The association was not significant in the subgroup analyses according to the region where the included studies were conducted (Table 2 ), although the estimate was near-significant for those carried out in Europe (RR: 1.10; 95% CI: 0.99, 1.21).
BMI appears to exert near-significant positive causal effects on almost all the LDL metabolites of cluster 1, which are known to be atherogenic.
alvi at LD 50 compared with LD 25 , lower Bombilactobacillus abundance in both paraquat treatment groups, and an increase in Lactobacillus at LD 50 with a near-significant difference between paraquat treatment groups.
Regarding the borderline significance of CRP ( p = 0.067), the post-hoc power evaluation indicates that this near-significant trend is likely a reflection of the inherent biological variability of inflammatory kinetics in severe UTIs, rather than an underpowered sample size.
Although total SCFA levels were not reported, there was a statistically significant increase in plasma isobutyrate and isovalerate levels (and a near-significant increase in plasma butyrate levels) following the omega-3 PUFA intervention, which mirrored findings in the inulin intervention group (Vijay et al., 2021 ).
Sun and colleagues developed a list of single nucleotide polymorphisms (SNPs) affecting sex hormone metabolism, some of which showed significant or near-significant linkage to prostate cancer aggressiveness at diagnosis [ 21 ].
There are indications that the probiotic supported such a transition, with CST 1 showing a near-significant association with the probiotic group.
However, the near-significant association of time to ART initiation with neutralization, while not reaching statistical significance, suggests a potential but less pronounced role of early ART initiation in shaping neutralization responses.
Possibly, we failed to find an error rate switch cost in the MDD group because these patients tended to slow down their responses on SEs, resulting in a near-significant RT difference between MDD and controls on SEs.
A near-significant relationship with surf zone SST was present for the body sizes of the largest males and females of E . braziliensis ( Fig 5F ) ( Table 1 ).
Additionally, a near-significant association was identified within the gene ZMAT4 in participants of primarily African ancestry.
For 3c, the univariate comparison for appropriateness of the amount of information (p=.055), indicated near-significant (but ultimately nonsignificant) difference, with English-language respondents reporting lower perceptions than Spanish-language respondents (see Table 2 ).
As soon as work-related PC was included in the model, however, the across-wave (T1–T2, T2–T3), reciprocal relations between job demands and disturbed sleep disappeared and only near-significant, reversed relations from disturbed sleep to job demands prevailed.
The RR further increased to 1.80 (95% CI: 0.94, 3.45) for those living within 100 m of a drainage path and with household food animals compared to those >500 m from a drainage path and without household food animals; this interaction was near-significant with an interaction P -value of 0.108 (RERI: 0.85; 95% CI: −0.10, 1.81) ( Table 5 ).
In addition, near-significant associations with HIV infection were observed for resistance to isoniazid (OR 1.50, 95% confidence interval [CI] 0.99–2.26) and resistance to rifampin (OR 2.35, 95% CI 0.82–6.24) ( Table 1 ).
Following FDR correction, we identified multiple near-significant and significant associations ( q < 0.25 and 0.1, respectively; Extended Data Fig. 9b,c and Methods ), particularly when evaluating features from the immune activation/exhaustion and wound healing clusters (dedifferentiated TI-1 in PD-L1 TPS ≤ 1% q = 0.23; immune-activated M-2 in PD-L1 TPS ≤ 1% q = 0.16; macrophage/monocytes in PD-L1 TPS ≥ 50% q = 0.06; hMono3 in PD-L1 TPS ≥ 50% q = 0.11).
Contrary to most findings in the field of developmental face perception, only a near-significant age effect is apparent in upright and un-manipulated presentation of stimuli, whereas a bigger difference between age groups can be observed for a condition which removes all but horizontal information of a face.
5 A), while the PERMANOVA results (R 2 =0.12, P = 0.055) suggested a near-significant, moderate treatment effect (i.e., dietary grouping explaining 12% of the multivariate variance captured by the first two principal components).
There were significant or near-significant differences in the use of certain micro-stressors in mice and rats: in particular, food and water deprivation are less frequently used with mice than with rats.
It can be seen that the initial fast growth rate provides a near-significant difference between the two groups of patients, in contrast to the other predictors, suggesting that this predictor may be a candidate for prediction of TTP.
The near-significant difference in cognitive distortions suggests potential clinical relevance, warranting further study with larger samples.
The near-significant correlation between walking speed and alternation rate is the first suggestion in the literature that binocular rivalry may be impacted by walking speed, indicating a potential impact of motor behavior on visual perception Prior research has reported that retinal image motion could cause binocular rivalry alternations [ 24 ].
The near-significant tendency for higher fat digestibility in canola-oil diets is also mechanistically coherent, as lipid digestion relies on emulsification, micelle formation, and bile–lipase dynamics that vary with fatty-acid profile and can become more limiting during enteric insults ( Oketch et al., 2023 ).
5C persisted: pore-water nitrate+nitrite concentrations (Wilcoxon test, P =0.03), total nitrogen ( P = 0.09), and the ( nirS + nirK )/ nosZ ratio in MT data ( P =0.11) differed, or showed near-significant differences, between the outside and inside sample plots.
Although we found a near-significant correlation between hippocampal MD and memory within the MCI group, it was substantially attenuated after including hippocampal volume as a covariate.