Overall, 25 genes showed a trend of difference in at least one of the test substrates, and of these, the majority, 18 (72%) were downregulated in TG mice, identified in bold in Fig. 1 A.
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Notably, the systolic septal and diastolic inferior wall thicknesses showed a trend toward a decrease in the sham-operated females compared to sham-operated males (Table 1 ).
The relationship with air pollution variables The time evolution of the concentrations of the pollutants analyzed, PM 10 and NO 2 , clearly showed a trend of decline, which could be explained by the restrictions on mobility that took place in Madrid after the declaration of the state of alarm on March 14.
As tissue samples showed a trend towards higher TMB and enabled the detection of slightly more POL variants compared with ctDNA samples, tissue samples were included in the final analysis for patients with both tissue and plasma samples available.
In line with this observation, comparisons of characteristic stem-like and exhaustion markers between the two treatment groups showed a trend toward higher expression of stem-like markers in cells from spleen_combi than those from spleen_vac ( figure 5G ).
CD8 + T central memory cells (CD8 + T CM ) showed a trend that did not quite reach statistical significance after Benjamini-Hochberg correction (FDR=0.11) ( Figure 6F ).
Within each 6-month MHD group, mean 6-month MSQ-RFR showed a trend towards lower MSQ-RFR with higher 3-month (prior) MHD category.
However, all showed a trend toward recovery of kidney function after completion of treatment.
Blood Cell Viability correlated with ICH volume, and pyroptosis of macrophages [ 70 ] showed a trend toward activation (Table S7 A).
“Most suitable” and “Suitable” areas for potato cultivation showed a trend towards northward expansion.
We also found that AMF showed a trend in decreasing biomass in response to drought, similar to previous studies 42 , but without any change in composition in single drought 42 – 44 , whereas a clear shift was visible after 10 years of recurrent drought.
Furthermore, with PLX3397 treatment, response to CO 2 (a vasodilative agent) showed a trend towards impairment (Fig. 7e–f ), suggesting that microglia regulate both blood flow dynamics and are necessary for at least some aspects of vascular reactivity.
In addition, the neuropil Shank3 IR showed a trend of loss of the laminar variability in the age/AD cases relative to the youth/adult cases ( Figures 1E–L , 11A–D).
Meanwhile, the scale of older migrants with NCDs also showed a trend of increase.
Slices obtained from older animals showed a trend toward higher spontaneous activity levels ( Figure 3A , Figure 3—figure supplement 1A, B ) and significantly lower mitochondrial motility than slices obtained from younger animals ( Figure 3B , Figure 2—figure supplement 1A, B ).
OB/OP staining predominance showed a trend towards association with moderate or frequent CERAD score but was not significant (82% AON predominance versus 62% peripheral, p = 0.07).
Furthermore, in the D178N group, 129VV patients were younger at disease onset and showed a trend toward a shorter disease duration than 129VM carriers (Supplementary Table 6, online resource).
In this study, our results showed a trend that irradiating mice in the early pathological stage of AD was more effective to treat AD than those in the late stage (Fig. 2d, e, g, h ).
In a post hoc analysis of baseline features, a trend to predicting a response in MEP was limited to a lower baseline MEP value and only older age showed a trend to predicting a response in the 6MWD.
The subjects also showed a trend toward high socioeconomic status (SES) based on the assessment of perceived economic well-being and parental education level.
“Burned-out” patients also showed a trend toward a higher incidence of extra-pulmonary visceral metastases, although not statistically significant ( p = 0.0632); the presence of such secondary lesions is a documented poor prognostic factor in adults ( 12 ) but not in the pediatric population at the state of the art.
LV diastolic dysfunction as assessed by E/E’ showed a trend towards improvement in inactive disease group, a significant improvement was reported by Bruch C et al. 8 Flow mediated dilatation of brachial artery was significantly less in disease active patients as observed by Brevetti G et al. 3 The precise mechanism of endothelial dysfunction in acromegaly is not well understood.
On the 7th day after birth, the tendon tissue structure was determined and showed a trend of difference in terms of collagen fibril diameter.
Similarly, cell density measured from the density of DAPI (nuclei) staining at day 7 of culture showed a trend similar to that of the cell proliferation ( Fig. 4 G).
Discussion After the implementation of the NHCSR, the JS of VCDs showed a trend of first rising and then falling.