“showed a trend”

The results indicated that Seltorexant holds the most promise for therapeutic efficacy in treating MDD, Suvorexant showed a trend toward improvement, while Filorexant yielded less favorable outcomes ( Meshkat et al., 2025 ).

However, in subgroups with impaired liver function, including patients classified as Child-Pugh class B or ALBI grade 3, dual therapy showed a trend toward better prognosis.

In Model 1 and Model 2, the WO, SO, and HSO groups showed a trend toward shorter sleep duration compared to the NO group, with differences in the WO and HSO groups being marginally significant.

Coverage analysis revealed that Settings 2 and 3 were able to use most of the demultiplexed reads to call the haplotype (i.e., trend close to a slope of one), while Setting 1 showed a trend with a slope close to 0.5 instead of close to one (Figure 4A–C ).

35 Interestingly, although we did not observe a statistically significant positive correlation between phlegm-dampness constitution score and BMI ( Figure 5B ), individuals with a phlegm-dampness constitution showed a trend toward lower antibody production, albeit without reaching statistical significance (Supplementary Figure S1).

Although not statistically significant, the PMI showed a trend toward higher values in the CKD-I group.

Instead, anaerobic coverage was significantly associated with higher acute GVHD incidence and showed a trend toward increased GVHD‐related mortality.

In TS patients, mean IoR showed a trend to positive values.

In sex‐stratified models, the magnitude of change in AUC for men and women was only statistically significant among men for the CAIDE model and showed a trend for improvements for the FRS% model (Table 2 ). 3.2 Ten‐year incidence of NfL positivity The AUC for prediction of incident NfL positivity using the CAIDE score and FRS% were 0.68 and 0.69, respectively.

A larger randomized controlled trial investigated it as a prophylactic and found that while it did not significantly reduce the incidence of infection, it was associated with a higher self-reported quality of life during the pandemic period and showed a trend towards promoting faster recovery in those who did get infected (Kulkarni-Munshi et al. 2025 ).

Notably, even a more refined method based on subtraction maps between post- and pre-LITT scans [ 2 , 3 ] yielded an estimated extent of ablation that only showed a trend toward being more radical in responders (not a significant statistical association).

Both antibodies showed a trend towards higher brain retention in Tg-ArcSwe mice and [ 125 I]1101-scFv8D3 showed a higher brain-to-blood ratio compared to [ 124 I]1101.

Findings Salvia heldreichiana essential oil significantly reduced serum cortisol levels ( p < 0.05) and showed a trend toward increased hippocampal serotonin levels, similar to diazepam.

This included two members of the complexin family, CPLX1 and CPLX2, which both showed a large decrease in 3xTg mice as well as SYN2 which only showed a trend towards a moderate loss.

Authors finally concluded that both objective and subjective measures showed a trend to a higher depth-of-focus for Symfony and Synergy IOLs compared to most trifocal diffractive designs, with the exception of the PanOptix IOL.

Although only one RCT by Lui et al. 21 demonstrated improved detection of SSLs in the Endocuff+AI group compared with the AI-alone group, our study showed a trend toward a higher SSLDR with the Endocuff+AI group, although it was not statistically significant.

A retrospective study analyzed the intrapatient heterogeneity of 18 F-FES PET as a prognostic factor in 102 patients with mBC and demonstrated that patients with ER-positive homogenous expression showed a trend toward longer outcomes as compared with those with heterogenous expression [ 10 , 11 ].

As the amount of NaCl added increased (0% → 2% → 8.92%), the BD of F100 and F50 remained statistically unchanged at lower NaCl concentrations (0–2%) but increased significantly at higher levels (4.46% and 8.92%) ( p < 0.05), while the BD of F0 showed a trend of first increasing and then decreasing.

Similarly, in the L30 group ( Figure 3 G), genes including igfbp1 ( p = 0.0828), igf2bp1 ( p = 0.0698), and sstr2b ( p = 0.0810) showed a trend of downregulation. 2.4.

The groups were also sorted based on functional pathways ( Figure 5 D–F), where microglia showed a trend of predicted activation in the TBI + PBS/sham group in phagocytosis, endocytosis, microglia activation, and immune response of cells, which was inhibited by EV treatment.

Under drought stress, the expression levels of MdNLP2 , MdNLP3 , and MdNLP5 in apple showed a trend of first increasing and then decreasing [ 49 ].

Following initiation of therapy, both patient-reported and parent-reported outcomes showed a trend towards improvement and subsequently remained stable throughout the duration of treatment. 4.

Implantation of fibrin gel combined with plasmids carrying BMP2/BMP7 genes into femoral bone defects showed a trend toward increased bone volume in the pBMP2/7 group compared to fibrin gel alone [ 46 ].

MBOAT7 (rs641738), evaluated under a recessive model, was linked to higher CAP values and showed a trend toward greater fibrosis, suggesting a role in lipid remodeling and steatosis-driven fibrosis progression.

In terms of arousal, the control group showed a trend of increasing arousal scores from pre- to post-test, whereas the experimental group showed a decreasing trend.