lag of 18 years (β = 0.108, p < 0.001).
Respondents reporting xerostomia had substantially higher OHIP-G14 total scores (mean 26.7) than those without xerostomia (mean 17.3), and this difference was highly significant ( p < 0.001).
Age was a highly significant non-linear coefficient for GEDV with large inter-individual variance (p < 0.001).
Results The one-dimensional genome scan for NBA and TNB revealed the existence of two genome-wide highly significant QTL located on SSC13 ( P < 0.001) and SSC17 ( P < 0.01) with effects on both traits.