“modestly significant”

Interestingly, we observed that, in patients with late-stage HCC, the E2F7 gene showed significant differential expression between class I and class II cell populations, while a modestly significant difference of expression was found in stage II patients.

Correlation between chroAge and PhenoAge was strong for TW (r=0.93) but only modestly significant for TM (r=0.57).

The convergence of evidence from extensive pharmacovigilance signal detection across multiple international databases and the supportive, albeit modestly significant, causal inference from MR analysis provides a compelling argument for an association between rhGH and brain neoplasm.

Correlations of the change in body weight during GLP-1RA treatment We found a modestly significant correlation of weight loss (percentage) of pre-MBS weight to post-MBS nadir weight and weight loss (percentage) after 12 months of GLP-1RA treatment with semaglutide and liraglutide ( r = 0.206, p = 0.035; Figure 4A ).

Although the association is modestly significant, the direction and magnitude are consistent with studies from other LMICs where expanded immunization programs have contributed to reduced mortality [ 30 , 31 ].

He found that these learning effects are modestly significant and flow fairly easily internationally.

A previous investigation has shown modestly significant positive correlations between individual coronary function variables and MPRI ( 26 ).

However, the moderating or buffering role of eviction/foreclosure bans (indicated by the estimate for Expense Difficulty × Eviction/Foreclosure Ban on) is either insignificant (for depression) or only modestly significant (for anxiety) for these homeowner households.

Similarly, in fully adjusted Model 3, the association remained modestly significant, the OR was 1.06 (95% CI 1.01–1.11) regardless of age, sex, smoking, systolic BP (SBP), total cholesterol (TC), TG, FPG or DM2, BMI or WHR, education and alcohol intake ( Table 2 ).

In a large population-based cohort study of postmenopausal women with a history of oral bisphosphonate exposure, the use of Dmab was associated with a modestly significant 13% decreased risk of subsequent breast cancer, suggesting a potential protective effect of Dmab use on breast cancer risk in older women previously treated with bisphosphonates [ 34 ].

Nevertheless, for genes controlled in trans by HS6 (chromosome 2, 11.4–11.6 Mb, 172 genes) and HS7 (chromosome 2, 21.4–21.6 Mb, 183 genes), one or more GO terms associated with CYPs, cysteine proteases or DOGs were enriched, albeit with modestly significant p -values as compared to those for HS1.

To test this, we deleted the core motif of the Inr element in the ceh-51 promoter and unexpectedly found only a modestly significant 21% reduction in the ceh-51 accumulation rate ( Fig. 7C ).

However, the CpG-to-mRNA correlation between them was relatively modest, and although CREBBP formed the central node in the PPI network, the expression of Crebbp was uncorrelated with its cognate CpG, and instead, the Crebbp transcript had a modestly significant inverse correlation with the Hnf1a CpG ( Figure 5f ).

However, despite this improvement, the engrafted mice eventually reached ERC (end-point of the study), in addition, the survival advantage for Jeko-1R was modestly significant.

In contrast, there was no or only modestly significant association when TADs in peripheral tissues were used, with a statistically significant difference in ORs between brain and stem cells and peripheral tissues ( Figure 1 E, p = 2.72 × 10 −5 , two-tailed Wilcoxon rank-sum test).

Consistent with this, uninoculated and aged PINK1 KO and Parkin KO also trended towards higher OCRs for State 3 when compared to uninoculated and aged wild-type mice ( S3 Fig ), although only the State 3 OCR for the aged Parkin KO mice was modestly significant.

The areas under the ROC curve (AUC) of BMI, WC, and WHtR where all modestly significant (all AUC ≥0.65) and nearly identical at 0.6592, 0.65, and 0.6724, respectively.

In Figure 12 (right), for infants possessing NNS results already considered to be in the normal region (quadrant I) before the frenotomy (cases 9, 22, 43, and 73 (in red boxes)), there were modestly significant improvement for cases 9 and 43 towards the mean of the population in our study and no significant change to cases 22 and 73.

For instance, age, hemoglobin level, and renal function showed significant or modestly significant impacts on long-term mortality throughout the follow-up period (stable proportional hazards function).