“modestly significant”

The Rotterdam study 25 constructed a second risk score based on 169 SNPs including the original 53 modelled in our study, as well as a further 116 for whom only modestly significant changes in risks were demonstrated.

When we examined for associations between SCA and SNPs on the 100K chip that reside in or near some previously studied candidate genes, we confirmed a number of modestly significant SNP associations with SCA phenotypes (Table 4 ).

treatment and baseline category, previous use of antidepressants was identified as a modestly significant predictor of outcome category.

In contrast, in line with the hypothesized path, both the total and indirect effects of PeDSs (T1) on bonding difficulties (T3) through the full path of the mediators (P-PTSSs and PoDSs) were modestly significant, empirically supporting the proposed mediational model.

We replicated the association between FTO variant rs9939609 and BMI, weight and waist circumference, which were modestly significant.

We also observed weak but modestly significant correlations in ∆TE rel values when comparing our eIF3 datasets to a ribosome profiling dataset obtained from cells expressing R13P eIF1A , in which discrimination against near-cognate codons or AUG codons in poor context was increased ( Supplementary Figure S7 ).

Although the trait correlation with Slc1a3 proved to be modestly significant, these expression correlation results are quite interesting and could be investigated further along with the finding that Slc1a2 gene expression data correlated with our trait scores in trial 2.

A sex × age interaction was modestly significant for each biomarker modality.

The damaging variant in ALDH2 , rs671, is much less frequent in cases than controls for both phenotypes but is so rare in this largely European sample that it only produces modestly significant results.

Although the effect of the intervention on levels of parental stress was not measured, the intervention lowered parental depression but was only modestly significant, with no statistically significant change in levels of anxiety.

Aβ 1-42 had a modestly significant association with CSF CEC in SH-SY5Y cells but not in N9 cells (Supplemental Figure 6 ).

For Scr, a few subgroup tests yielded borderline or modestly significant differences, yet all subgroups maintained the same direction of effect, and none contradicted the overall finding.

The p values associated with those r values were modestly significant, that is probably a reflection of a modest statistical power in the setting of a small sample.

He found that these learning effects are modestly significant and flow fairly easily internationally.

The associations between the CHA2DS2-VASc score and 30-day mortality for CCU patients with different comorbidities and parameters were revealed in subgroup analyzes. After PSM, the interactions between subgroup factors and the HR for 30-day mortality were modestly significant, except for WBC.

Due to the large number of markers evaluated in a genome-wide scan, signals with small effects and modestly significant P -values are likely to be dismissed after the correction of multiple testing.

Suggestive evidence for interaction of smoking with SNPs at other loci also showed modestly significant opposite association directions in stratified GWAS among smokers and non‐smokers (Table 2 ).

Upon stratification by sub-population, modestly significant prostate cancer biomarkers varied by racial/ethnic group in the age adjusted risk models.

However, of those three, only voter turnout remained modestly significant in the multiple regression analyses.

Normalizing NPPB expression to TPT1 and EEF1A1 gave a modestly significant difference in NPPB levels between failed and non-failed myocardium that is more likely to reflect the true level of expression of NPPB in these two groups.

Although none of the more modestly significant insulin sensitivity loci translated to T2D, rs7219451 and rs322394 nearly reached genome-wide significance.

1 A meta-analysis of randomised controlled trials of individual peer support in mental health services indicated a modestly significant effect of peer support on measures of self-reported recovery and empowerment compared with care as usual, also showing that peer support was associated with a reduction in the relative risk of psychiatric hospital admission of 14% compared with care as usual. 2 A report analysing hospitalisation da

The authors repeated an assessment one year later and showed a modestly significant increase of 1.6 min of moderate-to-vigorous physical activity per day, which could indicate that a broader, longer intervention with more resources is needed.

The treatment with drug alone in the same experimental conditions only showed a modestly significant inhibition of cell viability at 48 hours for MSTO-211H (about 20%) and at 72 hours for NCI-H2452 (about 10%) ( Figure 3A and B ).

A modestly significant enrichment for H3K9me3 and depletion of DNA methylation for the copy number alteration was then reported.