After further adjusting the model for following a GFD for at least 18 months, there were no statistically significant differences but CD children showed a trend close to signification indicating a higher percentage of energy intake from UPF among celiac compared to controls ( p = 0.056).
Penetrating disease (B3) increased the surgical risk (HR, 5.454; 95% CI, 1.094–27.178), and structuring disease (B2) showed a trend toward an increased risk of surgery ( P =0.056).
Surprisingly, we found that in areas surrounding neuronal cell bodies, the number of PSD-95 and SHANK1 puncta showed a trend towards a decrease in Tmem184b -mutant mice (p = 0.056 for SHANK1) (Supplemental Fig. 3 in Additional File 1 ).
When we compared clinical characteristics between the two groups, before SST, the ADHD group showed significantly higher CRS scores than the ASD group (p=0.040) and, though it was not statistically significant, showed a trend for higher ARS scores (mean score ADHD=25.33, ASD=19.63, p=0.056).
In addition, the correlation between vascular tumor invasion and OS showed a trend for significance ( P =0.056).
Furthermore, MYD88 , the key downstream adaptor for TLR signaling, showed a trend towards upregulation (median FC was 0.78 and 1.33 in the younger and in older groups, respectively; p = 0.056).
Myocardial tissue characteristics Myocardial native T 1 did not change on marathon running, while myocardial T 2 showed a trend towards a small reduction post marathon (p=0.056).
SAE risk was not significantly elevated for Resmetirom (RR: 1.11, 95% CI: [0.77; 1.59], p = 0.58), but GRAs showed a trend toward higher SAE rates (RR: 2.38, 95% CI: [0.98; 5.82], p = 0.056).
Questionnaire A TG patients showed a trend towards a younger mean age at cancer diagnosis of 45.3 years (S.D. = 1.57) compared to the NTG with a mean age of 52.3 years (S.D. = 3.79) ( p = 0.056); this difference appears remarkable, but not statistically significant.
Baseline PINP showed a trend toward predicting post-intervention levels ( p = 0.056).
Taken as a composite, in the groups where cells were transplanted into mice without extended culture (Unexpanded), NUP98-HOXA10HD showed a trend toward higher engraftment compared to the untransduced Mock group (p = 0.056) and a statistically significant higher engraftment compared to the control GFP transduced group (p = 0.0002) ( Fig 5a ).
MIBG myocardial scintigraphy indices showed a trend toward higher early H/M ratios in cluster B ( p = 0.056, Cohen's d = 0.68), whereas delayed H/M ratios and washout rates did not differ significantly across clusters. 4 Discussion In this questionnaire-based study of Japanese outpatients with PD, chronic sialorrhea was common and was associated with male sex, longer disease and treatment duration, greater motor severity, and a substantially higher burden of autonomic symptoms.
Piglets from sows supplemented with tributyrin showed a trend for higher feed intake immediately post-weaning ( p = 0.056).
26.7%; χ 2 = 4.54, P = 0.033) and showed a trend towards higher alcohol misuse as well (43.7% vs. 30.4%; χ 2 = 3.64, P = 0.056).
Besides, treatment with UAMC-00050 significantly increased elastase-like activity measured with Suc-Ala-Ala-Ala-AMC (Bonferroni-corrected unpaired t -test p -value = 0.006, Figure 7E ) and showed a trend towards an increase in elastase-like activity measured with Suc-Ala-Ala-Pro-Val-AMC in fecal samples from acute colitis rats (Mann-Whitney U two-sided p -value = 0.056, Figure 7D ). 4 Discussion In this study, we provide new evidence for serine protease inhibitors such as UAMC-00050 and nafamostat as promising therapeutic agents for the treatment of visceral hypersensitivity.
At the maximum serum drug (C max ) concentrations tested, significant differences in killing rates between the compounds tested were not seen following the first 5 min of drug exposure; however, pradofloxacin (6.6 log 10 99.9% kill rate) showed a trend toward a significant difference as compared to tildipirosin (growth, p = 0.0561) ( Figure 3 ).
Four months post-transplant, analysis of the superficial cervical LNs showed a trend in that all MPTP-treated mice had larger LNs compared to control animals ( P = 0.0561) (Fig. 4 a).
Valine showed no significant correlations, although its association with FIM-cognitive showed a trend ( p = 0.0563).
Corpus Callosum Within the corpus callosum the mRNA of stem cell marker Nestin showed a trend towards a downregulation in the G-CSF treated group ( p = 0.0563), whereas SOX2 ( p = 0.0239) and MSI1 ( p = 0.0152) were significantly downregulated, as shown in Figure 5 .
Protein analysis at 72 h post- LOXL1-AS1 knockdown showed a trend toward a decrease in MLC activity ( P = 0.0563) ( Fig. 5 ).
And the SHR 1 g/L group showed a trend towards a lower left atrial dimension (LA) level ( p = 0.0563, Figure 3(h) ). 3.6.
Results CRISPR/Cas9 treatment targeting miR-21 showed a trend toward reduced miR-21 expression (p = 0.0563), although this did not reach statistical significance.
“Taurine and hypotaurine metabolism” showed a trend towards enrichment (one hit out of 8; raw p = 0.0565; FDR = 1.0; impact = 0.43), consistent with the prominent taurine signal in A. lixula spectra ( Figure 1 ).
Similarly, copeptin showed a trend ( P = 0.0565) towards a 19% improvement of net reclassification for patients at the highest risk of 90 day mortality or rehospitalization (95% confidence interval [−0.5, 39.1]).
Surprisingly, PD patients did not show any deficit of their JND compared to healthy controls, although the results showed a trend ( * p = 0.0565, n = 40).