SAFE implements a rank-based global statistics that enables a better use of marginally significant genes than those based on a p -value cutoff.
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“marginally significant”
Sighted at
p>=0.1
In the literature
The EBCTCG meta-analyses showed also a marginally significant 20% decrease in CBC risk after adjuvant chemotherapy [ 17 ].
Though the response rate of 72.9% is higher than reported in most other studies, the dropouts might not be an unbiased category, and caution should be exercised in evaluating marginally significant findings.
In addition, there was a marginally significant effect of removal to increase graminoid production, because graminoid production was significantly greater under MBL removal than in controls.
Focusing on the models for the estrogen-positive and estrogen-negative subsamples the essential finding for the Uppsala cohort is that proliferation and stromal-decorin are independently prognostic for estrogen-positive tumors, but not for estrogen-negative ones, whereas stromal-laminin is either significant or marginally significant for the estrogen-negative subpopulation.
Covariates in the final models included age, level of education, household income, occupational activity status, and smoking which were significant or marginally significant in the univariate analyses.
The presence of a past BCG vaccination scar was associated with a higher seropositivity, but the association was weak and marginally significant when adjusted for covariates.
If the 2007–2008 A1C data were available and used in our analyses, we might have enhanced our analytic power and strengthened other associations of poor glycemic control with access to health care from marginally significant to significant.
An intervention might be found to have a marginally significant effect in an RCT with an under-representation of lower SES subjects, where trial participants have an overall lower burden of disease.
Allium vegetable intake was found to be associated with a marginally significant reduction in endometrial cancer risk among thinner women (OR=0.70, 95% CI=0.47–1.06, for the highest quartile).
We have no explanation for our finding of a marginally significant, 23% increase breast cancer, based on a total of 139 observed cases.
We analysed distance data from the most recent move and the total distance moved for up to five years since arrival, both giving the same picture, that is a marginally significant results with greater distances being associated with greater psychiatric disorders.
The combined group of likely mutation carriers (probabilities of 0.67, 0.50 and 0.25) had a marginally significant, modest 60% increase in the risk for breast cancer, but no increase in risk with higher likelihood of being a mutation carrier ( Table 1 ).
The samples have been split into two sets in order to save DNA and reduce genotyping costs: the first set ( n =2271 cases and 2280 controls) is genotyped for all SNPs and the second set ( n =2203 cases and 2280 controls) is then tested for those SNPs that show marginally significant associations in set 1 ( P -heterogeneity or P -trend <0.1).
The effect of modality on mean IRI was marginally significant with slightly larger intervals produced in the auditory condition (mean 325 ms, S.E. 0.69) compared to the visual condition (mean 303 ms, S.E. 5.50; F (1,12) = 3.56, p = 0.08, η 2 = 0.23).
Using outcome data for all participants, a marginally significant trend was found such that in samples with higher rates of lifetime drug (non-alcohol) abuse, individuals with the Met allele were at higher risk of violence ( β = 0.02, p = 0.09).
Marginally significant protective effects were shown regarding the consumption of vegetables (HR 0.93; 95 % CI 0.85–1.01).
Results At sampling level, only a marginally significant effect of daily relative humidity and temperature on the abundance of questing nymphs was identified.
Activation of the right MTG was also marginally significant (9 contiguous voxels).
Furthermore, breast feeding and mother's intake of alcohol during pregnancy was found to be marginally significant risk factors for AD in the child [15] .
The increase of Raven IQ in the videogame group was marginally significant, as was the decrease in Raven IQ in the documentary group.
Lampl et al .[ 19 ] in their randomized, placebo-controlled, double-blind trial to study the protective effect of magnesium sulfate infusion reported at the end of 1-month follow-up that the Barthel index was nonsignificantly higher while the Rankin disability score was lower (marginally significant) in the magnesium group.
There was a marginally significant difference in ACL injury and age.
A P value of less than 0.05 was considered statistically significant and a value of 0.05 ≤ P < 0.1 was considered as marginally significant.
Conversely, in a Finnish population of smokers, higher baseline blood α -tocopherol has been associated with a marginally significant increase in the risk of cardial GC ( Nouraie et al , 2005 ).