However, the strongest association of severe SGA with cause-specific mortality was noted for death due to infection (HR = 3.19 in the population-based analysis and HR = 4.24 in the sibling-based analysis), followed by neurologic disease (HR = 2.22 in the population-based analysis and HR = 1.97 in the sibling-based analysis) and injury (HR = 1.32 in the population-based analysis and HR = 1.43 in the sibling-based analysis), although some associations were of borderline significance in the sibling-based analyses.
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“of borderline significance”
In the literature
Baseline BMI and ART enrollment year were of borderline significance in the complete case model, but the variables were no longer significant following imputation.
Sixth, despite our extensive sensitivity analyses, the potential for residual horizontal pleiotropy cannot be fully excluded particularly for associations of borderline significance.
Such an observation was also of borderline significance in the univariable analysis in a study by Nastoupil and colleagues considering patients treated with axi-cel [ 15 ].
The study further confirmed that use of a PPI or statin significantly decreased the risk of progression to HGD or cancer, while the protective effect of NSAID use was of borderline significance [ 47 ].
By immunohistochemistry, we also observed a reduction in the number of macrophages infiltrating both OCI-Ly1 and SUDHL6 tumors, but this was statistically significant only for SUDHL6 tumors, and only of borderline significance for OCI-Ly1 ( Figure 5 B).
A standalone study, in 2024, undertook an investigation into the asymmetry associated with the acetabulum using acetabular articular cartilage surface areas for the assessment of acetabular fractures, and reported a difference of borderline significance [ 32 ].
Of the included ten prospective cohort studies, Only one study adjusted vitamin D and vitamin D supplementation when the effect of coffee intake on hip fracture was analyzed quantificationally [ 15 ], and in that study the estimate of association between coffee intake and hip fracture was of borderline significance (OR 0.88; 95% CI 0.78 -1.00).
In the first years of the period considered, a positive association between PAC and abortion emerged, although of borderline significance due to the small number of cases; the PR was 1.08 (95%CI: 0.92–1.26) in 2010–2012, 1.21 (95%CI: 1.03–1.42) in 2013–2015 and 1.17 (95%CI: 0.98–1.40) in 2016–2018.
In subjects with self-reported CVD the nighttime railway effect estimates for SBP and DBP per 10 dB(A) were of borderline significance (SBP, β = 2.14; 95% CI: –0.74, 5.0; DBP, β = 1.11; 95% CI: –0.49, 2.7).
As, in our data, women were designated as pre- or postmenopausal relying only on their age, we have evaluated whether there is an interaction between age and growth pattern with respect to breast cancer risk, and the results were of borderline significance ( P ∼0.06).
Resting energy expenditure, total physical activity, and moderate to vigorous intensity physical activity were marginally higher in the group assigned to the low carbohydrate diet (group differences or linear trends of borderline significance), with contrasting within group changes in some cases; whereas sedentary time and skeletal muscle work efficiency did not differ by diet ( table 3 ).
We further noted a statistical trend of borderline significance for a greater risk of premenopausal breast cancer in daughters with increasing birth length (p for trend = 0.06; Table 4 ).
When excluding the study conducted by Kreiger et al, 23 an increased risk of borderline significance was found (RR = 1.12, 95% CI 1.00–1.24).
To explore the prognostic potential of the proteomic targets, we used classification and regression trees (CART) to identify patterns of proteins that would robustly classify STS from LTS using the significant proteomic targets; for classification, we used the 7 significantly differentially expressed proteomic targets, as well as YWHAQ, which was of borderline significance.
The variations were of borderline significance and based on small numbers of cases (21 expected cases in January).
In the absence of tone, SHR vessels had a reduced lumen diameter although this was of borderline significance.
observed that clinical bulky (≥2 cm) mediastinal lymph nodes was of borderline significance in predicting an increased risk of BM in IIB–IIIB NSCLC after multimodality treatment.[ 10 ] Wang et al. reported that a greater number of mediastinal lymph nodes and nodal regions with metastases predicted a higher risk of BM for stage III-N2 NSCLC.[ 13 ] Mamon et al. reported that the incidence of BM increased independently by the presence of residual nodal disease in 177 surgically treated IIIA (N2) NSCLC with/without neoadjuvant/adjuvant therapy.[ 11 ] In our study, on multivariate analysis, LNR ≥ 30 % was associated with an increased risk of BM and BM as the first relapse.
There were no significant treatment effects identified in the intervention school children’s mean psychosocial scale QOL and mean overall QOL compared to the control school (Table 3 and Figure 2 ), however trends suggest a treatment effect of borderline significance from baseline to post-test (7 weeks) (Table 3 ).
Thus, while the G84E mutation was associated positively with many of the cancers individually and with all cancer typess in an overall test, the cancer-specific effects were of borderline significance or non-significant ( Table 1 ).
Patients with pT1 stage tumors (HR: 2.04, p -value = 0.0159) and high-grade tumors, according to the 1973 WHO classification (HR: 1.83, p -value = 0.0522), had a higher risk of recurrence, although the latter association was of borderline significance.
For the virgins, none of the risk factors was significantly associated with trichomoniasis, but the association with use of soap (not always versus always) and type of toilet used (pit latrine/bush versus flush toilet) was of borderline significance.
They found a difference of borderline significance in the distribution of the 157insMTTTVP insertion between patients and controls ( p value 0.037), with an allelic frequency of the insertion of 37% in patients and 28% in controls.
None of the attitudinal or belief scales were significantly associated with test selected, although the fatalism and gender-equity scales were of borderline significance.
The association of anti‐HTLV‐I seropositivity with mortality from all non‐neoplastic diseases (RR=1.40) and chronic liver diseases (RR=5.03) was of borderline significance.