“may be significant”

Discussion Psoriasis is a chronic inflammatory skin disease that affects 1–3% of the population.[ 8 9 ] For most of the patients, the disease is more emotionally than physically disabling, as its impact on quality of life may be significant even if relatively limited BSA is involved, while for others it can be associated with an essentially disabling arthritis limiting daily activities to a considerable extent.[ 10 ] The prevalence of PsA varies worldwide, ranging from 6.25 to 48% in Europe, North America, and South Africa; but a prev

Secondly, there may be significant heterogeneity observed across studies.

However, and as it will be shown later in the present work, the errors in the description of noncovalent interactions may be significant, depending on the relative orientation of the interacting molecules.

pombe may be significant in this connection (Additional file 1 : Figure S1C).

The components of the HRQOL may represent independent predictors of survival and may be beneficial when used clinically to make treatment decisions.[ 7 ] Several studies in the literature on PBT have focused on the role of specific facets that may serve as significant prognostic factors of survival such as gender, cognitive and social functioning, depression, tumor location, and histological classification.[ 16 19 33 36 ] We have designed a study to attempt to determine which items of the EORTC QOL measures may be significant predictors of tumor progression on magnetic resonance imaging (MRI).

These investigations also suggest, although they do not prove, that there may be significant variability in annual LSM in children with cholestatic liver disease which may have implications for its use clinically and as an outcome measure for clinical trials.

49 Even among breast pathology specialists, disagreement in the categorization of ADH and DCIS may be significant. 49 Early pathologic classification of DCIS described its architecture. 50 The architectural types can be categorized as comedo, solid, cribriform, papillary, and micropapillary; however, many DCIS histopathologic specimens contain a mixture of architectures and is not believed to be prognostically discriminatory.

The atmospheric contribution of microplastics to Lakes Mead and Mohave is unclear but may be significant, particularly as the area is downwind of Las Vegas and other large metropolitan areas in California.

The epigenetics and epigenomics may be significant for crop adaptability and pliability to ambient alterations, directing to the creation of stout climate-resilient elegant crop cultivars.

The CRISPR/Cas9 anti-HSV-1 dose and therapeutic regimen, as well as those of acyclovir, may be significant variables for different models.

Along with other variables that may be significant predictors of child death, the ones identified in this study can formulate guidance on areas that require stringent monitoring to ensure that Sierra Leone reaches the sustainable development goals.

As could be observed during the COVID-19 pandemic, in these times, the psychological burden on the whole population and especially on children and adolescents may be significant. iCBT interventions could be crucial to meet the associated higher need for psychological interventions, providing comparable effects on internalizing symptoms to face-to-face CBT interventions. 5.

[ 42 , 43 ] In patients with acute liver failure (ALF), prolonged PT/INR defines the syndrome (along with hepatic encephalopathy) and may be significant, but does not predict bleeding complications although it is a marker of poor prognosis.

Also, light microscopy studies have suggested that there may be significant rearrangement of synaptic locations after noise exposure ( Liberman et al., 2015 ).

John population may be significant over time and may have acted as a steady infusion of new alleles to the population, even if the deer population of St.

This current result may be significant because the synchrony of decreasing precipitation and rising temperature may lead to high potential evapotranspiration and low water availability, not only in the Northern Chinese steppe ecosystem ( Wang and Gao, 2003 ; Cheng et al. , 2006 ) but also in many of the semi-arid regions of the world, such as the Patagonian region of Argentina ( Paruelo and Sala, 1995 ), the western European grassland ( De Boeck et al. , 2007 ), and the Chihuahuan Desert of the USA ( Patrick et al. , 2007 ).

Although our study effect sizes may be small, they may be significant on a population level and can inform clinical practice and public health guidelines.

In particular, there may be significant differences in the concept and practice of home-based end-of-life care in different cultural contexts.

7 , 8 Although targeting developmental abilities rather than co-occurring problems, RCTs in autistic populations have highlighted the importance of conducting longer-term follow-ups because intervention effects that are nonsignificant at end of trial may be significant later on. 9 This could be because intervention effects may take longer for benefits in child presentations to appear.

16 Removal of glucose during a dialysis session may be significant enough to require a different dose of basal insulin on dialysis and non-dialysis days. 17 Dialysis therapy also corrects hyperkalemia and acidosis associated with hyperglycemia.

However, in other cases, high permeance and limited selectivity are still observed, likely because the pore size of the COF is still significantly larger than the hydrated diameter of target ions and grain boundary transport may be significant.

However, for communication-bound tasks, the demonstrated improvement of the cartesian mapping may be significant.

The losses are caused by the attenuation of the guided wave due to material properties and due to the radiation of a leaky wave into the surrounding medium, which in the case of surrounding liquids or a soil may be significant.

Alternative sources within the Eurasian continent might also be considered; bitumen trade between the Black Sea and the Mediterranean is archaeologically attested in earlier periods [ 50 ] and although the source of this material is not proven its location on the inland river routes linking to the Baltic and North Seas may be significant.

A number of studies have previously estimated the time to perform remote and in-person device checks, yielding a wide range of time estimates, suggesting that there may be significant clinic-to-clinic variability [ 14 , 31 - 33 ].