Barely Significant
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“showed a trend”

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In the literature

In MR, LPL showed a trend towards an inverse causal relationship with CHD, in line with previous studies indicating a higher risk of CHD in subjects with loss-of-function variants of LPL, as well as a protective relationship between triglyceride-lowering LPL variants and CHD in MR analyses. 23 PON3 inhibits LDL-oxidation and has been shown to slow atherosclerosis progression. 24 In this study, PON3 was strongly negatively associated with both family history of CHD and SIS; however, it did not meet the corrected significance level in our MR analysis.
61 Paired analysis of EVs from the AH of 19 patients with UM before and after brachytherapy showed a trend toward increased EV concentration, as well as increased CD63/81 + and CD9/CD63/81 + EV subpopulations and a decreased CD63 + EV subpopulation. 61 Thus, the authors hypothesized that CD63/81 + and CD9/CD63/81 + EVs may be tumor derived and represent UM biomarkers.
Results Exposure to DEHP was associated with early tumorigenesis and low tumor infiltration of lymphocytes of human breast tumors First, we observed that tumor infiltration of CD3 + , cytotoxic CD8 + , and cytotoxic granzyme B + (GZMB + ) lymphocytes showed a trend in positive correlation with diagnosis age ( Figure S1 A), suggesting the involvement of immune dysfunction in certain populations of EOBC patients.