Barely Significant
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“showed a trend”

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In the literature

The adjusted mean HDL levels in patients with a combination of periodontitis (−) and bacterial burden (low, moderate, and high) and periodontitis (+) with the presence of bacterial species (low, moderate, and high) were decreased ( p for trend < 0.5), while TG levels in those groups showed a trend to increase ( p for trend < 0.5) as shown in Fig. 3 .
Although none of the biomarkers tested predicted response to sorafenib, patients with high s-c-KIT or low baseline hepatocyte growth factor concentration in the sorafenib cohort showed a trend towards enhanced benefit. 69 , 70 The ALICE-1 study looked at VEGF and VEGFR genotyping to predict outcomes with sorafenib and identified several polymorphisms (single nucleotide polymorphism [SNPs]) of VEGF that influenced PFS and OS. 71 The ALICE-2 study also showed SNPs of hypoxia-inducible factor-1α (HIF-1α) to be significant for PFS and OS.
According to the results of our evaluation of MM cases that excluded t(14;16)-positive cases and cases not evaluated for genetic/cytogenetic abnormalities, good responders to Bd therapy expressed more NCAM than did poor responders, and the differences in NCAM expression between the two groups showed a trend towards a difference.