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“showed a trend”

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Identification of 16 patient clusters (RankClusters) based on the Bayes Mallows clustering The grouping results obtained for 16 clusters showed a trend that samples cluster according to organ site, confirming that tissue of origin is a strong determinant for global gene expression profiles and phenotypes (Fig. 3 ).
Patients with multiple primary cancers (PaMC and NPaMC) with variants in MLH1, MSH2, MSH6 and PMS2 showed a trend consistent with various LS-related cancers ( Geary et al ., 2008 ; Kastrinos et al ., 2009 ; Weissman et al ., 2012 ; Win et al ., 2012 ; Møller et al ., 2018 ; Gambichler et al ., 2021 ), although whether they had LS was unknown (Supplementary Table 3, Supplemental digital content 4, http://links.lww.com/EJCP/A383 ).
Similar to results from the substitution and insertion experiments, ePE3 (H840A) and ePE3 (H840A + N863A) induced the same frequencies of the correct deletion (on average, 49.6 ± 5.0% and 48.4 ± 5.4%, respectively), but the frequency of unwanted indels induced by ePE3 (H840A + N863A) showed a trend to decrease at the five loci (Fig. 5g and S 7C ).
25 previously reported five ROIs that showed a trend of decreased INT in SZ compared to TD (right occipital fusiform gyrus/U_rOccFusG, left superior occipital gyrus/U_lSupOccG, right superior occipital gyrus/U_rSupOccG, left lateral occipital cortex/U_lLatOccC, right post-central gyrus/U_rPostCenG), two of which were replicated, in ref. 25 , across three independent datasets, namely the U_lLatOccC and the U_rPostCenG.