Although the pilot study was not designed to detect a statistically significant difference in BP, the S+Q group showed a trend toward a clinically meaningful decrease in BP at the end of 5 weeks compared with the other groups.
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Ewes in the FR and GA treatment groups showed a trend to decrease BW during the experiment in comparison with the CO ewes (BW (kg): CO initial 79.13 ± 3.01 to final 78.3 ± 2.63; GA initial 80.37 ± 3.01 to final 75.53 ± 2.7; FR initial 80.8 ± 2.69 to final 74.67 ±1.87; Fig 1 ).
Lysophosphatidylcholines C16:0 ( P = 0.01), C16:1 ( P < 0.01), C18:1 ( P = 0.04), C18:2 ( P = 0.01) were decreased in PP cows, with the exception of C17:0 ( P = 0.09) which showed a trend of increase.
All three groups showed a trend of increase in NH 3 flux from June to September.
However, many indicators, including palmitic acid, stearic acid, oleic acid, linoleic acid, and linolenic acid, showed a trend of “down-up-down.” With the development of plants and the maturation of fruit, fatty acid, protein, fat, and other nutrients continue to increase.
Exploratory analyses showed a trend for higher reactogenicity in the 60-Alum group as compared with the nonadjuvanted groups.
The wetland area showed a trend of first decreasing and then increasing, reaching a minimum in 2010 (202.12 km 2 ), which was mainly due to precipitation and beach reclamation.
Many of the aldehydes in the chocolate system showed a trend of low (in some cases nearly zero) relative abundance increasing at each successive time point up to 24 h (Fig. 5 K).
The Medac scheme showed a trend for reduced overexposure compared with dosing in our study.
14 Univariable logistic regression analyses of the probability of being a responder as a function of exposure (both AUC 0–336 h and C trough,sd ) showed a trend toward a positive association ( Figures 3 a and S2 , Table 1 ), and 95% CIs for the OR overlapped 1.
We also showed a trend toward improved pain control with the >0.25 mg/kg dose at the expense of prolonged emergence.
11 A recent survey of spine surgeons showed a trend toward delaying surgical decompression in complete SCI compared with incomplete SCI. 12 , 13 Upper thoracic SCI are more often complete with less potential for meaningful neurologic improvement believed to be due to the tenuous blood supply in this region as well as the high-energy mechanism needed to create an injury due to the stability of the chest wall and spinal column in the region.
23 , 24 Our results also showed a trend toward a lower median exposure in patients weighing < 30 kg; however, a target AUC for efficacy was not determined in a previous study and lower AUC (< 40 mg*hour/L) did not impact on treatment success. 22 Exposure‐response efficacy analyses showed no relationship between systemic anidulafungin exposure measures and global response or all‐cause mortality at end of i.v. treatment, EOT, or EOS.
The results showed a trend toward more lipid content in treated cells compared to untreated cells, although not significant due to the large cell to cell variance.
Similarly, for MMR and MR4.5, the e13a2 group who received imatinib 400 mg daily showed a trend of a lower response rate compared with the groups of patients treated with other TKI approaches.
Although the speed of total land consolidation is not especially rapid, most of the counties showed a trend of increasing homogeneity and concentration over the past three decades.
30 Their overall consensus was that IBD patients showed a trend toward higher risks of developing hematological malignancies, more specifically leukemia in UC and lymphoma in CD based on large population-based cohort studies.
APOE 4 non-carriers showed a trend toward greater CSF DHA levels and significantly greater EPA levels compared with APOE 4 carriers.
Exploratory whole‐brain analysis showed a trend toward a significant positive association between sleep duration and FA in several white matter tracts including the SLF, the corticospinal tract, the thalamic radiation and the internal capsule ( p fwe = .056, for further details see Supplementary Material 10 ).
Conversely, subjects with severe LAP showed a trend towards hypomethylation of upregulating genes when compared to healthy controls and subjects with moderate LAP, suggesting increased expression of pro-inflammatory cytokines that promote further periodontal tissue destruction.
Notably, it also emerged that many “old” drugs targeted already targeted proteins; by contrast, new effective drugs used in combined therapeutic treatments showed a trend toward more functionally different targets.
It was shown that after acute administration of sildenafil or vardenafil (1–100 μg/kg, intravenous) PVP remained unchanged or showed a trend towards a decrease.
Moreover, the flow curve showed a trend of gradually decreasing in each pass.
While the mMCP-6-deficient mice only showed a trend for reduced ear thickness at day 14 ( Figure 6 a), a small but significant difference in ear thickness at day 14 was observed and CPA3 −/− mice as compared with wild type littermate mice ( Figure 6 b).
miR-206 showed a trend with higher levels in OPMD (pFDR 0.06) ( Figure 3 B). miR-206 is also upregulated in other muscular dystrophies [ 9 ]. miR-1, a common muscular dystrophy biomarker [ 9 ], was not significantly deregulated in OPMD ( Figure 3 B).