Consistent with our DNA-PAINT analysis ( Figure 2 ), this occurred with a near-significant decrease in synaptic full-length gephyrin ( Figure 4B ; Veh = 100.0 ± 7.01%, DZP = 75.16 ± 9.64%; p = 0.0559).
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In the literature
This mirrors its unadjusted OR of 7.37 (p < 0.001) and near-significant adjusted OR (2.84, p = 0.056), suggesting a potent synergistic effect between CACNA1D and CACNA1C , potentially due to their direct roles in calcium channel pharmacodynamics (Linde et al., 2012).
Concerning the first research hypothesis (H1a), the results from ANOVA ( Figure 6 ) reveal a near-significant main effect of the group ( F (3, 46) = 2.706, p = 0.056, η 2 p = 0.150), with participants with natural scenarios as their recovery scenario reporting higher valence ratings than those in the Neutral group.
The addition of smoking to the confounding factors detected a near-significant result (β = −0.34, p = 0.056).
The blastomere size variability in two-cell embryos was near-significant for the group factor ( F 3,180 = 2.56, p = 0.056) but not for the survival factor ( F 1,180 = 1.46, p = 0.23; Figure 7 A) or the factor interaction, according to the two-way ANOVA.
We would like to note that, in adults at baseline, the association between ADHD symptom severity and cortical thickness of the left prefrontal ROI was near-significant (r = -0.40, P = .056).
Lastly, hsa-mir-145 was upregulated in all patient groups and showed a near-significant correlation with survival (P = 0.056), hinting at its possible role as a prognostic factor S1 Fig .
Previous study showed that mucin-degraders (family Prevotellaceae) were enriched in patients with depression and anxiety 47 , and a further subgroup analysis of present study also supported a near-significant increase of Akkermansia in unaffected controls with antidepressant ( n = 5, P value = 0.056) when comparing to those without (Supplementary Fig. 9b ).
A near-significant reduction in time from arrival to the operating room was also evident (91.8 versus 214.2 min, p = 0.056 ).
This study showed that MVC-ISO torque did not change in all conditions, but there was a near-significant, small magnitude decrease in the SS + FR condition (p = 0.056, d = -0.31).
Other aspects of EBNP, such as critical thinking, exhibited a near-significant correlation with professional experience (r = 0.191, p = 0.056) ( Table 3 ).
In our study, a significant ( P < 0.005) correlation was observed between the frequency of URG4 positive cells and LVI, and a near-significant ( P = 0.056) correlation was found with the total score.
It was observed that patients who achieved self-management goals showed greater mean hemoglobin A1c reductions at three months than those who did not (-3.6% and -3.0%, respectively) and that the effect of goal achievement on hemoglobin A1c was near-significant (P=.056).
For ECochG measurements, the median signal threshold was 70 (55–77.5) dB nHL and lay 30 dB higher ( Figure 3B ) compared to the preoperative BC threshold (near-significant moderate to strong effect size, R 2 = 0.48, p = 0.056).
The results from pairwise comparisons using the Sidak correction indicate that these effects are due to a significantly lower accuracy in the economic games compared to the life story task in the Outcome condition (estimate = −0.82, Z = −2.60, P = 0.018), while only a near-significant difference between the economic games and life stimuli was observed in the Belief condition (estimate = 0.75, Z = 1.91, P = 0.056).
We noted near-significant associations of TRIM37 expression with parity ( P = 0.0565) and racial identity ( P = 0.09851), in part due to a smaller sample size (Fig. 1K ).
Multivariable Cox regression analysis identified HapB3 status as a near-significant predictor of reduced DFS (HR 3.77; p = 0.057), suggesting a potential prognostic role independent of overt toxicity or dose adjustments.
When those at risk and with prediabetes, are also considered, diabetes status remained near-significantly different between SCOFF categories ( p = 0.057).
Statistically, a near-significant difference was observed between groups (p = 0.057).
Among sleep-related factors, SW-I was significantly associated with NSIs in the crude model and Model 1, while SW-S was near-significant in Model 2 ( p = 0.057), and SW-IS was a significant predictor in Model 3.
The change rate of granulocyte-macrophage colony-stimulating factor (GM-CSF) differed between the BJIKT and placebo groups, with a near-significant difference observed ( P = 0.0572).
Intra-epithelial CD8 + T cell frequency was significantly reduced in the inflamed mucosa, accompanied by a significant increase in distal CD8 + T cell frequency, while in dysplastic epithelium intra-epithelial CD8 + T cell infiltration showed a near-significant reduction ( p = 0.0578), and proximal CD8 + T cell frequency a near-significant increase ( p = 0.0563).
There appeared to be a near-significant effect on CSF amyloid levels (p = 0.058), which was not statistically significant.
In force cycle 2, the t test indicated a near-significant difference between the plates, with t = −2.12 and P = .058.
A near-significant Production by Language interaction was shown ( F (1, 56) = 3.74, p = .058, η 2 G = .006, η 2 p = .06), such that recognition accuracy was marginally greater when speaking aloud in German compared to speaking aloud in English ( Spoken German : M = 3.28, SE = 0.305, 95%CI = [2.671 3.89], Spoken Engli