20 In our study, concurrent CRT showed a trend toward improving the complete response rate, PFS and OS, but there was no significant difference between sequential group and concurrent group.
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Additionally, combination treatment was superior to treatment with liraglutide and showed a trend to towards superiority to KBP-089 alone (Fig. 1 d).
All three cell lines showed a trend of increasing fraction of cells in G2 with increasing dose of ionizing radiation.
Rock masses encountered many dislocations and the mountain showed a trend of potential overall slope failure.
In addition, there is no statistically significant difference at pre-index viral load; it showed a trend with much lower pre-index viral load over time.
Correspondingly, these SP-swapped viruses showed a trend of or a significant increase in V2i mAb resistance vs WT: the cumulative neutralization AUC values decreased by 87 and 188 for 293T-derived CMU06-398F1 and CMU06-271.1, respectively, and by 125 for PBMC-derived CMU06-271.1.
The PaO 2 showed a trend toward faster recovery at t = 5 min after d-amphetamine administration but it did not reach statistical significance (saline: 57.7 ± 12.0 mmHg, d-amphetamine: 75.4 ± 14.6 mmHg, p = 0.0501, n = 9).
Moreover, in accordance with the observed effects on TEER after HDM exposure, acetate showed a trend towards recovery of the ZO-1 expression via ERK1/2 signalling pathway suppression.
Indeed, weekly E2 PLGA treatment resulted in improved spatial working memory on the WRAM task and showed a trend in improved spatial reference memory on the MWM task relative to control treatment, whereas free E2 treatment did not impact spatial learning and memory relative to control treatment.
Regarding the duration of cupping therapy, our results showed a trend that 5-min cupping therapy increased more SBF than 10-min cupping therapy.
All patients showed a trend to the normalization of sagittal alignment, whatever subgroup they belonged to.
Moreover, results showed a trend (which also failed to achieve statistical significance) of a greater number of late apoptotic cells in a dose-dependent manner compared to the control group following treatment with DAV extract ( P > 0.05; Fig. 6 c).
In agreement with the changes in the immune cell populations, protein extracts of pancreas showed a trend toward decreased expression of COX-2 ( Figure S2D ), although not statistically significant, possibly due to the variation between animals.
In general, all these circuits showed a trend towards increasing multistability, with the strongest effect seen for the GRHL2 circuit ( Figure 3 B).
It can be seen that during the period from 2014 to 2018, the average level of media coverage generally showed a trend of first decline and then rise, and the standard deviation (SD) data also showed a decline first and then rise, which shows that Chinese media organizations have different trends in the number of environmental news reports of different companies.
Follow-up echocardiography was performed on eight patients at a median interval of 9.2 months (IQR, 2.1–13.2 months) and showed a trend of decreased prevalence of LVH and left ventricular (LV) mass.
Furthermore, BLM treatment increased expression levels of the ECM genes Col1a1 , Col3a1, and Fn, and these levels showed a trend of further increase in heterozygous and homozygous mice treated with BLM as compared with wild-type mice treated similarly ( Figure 8 C–E), suggesting that h IGFBP-5 transgene expression potentiated the response to BLM. 2.8.
The present study showed a trend toward a better outcome after relapse when it occurred more than 12 months after diagnosis.
Interestingly, while these in silico data only showed a trend toward reduced expression of MIF in the skin of DLE patients, they dismantled a similar pattern of expression and correlation with inflammatory infiltrates of the MIF homologue, DDT.
Administration of CB1R agonist in the GHS-R1A knockout mice did not influence the food intake contrary to the wild/control mice, which showed a trend to increase food consumption with higher doses of HU210 injection [ 30 ].
The fact that despite the increase in SMA and diminished pro-UPA activation CTSB ko mice showed a trend in higher—than rather lower—outflow facility and no significant morphological or physiological changes in the outflow pathway tissues was somehow a little disappointing and unexpected.
The Gd 5 Ge 2 Si 2 alloy and pure Gd showed a trend of development of MCMs.
The properties of the binary blends as a function of time showed a trend similar to that observed for TPS alone; this finding indicated that the TPS/PCL interactions were not strong enough to affect the structural changes in the TPS, which continued to occur regardless of the PCL content.
Densitometry analysis of the blots in comparison with WT controls showed a trend toward higher signal intensity of active cysteine proteases in Ctsk -/- mice, although this did not reach statistical significance ( Figure 5 C).
The data showed a trend towards increased translation efficiency changes after H 2 O 2 treatment with higher tryptophan codon content, which was not observed in other stresses (Figure 6C and Supplementary Figure S10A–D ) or in other codons ( Supplementary Figure S10E, F ).