“may be significant”

Hence, it can be assumed that its role in the pathogenesis of vascular diseases in the course of OSA may be significant.

Studies indicated that specific activators of PPAR α may be significant for the improvement of brain cell metabolism and cognitive function in neurodegenerative and neurodevelopmental disorders [ 57 ].

The application of prealbumin and RBP4 for frequent monitoring of endoscopic activity may be significant for the treat-to-target approaches and benefit CD patients.

Although there may be significant changes in the species composition of soil microbial communities in response to environmental changes, the functional genes within these communities remain relatively stable.

Even if the difference between the velocity may be significant for mixtures containing components with large differences in the molecular weight (in our systems carbon dioxide (MW 44) and hydrogen (MW 2)), it is likely that the errors are of the same order of magnitude of the uncertainties in the evaluation of the dispersion coefficients.

Notably, this study revealed that although MFCs might appear macroscopically similar and may obtain an identical macroscopic grading, the histological difference between such changes may be significant, ranging from the presence of occasional pigmented cells dispersed between seemingly unaffected myocytes to severe granulomatous inflammatory changes with abundant presence of melanised cells.

Potentially there may be significant differences in occupational hygiene measures in different settings that may have affected the extent of exposures and rates of respiratory symptoms in different studies (as was reported by Nayebzadeh). 34 Another weakness of this review involves the heterogeneity of the studies included in the meta‐analyses.

Given the reduced mobility and thus daily physical activity, eating behavior changes, as well as possible excessive or deficient food consumption caused by psychological stress, it may be suspected that there may be significant changes in body weight in the society during government restrictions caused by the pandemic.

Formal studies in cardiac surgery are sparse; however, cryoablation has been shown to be effective in pain control for patients undergoing open thoracic abdominal aneurysm repair.[ 66 ] In patients undergoing cardiac surgery via the minimally invasive or minithoracotomy approach, the pain may be significant even though the incision is smaller than a traditional sternotomy.

This recommendation is consistent with the need for flexible and adaptable approaches to immunization in fragile and conflict-affected settings, where logistical constraints and community trust issues may be significant barriers ( 18 ).

Furthermore, inhibiting HER may be significant in the therapeutic management of patients with BCBM, even in case of low HER2 gene expression [ 23 ].

However, in bone, collagen cross-linking is followed by mineralization, which leads to bone formation; therefore, the effect of factors other than collagen on bone density may be significant ( 11 ).

The further identification of gastrin and somatostatin receptors on the surface of the ECL cells has suggested that other neurohormonal influences may be significant in the regulation of parietal cell function, utilizing the ECL cell as an intermediate modifier.

It is feasible that differences between the groups may be significant if the time periods (e.g., eight hours for evening and eight hours for nighttime) were equal.

Thus we inferred that the level of antiTPO or antiTg may be significant to the development of RIHT and should be included in the nomogram.

This suggests that prolonged nicotine and alcohol exposure may be significant risk factors contributing to poor prognosis in AP patients.

Although further research on the complications and long-term results is needed, the benefits of using the endoscopic supraorbital keyhole approach for sellar ACs may be significant, and considering the complications associated with endoscopic transnasal surgery and further accumulation of cases is desirable.

However, especially in the moderate range of misophonic reactions, this discrimination may be significant.

This study specifically investigated the impact of varying drying temperatures on SDF and IDF balance, which may be significant for developing functional ingredients.

However, a number of sites discovered to be enriched for K-RTA were in distal promoter region, and may be significant for regulation of downstream target genes.

Conclusions and relevance The study findings suggest that decreased serum TGF-β and tubular atrophy with TGF-β immunoreactivity may be significant in cats with CKD.

The analysis consistently incorporates interfacial tension gradients (Marangoni stresses) as well as hydrodynamic slip at the oil–water interface, which may be significant for hydrophobic drops in aqueous environments.

Measurements of IgG-GS9 from two preparations showed only a slight difference in R H (0.1 nm), indicating that these measurements were quite robust and relatively small differences in R H may be significant.

As noted by Herms et al., a high discontinuation rate should not be perceived as negative per se as reasons such as satisfactory efficacy or treatment holidays may be significant and cannot be overlooked [ 25 ].

A number of studies have previously estimated the time to perform remote and in-person device checks, yielding a wide range of time estimates, suggesting that there may be significant clinic-to-clinic variability [ 14 , 31 - 33 ].