“showed a trend”

Similarly, for patients identified as high-risk, we observed no statistically significant difference in DRFS between HER2-positive or HER2-negative patients ( p = 0.09), although we did observe that HER2-positive patients showed a trend for worse outcome.

While control mice treated with CNO showed a trend for increased food intake on chow ( Fig. 8 G ), they showed an almost 3-fold increase feeding on HFD ( Fig. 8 H ), suggesting a preference for HFD feeding on activation of VTA LepR neurons.

Overall, the growth kinetics results showed a trend similar to that observed with the vRNP reconstitution assays.

Although it did not reach statistical significance likely due to short follow-up time, recent population-based study showed a trend towards improved overall survival in young women with stage IB cervical cancer who had ovarian conservation as compared to those who had oophorectomy [ 5 ].

Moreover, pharmacodynamics (PD) analyses using patient-derived mononuclear cells from day 1 (pre-treatment) and 28 (post-treatment) in six patients showed a trend towards decreased phosphorylation of 4E-BP1, a downstream substrate of mTOR (data not shown).

74 A recent RCT in patients with non-diabetic CKD showed a trend towards slower decline in renal function in patients on Beraprost compared to placebo. 75 Riociguat Riociguat is a novel treatment for PAH that stimulates the soluble guanylate cyclase in vascular SMCs.

The remaining two settings also showed a trend toward better low contrast depiction with NIP.

2h ), and neurons inhibited by photoidentified BLA→PL neurons (“Network Inhibited Cells”) showed a trend towards increased excitatory responding to the reward-associated cue or inhibition to the shock-predictive cue.

Hematological parameters showed a trend of increased high-density lipoprotein level and decreased total cholesterol level in the ChS500 Group compared to the groups receiving the extract at lower doses.

In all time groups, the ε-Fmax did not significantly change with respect to the initial value but showed a trend of increasing values.

Tumor marker studies in ovarian cancer patients showed a trend of decreasing Cancer antigen 72-4 (CA 72-4) aka tumor-associated glycoprotein 72 (TAG-72) and tumor growth with increasing administered radioactivity.

As shown in Figure 1 , the incidence of bacterial isolation showed a trend of decreasing at first, and then climbed up along with age.

Although neither trial reported a significant effect of A 1 -PI therapy on pulmonary function, CT analysis showed a trend towards a more favorable effect of treatment, which was suggestive of lung tissue preservation compared with placebo.

In the wound area photon emission measured at 6 hours time showed a trend to increase in animals treated with both 1e and 1f (30% and 20% increase with respect to time 0, respectively).

Summary of Change across All Symptom Measures Visual comparison of the means between pre-therapy and the end of therapy for the whole group indicated that overall the sample showed a trend for improved scores on all symptom measures, which appeared to be maintained at 6-month follow-up (Table 3 ; Figure 3 ).

Two measures, pronoun use and independent self-construal, showed a trend in the predicted direction, with participants primed with solitary activity shifting towards more independent responses, and participants primed with collective activity shifting towards more interdependent responses, although as just noted neither of these shifts were statistically significant.

With regard to other AT depots studied, although no significant differences were found among experimental groups, FRD mice showed a trend toward increased IAT and RPAT mass, which was not observed in FRD-Lk mice ( Figure 1 D,E).

Interestingly, only patients with normal gastric emptying had significant improvement in their glycemia while patients with delayed gastric emptying at the start only showed a trend for reduction in postprandial glycemia.

The relative level of total MEK was also increased, while the level of total ERK as well as the ratios of p-MEK to MEK and p-ERK to ERK showed a trend of increase ( Fig 4 ).

The responses to CS (cue) quickly appeared and became largely stabilized, whereas the response to US (quinine or footshock) even showed a trend of further increase.

Joint pain Most of the studies included in the present review showed a trend toward improvement in pain intensity for the resistance training group.

Although the main effect of target did not reach significance, it showed a trend in which the mean F 0 of the participants progressively increased in responses to the neutral (mean ± s.e.m. = 156.17 ± 2.05 Hz), dominant (156.75 ± 2.27 Hz), and prestigious (157.10 ± 2.25 Hz) targets ( Table 2 ).

ASC responses across both groups showed a trend to associate with peak serum antibody responses at day 84, but this did not reach significance ( Figure 5B ).

Finally we studied the permeability of JIB 04 across the blood-brain barrier and found that this molecule reaches bioactive concentration in the brain; furthermore a pilot in vivo experiment in an orthotopic GB xenograft model showed a trend toward longer survival in treated mice with an Hazard Ratio of 0.5.

Although cortisol concentrations during the ACTH test showed a trend towards decrease after seven days, they did not reach statistical significance.