“modestly significant”

21 In CKD, the adjusted risk ratios of stroke with AF have varied considerably across CKD subpopulations, ranging from 4.2 in women in the general population, 34 1.3 in dialysis patients, 33 , 35 and with modestly significant (1.4) 36 and non-significant 37 associations after kidney transplantation.

We found that only six genes belonged to both sets; this represents a modestly significant decrease of KRP5 targets in our LGOoe -regulated gene set.

However, we consider SV/LAV to be a negative index of LA volume overload that represents another aspect of LAEF under the conditions of preserved LVEF, and a modestly significant correlation was observed between NT-proBNP and the SV/LAV ratio.

Additional analysis of data has showed that in fact, in unstressed cells, XRN1 KD leads to modestly significant reduction in overall transcript length (Fig. 3b, c).

Both ajmalicine and serpentine levels exhibit modestly significant increases in the induced versus uninduced ORCA2-OE cultures 48 h after the start of induction, but are not significantly different at the other time points assayed.

In an analysis, utilising the methods described by Conti et al., [ 20 ] of the simulated data when homocysteine is the causal variable (Table 5 , first column) and incorporating an exchangeable prior structure in which all genes are treated equally (ie intercept only in the prior covariate matrix, Z), the posterior probabilities of including the two modestly significant genes TS and FTD are 0.57 and 0.48, respectively.

It is obvious that any crude multiple-test correction such as Bonferroni-correction would make modestly significant correlations, such as we found them between cardenolide numbers and speciation rate, become non-significant.

There was only a modestly significant relationship between the GIDE and the pretreatment level of ER based on immunohistochemistry; the current data suggest that high ER expression may be necessary for a tumour to be highly responsive (high GIDE) but that some tumours with a high ER have only a moderate or poor biological response.

While one clinical study demonstrated a modestly significant effect on 6MWD and dypsnoea of oral treprostinil as monotherapy when compared with placebo [ 47 ], other studies failed to show an effect with adding oral treprostinil in patients receiving stable background therapy with an ERA and/or a PDE-5i [ 48 , 49 ].

A modestly significant difference in the changes in the Chinese MetS Z score was also observed between the two groups at 3 months (mean difference: −0.25 [95% CI, −0.44 to −0.06]) and 12 months (mean difference: −0.21 [95% CI, −0.40 to −0.01]), but no significant difference was observed at 6 months (Table 4 ).

Up to date, two published GWAS on SB outcomes used a polygenic risk scoring methodology and thereby observed modestly significant overlap of the common SNP risk-allele burden with schizophrenia or major depression [ 10 , 27 ].

Another study utilised the same data set from The Avon Longitudinal Study of Parents and Children (ALSPAC) cohort to demonstrate modestly significant adjusted DORs for conduct and hyperactivity problems and poor GCSE results [ 24 ].

T FM was a modestly significant discriminator.

( 41 ) found two modestly significant correlations between late positive component (LPC) amplitude and psychopathology scales relating to hallucinations after correcting for multiple comparisons.

Subgroup analyses and meta-regression yielded only modestly significant p-values, and considering the lack of a priori hypothesis and the large number of comparisons that were made, they should be considered as exploratory analyses.

The results showed several modestly significant relationships between clinical and cognitive measures, but, following correction for multiple comparisons, only an inverse relationship between the negative syndrome and digit symbol–scaled score remained significant.

Although response rates at week 6 and 26 were found to be modestly significant, induction of remission rates were not.

Finally, the mRNA targets of these small RNAs exhibit a modestly significant differential increase in expression in rrp6Δ compared with the general mRNA population ( Figure 5G ).

Discussion There was a modestly significant reduction in DRP deaths associated with being an initiator that is consistent with the hypothesis that initial treatment contact is effective in reducing DRP deaths.

Regardless, the interpretation of the modestly significant associations should be conservative.

One study [ 78 ] proposed that factors including ABO blood type may also participate in this intricate process, while a recent meta-analysis revealed a modestly significant increased risk of Cag-A-negative H. pylori strain [ 67 – 69 , 73 ] with positively correlated factors, including non-O blood type [ 64 , 78 ] and smoking status [ 63 , 65 ] in PDAC.

However, despite this improvement, the engrafted mice eventually reached ERC (end-point of the study), in addition, the survival advantage for Jeko-1R was modestly significant.

Between-group comparisons: COVID-related change in QoL, STAI, and AUDIT scores QoL : ANOVA indicated that the change score in self-reported QoL was modestly significant among groups ( Fig. 1 ) ( Table 1 ).

By contrast, NREP posited that the internal models should largely compensate for most of these structural deviations, arguing that differences in judgement accuracy and precision would be ‘small’ (modestly significant) or ‘non-existent’ between blind-spot and non-blind spot regions (i.e., small bias and precision effects for the ipsilateral eye in the blind spot location, Fig 6 ).

Among 11 tests of differences in time for predictor variables, only one had a modestly significant P value (0.03).